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UniProtKB - H8FP78 (H8FP78_PHAMO)

Entry version 21 (07 Oct 2020)
Sequence version 1 (16 May 2012)
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Protein

LPD22 domain-containing protein

Gene

PHAMO_180135

Organism
Phaeospirillum molischianum DSM 120
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
LPD22 domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PHAMO_180135Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhaeospirillum molischianum DSM 120Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1150626 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Phaeospirillum ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000004169 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2096 – 2115HelicalSequence analysisAdd BLAST20
Transmembranei2127 – 2146HelicalSequence analysisAdd BLAST20
Transmembranei2174 – 2195HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		1150626.PHAMO_180135

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 130LPD22InterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 25DisorderedSequence analysisAdd BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1421 – 1448Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502ZABJ, Bacteria

Database of Orthologous Groups

More...OrthoDBi		142817at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR040738, LPD22

Pfam protein domain database

More...Pfami		View protein in Pfam
PF18834, LPD22, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H8FP78-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDFASFMDG SPDAKTEDPN SFGSFMASVE SDRSARLGSN LIAAADTNPD 
        60         70         80         90        100
AHAKAMEIGR QIGAPADAIA ANLGEGERMA KLQKMREALG SAPKLAEFLT 
       110        120        130        140        150
SDPDMAKLSS DDFSALTRLE GSMTAAASFG RGVDLLQSML YGAAEWSGEA 
       160        170        180        190        200
TGSKDLATWA RRGRQANEAE AAAHGTRSQF LNIGGVGDAA QWGKETLFEQ 
       210        220        230        240        250
LPLMSPALAG SLAGAGIGGA VGGPPGAVAG GLIGGFAPSV VMGIGETQGQ 
       260        270        280        290        300
LKQKDPNAEA PVSVAVGGIA IGLLDSIVPG LIGRRLVTVL GKEAAEKVTH 
       310        320        330        340        350
EGIAAAAGAL LKGAGIEGAT EAAQEAIGEF AAAHGADQAV DWQGLGPQMV 
       360        370        380        390        400
EAAAAGFLMG GAFEGGAKGI EKLAERQKVA EAKKTAAALT DAVAATQESK 
       410        420        430        440        450
LATRDPERFA DLVRQIAGDG QLHIPAESLQ SLYQSGVIDD ATLDGLDVTA 
       460        470        480        490        500
QLPEALAAGG DVLVDPAKYL SAASKLTPEA LAQMIGSTRR GATDMTMKEV 
       510        520        530        540        550
EAFLADPARR KDATDLIESL SIQYEGAKPG QIVEDEVTQA LMKTGHYTES 
       560        570        580        590        600
QAKAQAVLWR ERMIQRGADR GMDPDALWLE EKPRILGPAP RLPVDDIDLV 
       610        620        630        640        650
LERIRSGNEV KPPRQPVLDI FRHLGGVKPG SMLAQELAAM GITPKEAPGL 
       660        670        680        690        700
FRPTGIGSAD QVVVSEHEVL RDNQVKADNS GNGYADHDAL MQAVAREWAG 
       710        720        730        740        750
DPLQTQAYRD RAARLDAPVR DLRKALEAEG IIPELATKEN VLRLMERDQS 
       760        770        780        790        800
ADALGQEAGR VISALQEIVA GADEATVSDL RPDLVSLGGA SDVSFVWGNS 
       810        820        830        840        850
KRGLEHIGRK RGASVVLQVI RAVALGKITK QVEGKKTVHL ELDGTEAVLS 
       860        870        880        890        900
LDLNGDRKTW LLTGWEIGKP DARGEVGAQS KATQNAPTFS RDDLGAGLQA 
       910        920        930        940        950
IISRGDPLFQ PNGGGLRGSF DPIDDTIRLF ETANLSTFLH EGGHLWLFQM 
       960        970        980        990       1000
VRDLGDERLR PEARDRTVRD LQTVMDWMNV EIDVATASPG DIQAAIPVEA 
      1010       1020       1030       1040       1050
HEKWARGIEA YLMEGKAPSV ALRDVFQRFS AWLIRTYKKV RNLSVKLTPE 
      1060       1070       1080       1090       1100
IRGVMDRLLA SDEAIEQARR DSVFRVPSEL LAVLALAERR EIEQAQEQAA 
      1110       1120       1130       1140       1150
LEAKAELQGR AMRELARERL AWWKTEREGV RAEVEADVRT RPAYRVVALS 
      1160       1170       1180       1190       1200
KGIGPDGAKL IDPDTGEAQV LKLDRKALVA EYGEEIVRLL PTGVTVAKGG 
      1210       1220       1230       1240       1250
VNHHIVAGWF GLPHGDALRL ALMDAKANPQ AEVIERETDA RMRERHGDMV 
      1260       1270       1280       1290       1300
TDGRIAEDAA DIVATGKAIE AVALQAKCLK RLVGDTIDKA AARRQAEQGA 
      1310       1320       1330       1340       1350
GSRSDDQARI DAAATSTDQV INAGVPAEGT TAAQVAEAMA AGEAKAAPLQ 
      1360       1370       1380       1390       1400
RTAQRAAVRQ VRNILAGMDH TAIREAAAKF IAARQVSQAT DATMYRAQAK 
      1410       1420       1430       1440       1450
RHEKRATLAL AARDYVEAHD AKQQQLLNME LERLAREART EVEKFQAKAR 
      1460       1470       1480       1490       1500
RLNKPDGKLA ATMDEDFFRA ARQVLARYGL ARANSDFDTK VWLDRLEETD 
      1510       1520       1530       1540       1550
PAGAEDIAAI IANLTKAPTP GQVKSRIMPD GRRVEIAPDY RDMTMAAFRD 
      1560       1570       1580       1590       1600
LRDGVQALLT MGRNARSALV DGERVEFERI TEEARAQLEP FQRDRDLSHM 
      1610       1620       1630       1640       1650
PTDTEKNRHG LLGIVASWRI AESWARLADL GKVGVMTKYV IRPVFDAVHA 
      1660       1670       1680       1690       1700
YRTARREIQE KLLAILSPVR DDLAKPQLIQ APELKDGFYF SNKGQLIHAI 
      1710       1720       1730       1740       1750
LHTGNESNMK KLLVGWKWAT LNKDGSFDRS GWASFMSRMF ADGVVTKADM 
      1760       1770       1780       1790       1800
DMVQSVWDLL ESTKPAAQAA HKAMYGVGFK EIEASPIKTP FGEYRGGYVP 
      1810       1820       1830       1840       1850
ALTEKSLNVD GAGQEAVEAL TAQQSGAMFP AAARGFTENR VENYAEPLTL 
      1860       1870       1880       1890       1900
DLLLLPAHLN KVLLFSHVGP AVRQTARLLK RRDFREVVGR YDPSAIDGVL 
      1910       1920       1930       1940       1950
WPMLERAVRQ TVETPALTPG GRKAAEFARY FRTTAGLQAM CGNLLNAAQQ 
      1960       1970       1980       1990       2000
ITGISSAATM VGGGALARSL VTVWRNPESS TAAIMAKSAL MRERMDSSAY 
      2010       2020       2030       2040       2050
EASMEIEKIL KDHTLLGKGQ SFAQRHGYFA QQLAQNFVDR VVWWAAYDKE 
      2060       2070       2080       2090       2100
IGNGTAEAEA VQQADSAVRL TQGSFSPESV AAVEAGNAWV RLFTQFMTYF 
      2110       2120       2130       2140       2150
MAQGNMIATE VMIALRTMTG GNLSRRLAGV YVFAFLIPAV VAEAIMQAGR 
      2160       2170       2180       2190       2200
GELGDEDDDG WLDDLASLFL LPQLRFFAAM IPVAGPVAML GINALNDKPY 
      2210       2220       2230       2240       2250
DDRLAASPAV TLMESAGRAA VTTAKAVAGD GDKSRAVSDA MNAVSVATGI 
      2260       2270       2280       2290 
PTGMIRKPAS YAVDVAEGDS RPRHLGNVVS GILTGQDGTA R
Length:2,291
Mass (Da):246,070
Last modified:May 16, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB987AA87026A235D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CAHP01000010 Genomic DNA Translation: CCG40166.1

NCBI Reference Sequences

More...RefSeqi		WP_002726193.1, NZ_CAHP01000010.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		CCG40166; CCG40166; PHAMO_180135

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAHP01000010 Genomic DNA Translation: CCG40166.1
RefSeqiWP_002726193.1, NZ_CAHP01000010.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi1150626.PHAMO_180135

Genome annotation databases

EnsemblBacteriaiCCG40166; CCG40166; PHAMO_180135

Phylogenomic databases

eggNOGiENOG502ZABJ, Bacteria
OrthoDBi142817at2

Family and domain databases

InterProiView protein in InterPro
IPR040738, LPD22
PfamiView protein in Pfam
PF18834, LPD22, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH8FP78_PHAMO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H8FP78
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2012
Last sequence update: May 16, 2012
Last modified: October 7, 2020
This is version 21 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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