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Protein
Submitted name:

CLIP-associating protein 2

Gene

CLASP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
CLIP-associating protein 2Imported
Gene namesi
Name:CLASP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000163539.16
HGNCiHGNC:17078 CLASP2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163539

PTM / Processingi

Proteomic databases

EPDiH7C4X8
MaxQBiH7C4X8
PeptideAtlasiH7C4X8
PRIDEiH7C4X8

Expressioni

Gene expression databases

BgeeiENSG00000163539 Expressed in 228 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH7C4X8 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH7C4X8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili82 – 106Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2956 Eukaryota
ENOG410ZMY0 LUCA
GeneTreeiENSGT00390000001762

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR028399 CLASP_1
PANTHERiPTHR21567:SF28 PTHR21567:SF28, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

H7C4X8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGMSDPRAGG DATDSSQTAL DNKASLLHSM PTHSSPRSRD YNPYNYSDSI
60 70 80 90 100
SPFNKSALKE AMFDDDADQF PDDLSLDHSD LVAELLKELS NHNERVEERK
110 120 130 140 150
IALYELMKLT QEESFSVWDE HFKTILLLLL ETLGDKEPTI RALALKVLRE
160 170 180
ILRHQPARFK NYAELTVMKT LEAHKDPHKE VDTQ
Length:184
Mass (Da):20,995
Last modified:April 18, 2012 - v1
Checksum:i4EDC0775F67CB6E5
GO

Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O75122CLAP2_HUMAN
CLIP-associating protein 2
CLASP2 KIAA0627
1,294Annotation score:
E7EW49E7EW49_HUMAN
CLIP-associating protein 2
CLASP2
1,514Annotation score:
E7ERI8E7ERI8_HUMAN
CLIP-associating protein 2
CLASP2
1,513Annotation score:
E3W994E3W994_HUMAN
CLIP-associating protein 2
CLASP2
1,273Annotation score:
J3KR49J3KR49_HUMAN
CLIP-associating protein 2
CLASP2
1,293Annotation score:
A0A0U1RQI6A0A0U1RQI6_HUMAN
CLIP-associating protein 2
CLASP2
1,304Annotation score:
H7C4I5H7C4I5_HUMAN
CLIP-associating protein 2
CLASP2
205Annotation score:
H7C5M8H7C5M8_HUMAN
CLIP-associating protein 2
CLASP2
220Annotation score:
B3KR06B3KR06_HUMAN
Cytoplasmic linker associated prote...
CLASP2 hCG_1997378
454Annotation score:
D6RBU8D6RBU8_HUMAN
CLIP-associating protein 2
CLASP2
233Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093114 Genomic DNA No translation available.
AC113170 Genomic DNA No translation available.
AC132515 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000476251; ENSP00000418488; ENSG00000163539
UCSCiuc062hyc.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093114 Genomic DNA No translation available.
AC113170 Genomic DNA No translation available.
AC132515 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C4X8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH7C4X8
MaxQBiH7C4X8
PeptideAtlasiH7C4X8
PRIDEiH7C4X8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000476251; ENSP00000418488; ENSG00000163539
UCSCiuc062hyc.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000163539.16
HGNCiHGNC:17078 CLASP2
OpenTargetsiENSG00000163539
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2956 Eukaryota
ENOG410ZMY0 LUCA
GeneTreeiENSGT00390000001762

Miscellaneous databases

ChiTaRSiCLASP2 human

Gene expression databases

BgeeiENSG00000163539 Expressed in 228 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH7C4X8 baseline and differential

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR028399 CLASP_1
PANTHERiPTHR21567:SF28 PTHR21567:SF28, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C4X8_HUMAN
AccessioniPrimary (citable) accession number: H7C4X8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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