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Protein
Submitted name:

Macrophage-stimulating protein receptor

Gene

MST1R

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Macrophage-stimulating protein receptorImported
Gene namesi
Name:MST1RImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000164078.12
HGNCiHGNC:7381 MST1R

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 29HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164078

PTM / Processingi

Proteomic databases

PeptideAtlasiH7C074
PRIDEiH7C074

Expressioni

Gene expression databases

BgeeiENSG00000164078 Expressed in 125 organ(s), highest expression level in mucosa of transverse colon
ExpressionAtlasiH7C074 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C074
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 285Protein kinaseInterPro annotationAdd BLAST226

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1095 Eukaryota
KOG3610 Eukaryota
ENOG410XRIK LUCA
GeneTreeiENSGT00810000125384

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS
IPR020635 Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR00109 TYRKINASE
SMARTiView protein in SMART
SM00219 TyrKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

H7C074-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XQSTLLGILL PLLLLVAALA TALVFSYWWR RKQLVLPPNL NDLASLDQTA
60 70 80 90 100
GATPLPILYS GSDYRSGLGH FGVVYHGEYI DQAQNRIQCA IKSLSRITEM
110 120 130 140 150
QQVEAFLREG LLMRGLNHPN VLALIGIMLP PEGLPHVLLP YMCHGDLLQF
160 170 180 190 200
IRSPQRNPTV KDLISFGLQV ARGMEYLAEQ KFVHRDLAAR NCMLDESFTV
210 220 230 240 250
KVADFGLARD ILDREYYSVQ QHRHARLPVK WMALESLQTY RFTTKSDVWS
260 270 280
FGVLLWELLT RGAPPYRHID PFDLTHFLAQ GRRLP
Length:285
Mass (Da):32,443
Last modified:October 29, 2014 - v2
Checksum:i623F279D3F6F3B9C
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q04912RON_HUMAN
Macrophage-stimulating protein rece...
MST1R PTK8, RON
1,400Annotation score:
A0A087WZQ8A0A087WZQ8_HUMAN
Macrophage-stimulating protein rece...
MST1R
574Annotation score:
J3KQS7J3KQS7_HUMAN
Macrophage-stimulating protein rece...
MST1R
1,032Annotation score:
H2E272H2E272_HUMAN
MST1R variant RON30
MST1R
254Annotation score:
H7C3Z8H7C3Z8_HUMAN
Macrophage-stimulating protein rece...
MST1R
270Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei285Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105935 Genomic DNA No translation available.
KC876868 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000434765; ENSP00000393294; ENSG00000164078
UCSCiuc062jyw.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105935 Genomic DNA No translation available.
KC876868 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C074
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH7C074
PRIDEiH7C074

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000434765; ENSP00000393294; ENSG00000164078
UCSCiuc062jyw.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000164078.12
HGNCiHGNC:7381 MST1R
OpenTargetsiENSG00000164078
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1095 Eukaryota
KOG3610 Eukaryota
ENOG410XRIK LUCA
GeneTreeiENSGT00810000125384

Miscellaneous databases

ChiTaRSiMST1R human

Gene expression databases

BgeeiENSG00000164078 Expressed in 125 organ(s), highest expression level in mucosa of transverse colon
ExpressionAtlasiH7C074 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS
IPR020635 Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR00109 TYRKINASE
SMARTiView protein in SMART
SM00219 TyrKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C074_HUMAN
AccessioniPrimary (citable) accession number: H7C074
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: October 29, 2014
Last modified: September 12, 2018
This is version 41 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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