UniProtKB - H7C2H4 (H7C2H4_HUMAN)
Protein
Submitted name:
Cystathionine beta-synthase
Gene
CBS
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Cystathionine beta-synthaseImported |
Gene namesi | Name:CBSImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:1550, CBS |
VEuPathDBi | HostDB:ENSG00000160200.17 |
PTM / Processingi
Proteomic databases
MaxQBi | H7C2H4 |
PeptideAtlasi | H7C2H4 |
PRIDEi | H7C2H4 |
ProteomicsDBi | 44989 |
Expressioni
Gene expression databases
Bgeei | ENSG00000160200, Expressed in right lobe of liver and 113 other tissues |
ExpressionAtlasi | H7C2H4, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 72 – 130 | CBSInterPro annotationAdd BLAST | 59 |
Keywords - Domaini
CBS domainPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00510000047027 |
Family and domain databases
Gene3Di | 3.40.50.1100, 1 hit |
InterProi | View protein in InterPro IPR000644, CBS_dom IPR036052, Trypto_synt_PLP_dependent |
Pfami | View protein in Pfam PF00571, CBS, 1 hit |
SMARTi | View protein in SMART SM00116, CBS, 1 hit |
SUPFAMi | SSF53686, SSF53686, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
H7C2H4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XGSAGSTVAV AVKAAQELQE GQRCVVILPD SVRNYMTKFL SDRWMLQKGF
60 70 80 90 100
LKEEDLTEKK PWWWHLRVQE LGLSAPLTVL PTITCGHTIE ILREKGFDQA
110 120 130 140 150
PVVDEAGVIL GMVTLGNMLS SLLAGKVQPS DQVGKVIYKQ FKQIRLTDTL
160 170 180 190 200
GRLSHILEMD HFALVVHEQI QSQDQAWAGV VGGPAGSPNQ VFLEHVHACH
210 220
HRLWLLSSTS GLRAHNRDGT APKT
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP35520 | CBS_HUMAN | Cystathionine beta-synthase | CBS | 551 | Annotation score: | ||
C9JMA6 | C9JMA6_HUMAN | Cystathionine beta-synthase | CBS | 177 | Annotation score: | ||
H7C1W6 | H7C1W6_HUMAN | Cystathionine beta-synthase | CBS | 149 | Annotation score: | ||
H7C2W0 | H7C2W0_HUMAN | Cystathionine beta-synthase | CBS | 159 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001630 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000430013; ENSP00000405929; ENSG00000160200 |
UCSCi | uc062ana.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001630 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
MaxQBi | H7C2H4 |
PeptideAtlasi | H7C2H4 |
PRIDEi | H7C2H4 |
ProteomicsDBi | 44989 |
Protocols and materials databases
Antibodypediai | 768, 460 antibodies |
Genome annotation databases
Ensembli | ENST00000430013; ENSP00000405929; ENSG00000160200 |
UCSCi | uc062ana.1, human |
Organism-specific databases
HGNCi | HGNC:1550, CBS |
OpenTargetsi | ENSG00000160200 |
VEuPathDBi | HostDB:ENSG00000160200.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00510000047027 |
Miscellaneous databases
ChiTaRSi | CBS, human |
Gene expression databases
Bgeei | ENSG00000160200, Expressed in right lobe of liver and 113 other tissues |
ExpressionAtlasi | H7C2H4, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.1100, 1 hit |
InterProi | View protein in InterPro IPR000644, CBS_dom IPR036052, Trypto_synt_PLP_dependent |
Pfami | View protein in Pfam PF00571, CBS, 1 hit |
SMARTi | View protein in SMART SM00116, CBS, 1 hit |
SUPFAMi | SSF53686, SSF53686, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H7C2H4_HUMAN | |
Accessioni | H7C2H4Primary (citable) accession number: H7C2H4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | February 10, 2021 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |