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Protein
Submitted name:

Chloride channel protein 1

Gene

CLCN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Chloride channel protein 1Imported
Gene namesi
Name:CLCN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000188037.10
HGNCiHGNC:2019 CLCN1

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188037

PTM / Processingi

Proteomic databases

PRIDEiH7C1F4

Expressioni

Gene expression databases

BgeeiENSG00000188037 Expressed in 74 organ(s), highest expression level in muscle of leg
ExpressionAtlasiH7C1F4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C1F4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0476 Eukaryota
COG0038 LUCA
GeneTreeiENSGT00760000119109

Family and domain databases

Gene3Di1.10.3080.10, 1 hit
InterProiView protein in InterPro
IPR014743 Cl-channel_core
IPR001807 Cl-channel_volt-gated
PfamiView protein in Pfam
PF00654 Voltage_CLC, 1 hit
PRINTSiPR00762 CLCHANNEL
SUPFAMiSSF81340 SSF81340, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

H7C1F4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XISPQAVGSG IPEMKTILRG VVLKEYLTMK AFVAKVVALT AGLGSGIPVG
60 70 80 90 100
KEGPFVHIAS ICAAVLSKFM SVFCGVYEPV PVLQMSTPLS PVAPHGDRAW

AA
Length:102
Mass (Da):10,576
Last modified:April 18, 2012 - v1
Checksum:iEB03DF0AFFA613F3
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P35523CLCN1_HUMAN
Chloride channel protein 1
CLCN1 CLC1
988Annotation score:
H7C0N6H7C0N6_HUMAN
Chloride channel protein 1
CLCN1
76Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073342 Genomic DNA No translation available.
AC093673 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000455478; ENSP00000400027; ENSG00000188037
UCSCiuc064ivl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073342 Genomic DNA No translation available.
AC093673 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C1F4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiH7C1F4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000455478; ENSP00000400027; ENSG00000188037
UCSCiuc064ivl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000188037.10
HGNCiHGNC:2019 CLCN1
OpenTargetsiENSG00000188037
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0476 Eukaryota
COG0038 LUCA
GeneTreeiENSGT00760000119109

Miscellaneous databases

ChiTaRSiCLCN1 human

Gene expression databases

BgeeiENSG00000188037 Expressed in 74 organ(s), highest expression level in muscle of leg
ExpressionAtlasiH7C1F4 baseline and differential

Family and domain databases

Gene3Di1.10.3080.10, 1 hit
InterProiView protein in InterPro
IPR014743 Cl-channel_core
IPR001807 Cl-channel_volt-gated
PfamiView protein in Pfam
PF00654 Voltage_CLC, 1 hit
PRINTSiPR00762 CLCHANNEL
SUPFAMiSSF81340 SSF81340, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C1F4_HUMAN
AccessioniPrimary (citable) accession number: H7C1F4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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