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Protein
Submitted name:

Roundabout homolog 2

Gene

ROBO2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Roundabout homolog 2Imported
Gene namesi
Name:ROBO2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000185008.17
HGNCiHGNC:10250 ROBO2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185008

PTM / Processingi

Proteomic databases

PeptideAtlasiH7C4U9

Expressioni

Gene expression databases

BgeeiENSG00000185008 Expressed in 148 organ(s), highest expression level in forebrain
ExpressionAtlasiH7C4U9 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4222 Eukaryota
ENOG410XPQS LUCA
GeneTreeiENSGT00930000150875

Family and domain databases

InterProiView protein in InterPro
IPR032985 Robo2
PANTHERiPTHR44096:SF2 PTHR44096:SF2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

H7C4U9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XSWPATSLPV NNSNSGPNEI GNFGRGDVLP PVPGQGDKTA TMLSDGAIYS
60 70 80 90 100
SIDFTTKTSY NSSSQITQAT PYATTQILHS NSIHELAVDL PDPQWKSSIQ
110 120 130 140 150
QKTDLMGFGY SLPDQNKGNN ALLYIPDYRL AEGLSNRMPH NQSQDFSTTS
160 170 180 190 200
SHNSSERSGS LSGGKGGKKK KNKNSSKPQK NNGSTWANVP LPPPPVQPLP
210
GTELEHYAVE QQEN
Length:214
Mass (Da):23,066
Last modified:October 5, 2016 - v8
Checksum:iD661A38B390EE296
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9HCK4ROBO2_HUMAN
Roundabout homolog 2
ROBO2 KIAA1568
1,378Annotation score:
F8W703F8W703_HUMAN
Roundabout homolog 2
ROBO2
1,439Annotation score:
F8WBR3F8WBR3_HUMAN
Roundabout homolog 2
ROBO2
564Annotation score:
R4GMM8R4GMM8_HUMAN
Roundabout homolog 2
ROBO2
1,070Annotation score:
A0A087WWM5A0A087WWM5_HUMAN
Roundabout homolog 2
ROBO2
1,250Annotation score:
H7C4V8H7C4V8_HUMAN
Roundabout homolog 2
ROBO2
342Annotation score:
H7C4J7H7C4J7_HUMAN
Roundabout homolog 2
ROBO2
198Annotation score:
H7C4W9H7C4W9_HUMAN
Roundabout homolog 2
ROBO2
208Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei214Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016942 Genomic DNA No translation available.
AC024256 Genomic DNA No translation available.
AC026877 Genomic DNA No translation available.
AC067717 Genomic DNA No translation available.
AC117514 Genomic DNA No translation available.
AC126467 Genomic DNA No translation available.
AC130004 Genomic DNA No translation available.
AC131154 Genomic DNA No translation available.
KC876890 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000471893; ENSP00000418190; ENSG00000185008
UCSCiuc062lpt.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016942 Genomic DNA No translation available.
AC024256 Genomic DNA No translation available.
AC026877 Genomic DNA No translation available.
AC067717 Genomic DNA No translation available.
AC117514 Genomic DNA No translation available.
AC126467 Genomic DNA No translation available.
AC130004 Genomic DNA No translation available.
AC131154 Genomic DNA No translation available.
KC876890 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH7C4U9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000471893; ENSP00000418190; ENSG00000185008
UCSCiuc062lpt.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000185008.17
HGNCiHGNC:10250 ROBO2
OpenTargetsiENSG00000185008
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4222 Eukaryota
ENOG410XPQS LUCA
GeneTreeiENSGT00930000150875

Miscellaneous databases

ChiTaRSiROBO2 human

Gene expression databases

BgeeiENSG00000185008 Expressed in 148 organ(s), highest expression level in forebrain
ExpressionAtlasiH7C4U9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR032985 Robo2
PANTHERiPTHR44096:SF2 PTHR44096:SF2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C4U9_HUMAN
AccessioniPrimary (citable) accession number: H7C4U9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: October 5, 2016
Last modified: November 7, 2018
This is version 44 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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