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Protein
Submitted name:

Guanine nucleotide-binding protein subunit beta-4

Gene

GNB4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein subunit beta-4Imported
Gene namesi
Name:GNB4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000114450.9
HGNCiHGNC:20731 GNB4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000114450

PTM / Processingi

Proteomic databases

EPDiH7C5J5
MaxQBiH7C5J5
PeptideAtlasiH7C5J5
PRIDEiH7C5J5

Expressioni

Gene expression databases

BgeeiENSG00000114450 Expressed in 207 organ(s), highest expression level in upper arm skin
ExpressionAtlasiH7C5J5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C5J5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 165WD_REPEATS_REGIONInterPro annotationAdd BLAST165
Repeati62 – 102WDPROSITE-ProRule annotationAdd BLAST41
Repeati103 – 144WDPROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0286 Eukaryota
ENOG410XQUX LUCA
GeneTreeiENSGT00760000119239

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19850 PTHR19850, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 3 hits
PRINTSiPR00319 GPROTEINB
SMARTiView protein in SMART
SM00320 WD40, 3 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

H7C5J5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XLIIWDSYTT NKMHAIPLRS SWVMTCAYAP SGNYVACGGL DNICSIYNLK
60 70 80 90 100
TREGNVRVSR ELPGHTGYLS CCRFLDDSQI VTSSGDTTCA LWDIETAQQT
110 120 130 140 150
TTFTGHSGDV MSLSLSPDMR TFVSGACDAS SKLWDIRDGM CRQSFTGHVS
160
DINAVSVSLL VMTTV
Length:165
Mass (Da):17,979
Last modified:April 18, 2012 - v1
Checksum:iF422CDC93BF0AA46
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9HAV0GBB4_HUMAN
Guanine nucleotide-binding protein ...
GNB4
340Annotation score:
C9JD14C9JD14_HUMAN
Guanine nucleotide-binding protein ...
GNB4
79Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007620 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000466899; ENSP00000420066; ENSG00000114450
UCSCiuc062qex.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007620 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C5J5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH7C5J5
MaxQBiH7C5J5
PeptideAtlasiH7C5J5
PRIDEiH7C5J5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000466899; ENSP00000420066; ENSG00000114450
UCSCiuc062qex.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000114450.9
HGNCiHGNC:20731 GNB4
OpenTargetsiENSG00000114450
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0286 Eukaryota
ENOG410XQUX LUCA
GeneTreeiENSGT00760000119239

Miscellaneous databases

ChiTaRSiGNB4 human

Gene expression databases

BgeeiENSG00000114450 Expressed in 207 organ(s), highest expression level in upper arm skin
ExpressionAtlasiH7C5J5 baseline and differential

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19850 PTHR19850, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 3 hits
PRINTSiPR00319 GPROTEINB
SMARTiView protein in SMART
SM00320 WD40, 3 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C5J5_HUMAN
AccessioniPrimary (citable) accession number: H7C5J5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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