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Protein
Submitted name:

AF4/FMR2 family member 3

Gene

AFF3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
AF4/FMR2 family member 3Imported
Gene namesi
Name:AFF3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000144218.18
HGNCiHGNC:6473 AFF3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000144218

PTM / Processingi

Proteomic databases

PeptideAtlasiH7C4C2
PRIDEiH7C4C2

Expressioni

Gene expression databases

BgeeiENSG00000144218 Expressed in 192 organ(s), highest expression level in neocortex
ExpressionAtlasiH7C4C2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C4C2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063217

Family and domain databases

InterProiView protein in InterPro
IPR007797 TF_AF4/FMR2
PANTHERiPTHR10528 PTHR10528, 1 hit
PfamiView protein in Pfam
PF05110 AF-4, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

H7C4C2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GHRDCKRQKL VFDDMPRSAD YFMQEAKRMK HKADAMVEKF GKALNYAEAA
60 70 80 90 100
LSFIECGNAM EQGPMESKSP YTMYSETVEL IRYAMRLKTH SGPNATPEDK
110 120 130 140 150
QLAALCYRCL ALLYWRMFRL KRDHAVKYSK ALIDYFKNSS KAAQAPSPWG
160 170 180
ASGNSVGSQG SLSNASALSP STIVSIPQRI HQMAA
Length:185
Mass (Da):20,697
Last modified:April 18, 2012 - v1
Checksum:i532E436CD5D5364B
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P51826AFF3_HUMAN
AF4/FMR2 family member 3
AFF3 LAF4
1,226Annotation score:
H7C3W3H7C3W3_HUMAN
AF4/FMR2 family member 3
AFF3
179Annotation score:
C9JUC4C9JUC4_HUMAN
AF4/FMR2 family member 3
AFF3
155Annotation score:
C9J847C9J847_HUMAN
AF4/FMR2 family member 3
AFF3
114Annotation score:
C9JMS1C9JMS1_HUMAN
AF4/FMR2 family member 3
AFF3
99Annotation score:
C9JZ66C9JZ66_HUMAN
AF4/FMR2 family member 3
AFF3
128Annotation score:
C9JC67C9JC67_HUMAN
AF4/FMR2 family member 3
AFF3
155Annotation score:
C9J622C9J622_HUMAN
AF4/FMR2 family member 3
AFF3
161Annotation score:
C9JUY1C9JUY1_HUMAN
AF4/FMR2 family member 3
AFF3
183Annotation score:
C9JIB1C9JIB1_HUMAN
AF4/FMR2 family member 3
AFF3
17Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei185Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010736 Genomic DNA No translation available.
AC018690 Genomic DNA No translation available.
AC073118 Genomic DNA No translation available.
AC092667 Genomic DNA No translation available.
AC093373 Genomic DNA No translation available.
AC114793 Genomic DNA No translation available.
AC133108 Genomic DNA No translation available.
KF456685 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000445815; ENSP00000416685; ENSG00000144218
UCSCiuc061mhn.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010736 Genomic DNA No translation available.
AC018690 Genomic DNA No translation available.
AC073118 Genomic DNA No translation available.
AC092667 Genomic DNA No translation available.
AC093373 Genomic DNA No translation available.
AC114793 Genomic DNA No translation available.
AC133108 Genomic DNA No translation available.
KF456685 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C4C2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH7C4C2
PRIDEiH7C4C2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000445815; ENSP00000416685; ENSG00000144218
UCSCiuc061mhn.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000144218.18
HGNCiHGNC:6473 AFF3
OpenTargetsiENSG00000144218
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000063217

Miscellaneous databases

ChiTaRSiAFF3 human

Gene expression databases

BgeeiENSG00000144218 Expressed in 192 organ(s), highest expression level in neocortex
ExpressionAtlasiH7C4C2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007797 TF_AF4/FMR2
PANTHERiPTHR10528 PTHR10528, 1 hit
PfamiView protein in Pfam
PF05110 AF-4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C4C2_HUMAN
AccessioniPrimary (citable) accession number: H7C4C2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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