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Protein
Submitted name:

Cullin-3

Gene

CUL3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Cullin-3Imported
Gene namesi
Name:CUL3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000036257.12
HGNCiHGNC:2553 CUL3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000036257

PTM / Processingi

Proteomic databases

MaxQBiH7C1L6
PeptideAtlasiH7C1L6
PRIDEiH7C1L6

Expressioni

Gene expression databases

BgeeiENSG00000036257 Expressed in 230 organ(s), highest expression level in sperm
ExpressionAtlasiH7C1L6 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH7C1L6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 191CullinInterPro annotationAdd BLAST137

Phylogenomic databases

eggNOGiKOG2167 Eukaryota
COG5647 LUCA
GeneTreeiENSGT00760000119212

Family and domain databases

InterProiView protein in InterPro
IPR001373 Cullin_N
IPR016159 Cullin_repeat-like_dom_sf
PfamiView protein in Pfam
PF00888 Cullin, 1 hit
SUPFAMiSSF74788 SSF74788, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

H7C1L6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XVESDKSQGQ SSQGENDLNG SGKVVYKRCR GIMFSKRKLR YTEMTMDEKY
60 70 80 90 100
VNSIWDLLKN AIQEIQRKNN SGLSFEELYR NAYTMVLHKH GEKLYTGLRE
110 120 130 140 150
VVTEHLINKV REDVLNSLNN NFLQTLNQAW NDHQTAMVMI RDILMYMDRV
160 170 180 190
YVQQNNVENV YNLGLIIFRD QVVRYGCIRD HLRQTLLDMI AR
Length:192
Mass (Da):22,654
Last modified:April 18, 2012 - v1
Checksum:i1F3539C1777F216C
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q13618CUL3_HUMAN
Cullin-3
CUL3 KIAA0617
768Annotation score:
H7C399H7C399_HUMAN
Cullin-3
CUL3
111Annotation score:
A0A087WTG3A0A087WTG3_HUMAN
Cullin-3
CUL3
342Annotation score:
H7C1J0H7C1J0_HUMAN
Cullin-3
CUL3
43Annotation score:
A0A087X1R9A0A087X1R9_HUMAN
Cullin-3
CUL3
55Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei192Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073052 Genomic DNA No translation available.
AC092679 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000436172; ENSP00000400935; ENSG00000036257
UCSCiuc061tdm.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073052 Genomic DNA No translation available.
AC092679 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C1L6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7C1L6
PeptideAtlasiH7C1L6
PRIDEiH7C1L6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000436172; ENSP00000400935; ENSG00000036257
UCSCiuc061tdm.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000036257.12
HGNCiHGNC:2553 CUL3
OpenTargetsiENSG00000036257
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2167 Eukaryota
COG5647 LUCA
GeneTreeiENSGT00760000119212

Miscellaneous databases

ChiTaRSiCUL3 human

Gene expression databases

BgeeiENSG00000036257 Expressed in 230 organ(s), highest expression level in sperm
ExpressionAtlasiH7C1L6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001373 Cullin_N
IPR016159 Cullin_repeat-like_dom_sf
PfamiView protein in Pfam
PF00888 Cullin, 1 hit
SUPFAMiSSF74788 SSF74788, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C1L6_HUMAN
AccessioniPrimary (citable) accession number: H7C1L6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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