ARHGAP26

Functionⁱ

GO - Molecular functionⁱ

GTPase activator activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

actin cytoskeleton organization Source: InterPro
regulation of small GTPase mediated signal transduction Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Rho GTPase-activating protein 26Imported
Gene namesⁱ	Name:ARHGAP26Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 5

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000145819.15
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:17073 ARHGAP26

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000145819

OpenTargetsⁱ

ENSG00000145819

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	H7C205
PRIDEⁱ	H7C205

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000145819 Expressed in 208 organ(s), highest expression level in blood
ExpressionAtlasⁱ	H7C205 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	H7C205
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150818

GeneTreeⁱ

ENSGT00930000150818

Family and domain databases

InterProⁱ	View protein in InterPro IPR030061 GRAF IPR036028 SH3-like_dom_sf
PANTHERⁱ	PTHR12552:SF4 PTHR12552:SF4, 2 hits
SUPFAMⁱ	SSF50044 SSF50044, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show all Align All

H7C205-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
XPNPSPTSPL SPSWPMFSAP SSPMPTSSTS SDSSPVSTPF RKAKALYACK 
        60         70         80         90 
AEHDSELSFT AGTVFDTECP SASTAIFTAT PKLRAPPPLT WALPLAA

Length:97

Mass (Da):10,094

Last modified:June 20, 2018 - v2

Checksum:ⁱB990F3B86BA59FC1

GO

Computationally mapped potential isoform sequencesⁱ

There are 11 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name	Protein names	Gene names	Length	Annotation

	Q9UNA1	RHG26_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26)	ARHGAP26 GRAF, KIAA0621, OPHN1L	814	Annotation score:
	A0A2R8YGB3	A0A2R8YGB3_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	686	Annotation score:
	H0Y835	H0Y835_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	294	Annotation score:
	H0Y4P9	H0Y4P9_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	388	Annotation score:
	A0A2R8Y5C0	A0A2R8Y5C0_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	338	Annotation score:
	H7BZZ0	H7BZZ0_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	97	Annotation score:
	A0A2R8YDK5	A0A2R8YDK5_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	161	Annotation score:
	C9J6V4	C9J6V4_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	91	Annotation score:
	H7C3P8	H7C3P8_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	127	Annotation score:
	H7C1J1	H7C1J1_HUMAN	Rho GTPase-activating protein 26 Rho GTPase-activating protein 26	ARHGAP26	127	Annotation score:
There is more potential isoformShow all

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC004782 Genomic DNA No translation available. AC005348 Genomic DNA No translation available. AC005574 Genomic DNA No translation available. AC008533 Genomic DNA No translation available. AC012630 Genomic DNA No translation available. KC877124 Genomic DNA No translation available. KC877138 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC004782 Genomic DNA No translation available.
AC005348 Genomic DNA No translation available.
AC005574 Genomic DNA No translation available.
AC008533 Genomic DNA No translation available.
AC012630 Genomic DNA No translation available.
KC877124 Genomic DNA No translation available.
KC877138 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000425417; ENSP00000403388; ENSG00000145819
UCSC genome browser More...UCSCⁱ	uc063ify.1 human

Protein	Similar proteins		Species	Score	Length	Source
H7C205	ARHGAP26 isoform 7 (Fragment)		PONAB		97	UniRef90_H7C205

Protein	Similar proteins		Species	Score	Length	Source
H7C205	ARHGAP26 isoform 7 (Fragment)		PONAB		97	UniRef50_H7C205
Uncharacterized protein (Fragment)		MICSU		100
Rho GTPase-activating protein 10 (Fragment)		OPHHA		87
UPI0007B7D4A3		Sinocyclocheilus rhinocerous		102
UPI0008FA072C		CYPCA		100
+2

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC004782 Genomic DNA No translation available. AC005348 Genomic DNA No translation available. AC005574 Genomic DNA No translation available. AC008533 Genomic DNA No translation available. AC012630 Genomic DNA No translation available. KC877124 Genomic DNA No translation available. KC877138 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC004782 Genomic DNA No translation available.
AC005348 Genomic DNA No translation available.
AC005574 Genomic DNA No translation available.
AC008533 Genomic DNA No translation available.
AC012630 Genomic DNA No translation available.
KC877124 Genomic DNA No translation available.
KC877138 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	H7C205
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlasⁱ	H7C205
PRIDEⁱ	H7C205

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000425417; ENSP00000403388; ENSG00000145819
UCSCⁱ	uc063ify.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000145819.15
HGNCⁱ	HGNC:17073 ARHGAP26
OpenTargetsⁱ	ENSG00000145819
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

GeneTreeⁱ	ENSGT00930000150818

GeneTreeⁱ

ENSGT00930000150818

Miscellaneous databases

ChiTaRSⁱ	ARHGAP26 human

ChiTaRSⁱ

ARHGAP26 human

Gene expression databases

Bgeeⁱ	ENSG00000145819 Expressed in 208 organ(s), highest expression level in blood
ExpressionAtlasⁱ	H7C205 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR030061 GRAF IPR036028 SH3-like_dom_sf
PANTHERⁱ	PTHR12552:SF4 PTHR12552:SF4, 2 hits
SUPFAMⁱ	SSF50044 SSF50044, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H7C205_HUMAN
Accessionⁱ	H7C205Primary (citable) accession number: H7C205
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 18, 2012
	Last sequence update:	June 20, 2018
	Last modified:	November 7, 2018
	This is version 35 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - H7C205 (H7C205_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Rho GTPase-activating protein 26

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ