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Protein
Submitted name:

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

Gene

ACAP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2Imported
Gene namesi
Name:ACAP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000114331.13
HGNCiHGNC:16469 ACAP2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000114331

PTM / Processingi

Proteomic databases

PeptideAtlasiH7C3K3
PRIDEiH7C3K3

Expressioni

Gene expression databases

BgeeiENSG00000114331 Expressed in 238 organ(s), highest expression level in blood
ExpressionAtlasiH7C3K3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C3K3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 79Arf-GAPInterPro annotationAdd BLAST79

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118874

Family and domain databases

Gene3Di3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
PfamiView protein in Pfam
PF01412 ArfGap, 1 hit
SMARTiView protein in SMART
SM00105 ArfGap, 1 hit
SUPFAMiSSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115 ARFGAP, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H7C3K3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XSLGVHFSKV RSLTLDTWEP ELLKLMCELG NDVINRVYEA NVEKMGIKKP
60 70 80 90 100
QPGQRQEKEA YIRAKYVERK FVDKYSISLS PPEQQKKFVS KSSEEKRLSI
110 120 130 140 150
SKFGPGDQVR ASAQSSVIAV NSDEARRESL FCPDELDSLF SYFDTSSKLR
160 170 180 190 200
SIRSNDSGIQ QSSDDGRESL PSTVSANSLY EPEGERQDSS MFLDSKHLNP
210 220
GLQLYRASYE KNLPKMAEAL AHGADVNW
Length:228
Mass (Da):25,719
Last modified:October 5, 2016 - v8
Checksum:i7E4D9E0E13AADA58
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q15057ACAP2_HUMAN
Arf-GAP with coiled-coil, ANK repea...
ACAP2 CENTB2, KIAA0041
778Annotation score:
A0A087X1H5A0A087X1H5_HUMAN
Arf-GAP with coiled-coil, ANK repea...
ACAP2
777Annotation score:
A0A0U1RQT1A0A0U1RQT1_HUMAN
Arf-GAP with coiled-coil, ANK repea...
ACAP2
547Annotation score:
H7C3Q8H7C3Q8_HUMAN
Arf-GAP with coiled-coil, ANK repea...
ACAP2
256Annotation score:
C9J8L1C9J8L1_HUMAN
Arf-GAP with coiled-coil, ANK repea...
ACAP2
51Annotation score:
F8WAU0F8WAU0_HUMAN
Arf-GAP with coiled-coil, ANK repea...
ACAP2
49Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei228Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090018 Genomic DNA No translation available.
AC091633 Genomic DNA No translation available.
AC126170 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000450200; ENSP00000412338; ENSG00000114331
UCSCiuc062rqu.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090018 Genomic DNA No translation available.
AC091633 Genomic DNA No translation available.
AC126170 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C3K3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH7C3K3
PRIDEiH7C3K3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000450200; ENSP00000412338; ENSG00000114331
UCSCiuc062rqu.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000114331.13
HGNCiHGNC:16469 ACAP2
OpenTargetsiENSG00000114331
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118874

Miscellaneous databases

ChiTaRSiACAP2 human

Gene expression databases

BgeeiENSG00000114331 Expressed in 238 organ(s), highest expression level in blood
ExpressionAtlasiH7C3K3 baseline and differential

Family and domain databases

Gene3Di3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
PfamiView protein in Pfam
PF01412 ArfGap, 1 hit
SMARTiView protein in SMART
SM00105 ArfGap, 1 hit
SUPFAMiSSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115 ARFGAP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C3K3_HUMAN
AccessioniPrimary (citable) accession number: H7C3K3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 52 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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