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Protein
Submitted name:

Septin-5

Gene

SEPT5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Septin-5Imported
Gene namesi
Name:SEPT5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000184702.17
HGNCiHGNC:9164 SEPT5

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184702

PTM / Processingi

Proteomic databases

MaxQBiH7C299
PeptideAtlasiH7C299

Expressioni

Gene expression databases

BgeeiENSG00000184702 Expressed in 182 organ(s), highest expression level in right frontal lobe
ExpressionAtlasiH7C299 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C299
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 106Septin-type GInterPro annotationAdd BLAST106

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00910000144020

Family and domain databases

InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
IPR030647 SEPT5
PANTHERiPTHR18884:SF68 PTHR18884:SF68, 2 hits
PfamiView protein in Pfam
PF00735 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

H7C299-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XTIVDTPGFG DAVNNTECWK PITDYVDQQF EQYFRDESGL NRKNIQDNRV
60 70 80 90 100
HCCLYFISPF GHGEIRKLKE RIREEIDKFG IHVYQFPECD SDEDEDFKQQ

DRELKV
Length:106
Mass (Da):12,649
Last modified:April 18, 2012 - v1
Checksum:i43CF32A402124207
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99719SEPT5_HUMAN
Septin-5
SEPT5 PNUTL1
369Annotation score:
G3XAH0G3XAH0_HUMAN
HCG2002594, isoform CRA_c
SEPT5 hCG_2002594
378Annotation score:
B4DJ62B4DJ62_HUMAN
HCG2002594, isoform CRA_a
hCG_2002594
322Annotation score:
E7EQM7E7EQM7_HUMAN
Septin-5
SEPT5
248Annotation score:
C9JM82C9JM82_HUMAN
Septin-5
SEPT5
301Annotation score:
E7EPG2E7EPG2_HUMAN
Septin-5
SEPT5
304Annotation score:
E7EX32E7EX32_HUMAN
Septin-5
SEPT5
337Annotation score:
F8W9E5F8W9E5_HUMAN
Septin-5
SEPT5
180Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei106Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000093 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000413258; ENSP00000404673; ENSG00000184702
UCSCiuc062bnc.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000093 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C299
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7C299
PeptideAtlasiH7C299

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413258; ENSP00000404673; ENSG00000184702
UCSCiuc062bnc.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000184702.17
HGNCiHGNC:9164 SEPT5
OpenTargetsiENSG00000184702
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00910000144020

Miscellaneous databases

ChiTaRSiSEPT5 human

Gene expression databases

BgeeiENSG00000184702 Expressed in 182 organ(s), highest expression level in right frontal lobe
ExpressionAtlasiH7C299 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
IPR030647 SEPT5
PANTHERiPTHR18884:SF68 PTHR18884:SF68, 2 hits
PfamiView protein in Pfam
PF00735 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C299_HUMAN
AccessioniPrimary (citable) accession number: H7C299
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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