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Protein
Submitted name:

All-trans-retinol 13,14-reductase

Gene

RETSAT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
All-trans-retinol 13,14-reductaseImported
Gene namesi
Name:RETSATImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000042445.13
HGNCiHGNC:25991 RETSAT

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000042445

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500360871122 – 399Sequence analysisAdd BLAST378

Proteomic databases

MaxQBiH7C3J0
PeptideAtlasiH7C3J0
PRIDEiH7C3J0

Expressioni

Gene expression databases

BgeeiENSG00000042445 Expressed in 222 organ(s), highest expression level in adipose tissue
ExpressionAtlasiH7C3J0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C3J0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili378 – 398Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4254 Eukaryota
COG1233 LUCA
GeneTreeiENSGT00390000017613

Family and domain databases

Gene3Di3.50.50.60, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
SUPFAMiSSF51905 SSF51905, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H7C3J0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XPLVLLLAVL LLAVLCKVYL GLFSGSSPNP FSEDVKRPPA PLVTDKEARK
60 70 80 90 100
KVLKQGVTPN HSAFSMHALL VNHYMKGGFY PRGGSSEIAF HTIPVIQRAG
110 120 130 140 150
GAVLTKATVQ SVLLDSAGKA CGVSVKKGHE LVNIYCPIVV SNAGLFNTYE
160 170 180 190 200
HLLPGNARCL PGVKQQLGTV RPGLGMTSVF ICLRGTKEDL HLPSTNYYVY
210 220 230 240 250
YDTDMDQAME RYVSMPREEA AEHIPLLFFA FPSAKDPTWE DRFPGRSTMI
260 270 280 290 300
MLIPTAYEWF EEWQAELKGK RGSDYETFKN SFVEASMSVV LKLFPQLEGK
310 320 330 340 350
VESVTAGSPL TNQFYLAAPR GACYGADHDL GRLHPCVMAS LRAQSPIPNL
360 370 380 390
YLTGQDIFTC GLVGALQGAL LCSSAILKRN LYSDLKNLDS RIRAQKKKN
Length:399
Mass (Da):43,818
Last modified:April 18, 2012 - v1
Checksum:iB7CF2A8EA64B520E
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6NUM9RETST_HUMAN
All-trans-retinol 13,14-reductase
RETSAT PPSIG, UNQ439/PRO872
610Annotation score:
H7BZ16H7BZ16_HUMAN
All-trans-retinol 13,14-reductase
RETSAT
255Annotation score:
H7BZ81H7BZ81_HUMAN
All-trans-retinol 13,14-reductase
RETSAT
320Annotation score:
H0YGU3H0YGU3_HUMAN
All-trans-retinol 13,14-reductase
RETSAT
140Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC062037 Genomic DNA No translation available.
AC093162 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000449375; ENSP00000412166; ENSG00000042445
UCSCiuc061lfg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC062037 Genomic DNA No translation available.
AC093162 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C3J0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7C3J0
PeptideAtlasiH7C3J0
PRIDEiH7C3J0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000449375; ENSP00000412166; ENSG00000042445
UCSCiuc061lfg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000042445.13
HGNCiHGNC:25991 RETSAT
OpenTargetsiENSG00000042445
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4254 Eukaryota
COG1233 LUCA
GeneTreeiENSGT00390000017613

Miscellaneous databases

ChiTaRSiRETSAT human

Gene expression databases

BgeeiENSG00000042445 Expressed in 222 organ(s), highest expression level in adipose tissue
ExpressionAtlasiH7C3J0 baseline and differential

Family and domain databases

Gene3Di3.50.50.60, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
SUPFAMiSSF51905 SSF51905, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C3J0_HUMAN
AccessioniPrimary (citable) accession number: H7C3J0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: November 7, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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