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Protein
Submitted name:

BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

Gene

BNIP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2Imported
Gene namesi
Name:BNIP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000140299.11
HGNCiHGNC:1083 BNIP2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 56HelicalSequence analysisAdd BLAST20
Transmembranei68 – 89HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000140299

PTM / Processingi

Proteomic databases

MaxQBiH7C096
PeptideAtlasiH7C096
PRIDEiH7C096

Expressioni

Gene expression databases

BgeeiENSG00000140299 Expressed in 227 organ(s), highest expression level in leukocyte
ExpressionAtlasiH7C096 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C096
SMRiH7C096
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 182CRAL-TRIOInterPro annotationAdd BLAST158

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili174 – 194Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00420000029688

Family and domain databases

CDDicd00170 SEC14, 1 hit
Gene3Di3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR022181 Bcl2-/adenovirus-E1B
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
PfamiView protein in Pfam
PF12496 BNIP2, 1 hit
PF13716 CRAL_TRIO_2, 1 hit
SMARTiView protein in SMART
SM00516 SEC14, 1 hit
SUPFAMiSSF52087 SSF52087, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

H7C096-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
EKEDGRRWRM FRIGEQDHRV DMKAIEPYKK VISHGGYYGD GLNAIVVFAV
60 70 80 90 100
CFMPESSQPN YRYLMDNLFK YVIGTLELLV AENYMIVYLN GATTRRKMPS
110 120 130 140 150
LGWLRKCYQQ IDRRLRKNLK SLIIVHPSWF IRTLLAVTRP FISSKFSQKI
160 170 180 190 200
RYVFNLAELA ELVPMEYVGI PECIKQYEEE KFKKKQKRVD QELNGKQDEP

KNEQ
Length:204
Mass (Da):24,225
Last modified:April 18, 2012 - v1
Checksum:i525CD0471A115435
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q12982BNIP2_HUMAN
BCL2/adenovirus E1B 19 kDa protein-...
BNIP2 NIP2
314Annotation score:
J3KN59J3KN59_HUMAN
BCL2/adenovirus E1B 19 kDa protein-...
BNIP2
435Annotation score:
H7C142H7C142_HUMAN
BCL2/adenovirus E1B 19 kDa protein-...
BNIP2
87Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092755 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000439052; ENSP00000393644; ENSG00000140299
UCSCiuc059jvw.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092755 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C096
SMRiH7C096
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7C096
PeptideAtlasiH7C096
PRIDEiH7C096

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000439052; ENSP00000393644; ENSG00000140299
UCSCiuc059jvw.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000140299.11
HGNCiHGNC:1083 BNIP2
OpenTargetsiENSG00000140299
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00420000029688

Miscellaneous databases

ChiTaRSiBNIP2 human

Gene expression databases

BgeeiENSG00000140299 Expressed in 227 organ(s), highest expression level in leukocyte
ExpressionAtlasiH7C096 baseline and differential

Family and domain databases

CDDicd00170 SEC14, 1 hit
Gene3Di3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR022181 Bcl2-/adenovirus-E1B
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
PfamiView protein in Pfam
PF12496 BNIP2, 1 hit
PF13716 CRAL_TRIO_2, 1 hit
SMARTiView protein in SMART
SM00516 SEC14, 1 hit
SUPFAMiSSF52087 SSF52087, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C096_HUMAN
AccessioniPrimary (citable) accession number: H7C096
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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