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Entry version 21 (07 Oct 2020)
Sequence version 1 (16 May 2012)
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Protein

LPD22 domain-containing protein

Gene

PHAMO_180135

Organism
Phaeospirillum molischianum DSM 120
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
LPD22 domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PHAMO_180135Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhaeospirillum molischianum DSM 120Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1150626 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaePhaeospirillum
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000004169 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2096 – 2115HelicalSequence analysisAdd BLAST20
Transmembranei2127 – 2146HelicalSequence analysisAdd BLAST20
Transmembranei2174 – 2195HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
1150626.PHAMO_180135

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 130LPD22InterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 25DisorderedSequence analysisAdd BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1421 – 1448Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502ZABJ, Bacteria

Database of Orthologous Groups

More...
OrthoDBi
142817at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040738, LPD22

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18834, LPD22, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H8FP78-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDFASFMDG SPDAKTEDPN SFGSFMASVE SDRSARLGSN LIAAADTNPD
60 70 80 90 100
AHAKAMEIGR QIGAPADAIA ANLGEGERMA KLQKMREALG SAPKLAEFLT
110 120 130 140 150
SDPDMAKLSS DDFSALTRLE GSMTAAASFG RGVDLLQSML YGAAEWSGEA
160 170 180 190 200
TGSKDLATWA RRGRQANEAE AAAHGTRSQF LNIGGVGDAA QWGKETLFEQ
210 220 230 240 250
LPLMSPALAG SLAGAGIGGA VGGPPGAVAG GLIGGFAPSV VMGIGETQGQ
260 270 280 290 300
LKQKDPNAEA PVSVAVGGIA IGLLDSIVPG LIGRRLVTVL GKEAAEKVTH
310 320 330 340 350
EGIAAAAGAL LKGAGIEGAT EAAQEAIGEF AAAHGADQAV DWQGLGPQMV
360 370 380 390 400
EAAAAGFLMG GAFEGGAKGI EKLAERQKVA EAKKTAAALT DAVAATQESK
410 420 430 440 450
LATRDPERFA DLVRQIAGDG QLHIPAESLQ SLYQSGVIDD ATLDGLDVTA
460 470 480 490 500
QLPEALAAGG DVLVDPAKYL SAASKLTPEA LAQMIGSTRR GATDMTMKEV
510 520 530 540 550
EAFLADPARR KDATDLIESL SIQYEGAKPG QIVEDEVTQA LMKTGHYTES
560 570 580 590 600
QAKAQAVLWR ERMIQRGADR GMDPDALWLE EKPRILGPAP RLPVDDIDLV
610 620 630 640 650
LERIRSGNEV KPPRQPVLDI FRHLGGVKPG SMLAQELAAM GITPKEAPGL
660 670 680 690 700
FRPTGIGSAD QVVVSEHEVL RDNQVKADNS GNGYADHDAL MQAVAREWAG
710 720 730 740 750
DPLQTQAYRD RAARLDAPVR DLRKALEAEG IIPELATKEN VLRLMERDQS
760 770 780 790 800
ADALGQEAGR VISALQEIVA GADEATVSDL RPDLVSLGGA SDVSFVWGNS
810 820 830 840 850
KRGLEHIGRK RGASVVLQVI RAVALGKITK QVEGKKTVHL ELDGTEAVLS
860 870 880 890 900
LDLNGDRKTW LLTGWEIGKP DARGEVGAQS KATQNAPTFS RDDLGAGLQA
910 920 930 940 950
IISRGDPLFQ PNGGGLRGSF DPIDDTIRLF ETANLSTFLH EGGHLWLFQM
960 970 980 990 1000
VRDLGDERLR PEARDRTVRD LQTVMDWMNV EIDVATASPG DIQAAIPVEA
1010 1020 1030 1040 1050
HEKWARGIEA YLMEGKAPSV ALRDVFQRFS AWLIRTYKKV RNLSVKLTPE
1060 1070 1080 1090 1100
IRGVMDRLLA SDEAIEQARR DSVFRVPSEL LAVLALAERR EIEQAQEQAA
1110 1120 1130 1140 1150
LEAKAELQGR AMRELARERL AWWKTEREGV RAEVEADVRT RPAYRVVALS
1160 1170 1180 1190 1200
KGIGPDGAKL IDPDTGEAQV LKLDRKALVA EYGEEIVRLL PTGVTVAKGG
1210 1220 1230 1240 1250
VNHHIVAGWF GLPHGDALRL ALMDAKANPQ AEVIERETDA RMRERHGDMV
1260 1270 1280 1290 1300
TDGRIAEDAA DIVATGKAIE AVALQAKCLK RLVGDTIDKA AARRQAEQGA
1310 1320 1330 1340 1350
GSRSDDQARI DAAATSTDQV INAGVPAEGT TAAQVAEAMA AGEAKAAPLQ
1360 1370 1380 1390 1400
RTAQRAAVRQ VRNILAGMDH TAIREAAAKF IAARQVSQAT DATMYRAQAK
1410 1420 1430 1440 1450
RHEKRATLAL AARDYVEAHD AKQQQLLNME LERLAREART EVEKFQAKAR
1460 1470 1480 1490 1500
RLNKPDGKLA ATMDEDFFRA ARQVLARYGL ARANSDFDTK VWLDRLEETD
1510 1520 1530 1540 1550
PAGAEDIAAI IANLTKAPTP GQVKSRIMPD GRRVEIAPDY RDMTMAAFRD
1560 1570 1580 1590 1600
LRDGVQALLT MGRNARSALV DGERVEFERI TEEARAQLEP FQRDRDLSHM
1610 1620 1630 1640 1650
PTDTEKNRHG LLGIVASWRI AESWARLADL GKVGVMTKYV IRPVFDAVHA
1660 1670 1680 1690 1700
YRTARREIQE KLLAILSPVR DDLAKPQLIQ APELKDGFYF SNKGQLIHAI
1710 1720 1730 1740 1750
LHTGNESNMK KLLVGWKWAT LNKDGSFDRS GWASFMSRMF ADGVVTKADM
1760 1770 1780 1790 1800
DMVQSVWDLL ESTKPAAQAA HKAMYGVGFK EIEASPIKTP FGEYRGGYVP
1810 1820 1830 1840 1850
ALTEKSLNVD GAGQEAVEAL TAQQSGAMFP AAARGFTENR VENYAEPLTL
1860 1870 1880 1890 1900
DLLLLPAHLN KVLLFSHVGP AVRQTARLLK RRDFREVVGR YDPSAIDGVL
1910 1920 1930 1940 1950
WPMLERAVRQ TVETPALTPG GRKAAEFARY FRTTAGLQAM CGNLLNAAQQ
1960 1970 1980 1990 2000
ITGISSAATM VGGGALARSL VTVWRNPESS TAAIMAKSAL MRERMDSSAY
2010 2020 2030 2040 2050
EASMEIEKIL KDHTLLGKGQ SFAQRHGYFA QQLAQNFVDR VVWWAAYDKE
2060 2070 2080 2090 2100
IGNGTAEAEA VQQADSAVRL TQGSFSPESV AAVEAGNAWV RLFTQFMTYF
2110 2120 2130 2140 2150
MAQGNMIATE VMIALRTMTG GNLSRRLAGV YVFAFLIPAV VAEAIMQAGR
2160 2170 2180 2190 2200
GELGDEDDDG WLDDLASLFL LPQLRFFAAM IPVAGPVAML GINALNDKPY
2210 2220 2230 2240 2250
DDRLAASPAV TLMESAGRAA VTTAKAVAGD GDKSRAVSDA MNAVSVATGI
2260 2270 2280 2290
PTGMIRKPAS YAVDVAEGDS RPRHLGNVVS GILTGQDGTA R
Length:2,291
Mass (Da):246,070
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB987AA87026A235D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CAHP01000010 Genomic DNA Translation: CCG40166.1

NCBI Reference Sequences

More...
RefSeqi
WP_002726193.1, NZ_CAHP01000010.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CCG40166; CCG40166; PHAMO_180135

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAHP01000010 Genomic DNA Translation: CCG40166.1
RefSeqiWP_002726193.1, NZ_CAHP01000010.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi1150626.PHAMO_180135

Genome annotation databases

EnsemblBacteriaiCCG40166; CCG40166; PHAMO_180135

Phylogenomic databases

eggNOGiENOG502ZABJ, Bacteria
OrthoDBi142817at2

Family and domain databases

InterProiView protein in InterPro
IPR040738, LPD22
PfamiView protein in Pfam
PF18834, LPD22, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH8FP78_PHAMO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H8FP78
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 7, 2020
This is version 21 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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