UniProtKB - H7C053 (H7C053_HUMAN)
Protein
Polyglutamine tract-binding protein 1
Gene
PQBP1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- innate immune response Source: UniProtKB-KW
- mRNA processing Source: UniProtKB-KW
- RNA splicing Source: UniProtKB-KW
Keywordsi
Biological process | Immunity, Innate immunityARBA annotation, mRNA processing, mRNA splicingARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Polyglutamine tract-binding protein 1ARBA annotationAlternative name(s): Polyglutamine-binding protein 1ARBA annotation |
Gene namesi | Name:PQBP1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9330, PQBP1 |
VEuPathDBi | HostDB:ENSG00000102103.15 |
Subcellular locationi
Nucleus
- Nucleus speckle ARBA annotation
Other locations
- Cytoplasmic granule ARBA annotation
Nucleus
- nuclear speck Source: UniProtKB-SubCell
PTM / Processingi
Proteomic databases
MaxQBi | H7C053 |
PeptideAtlasi | H7C053 |
PRIDEi | H7C053 |
ProteomicsDBi | 44182 |
Expressioni
Gene expression databases
Bgeei | ENSG00000102103, Expressed in female gonad and 243 other tissues |
ExpressionAtlasi | H7C053, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 69 | WWInterPro annotationAdd BLAST | 35 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 84 – 150 | DisorderedSequence analysisAdd BLAST | 67 |
Phylogenomic databases
GeneTreei | ENSGT00950000183102 |
Family and domain databases
CDDi | cd00201, WW, 1 hit |
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR036249, Thioredoxin-like_sf IPR001202, WW_dom IPR036020, WW_dom_sf |
SMARTi | View protein in SMART SM00456, WW, 1 hit |
SUPFAMi | SSF51045, SSF51045, 1 hit |
PROSITEi | View protein in PROSITE PS50020, WW_DOMAIN_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
H7C053-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XIATYLLHLL VQPEEEIIAE DYDDDPVDYE ATRLEGLPPS WYKVFDPSCG
60 70 80 90 100
LPYYWNADTD LVSWLSPHDP NSVVTKSAKK LRSSNAAVSR KDEELDPMDP
110 120 130 140 150
SSYSDAPRGT WSTGLPKRNE AKTGADTTAA GPLFQQRPYP SPGAVLRANA
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO60828 | PQBP1_HUMAN | Polyglutamine-binding protein 1 | PQBP1 NPW38, JM26 | 265 | Annotation score: | ||
A0A5H1ZRR1 | A0A5H1ZRR1_HUMAN | Polyglutamine-binding protein 1 | PQBP1 | 213 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 150 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC233300 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000456306; ENSP00000393013; ENSG00000102103 |
UCSCi | uc064zcb.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC233300 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
MaxQBi | H7C053 |
PeptideAtlasi | H7C053 |
PRIDEi | H7C053 |
ProteomicsDBi | 44182 |
Protocols and materials databases
Antibodypediai | 454, 151 antibodies |
Genome annotation databases
Ensembli | ENST00000456306; ENSP00000393013; ENSG00000102103 |
UCSCi | uc064zcb.1, human |
Organism-specific databases
HGNCi | HGNC:9330, PQBP1 |
OpenTargetsi | ENSG00000102103 |
VEuPathDBi | HostDB:ENSG00000102103.15 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00950000183102 |
Miscellaneous databases
ChiTaRSi | PQBP1, human |
Gene expression databases
Bgeei | ENSG00000102103, Expressed in female gonad and 243 other tissues |
ExpressionAtlasi | H7C053, baseline and differential |
Family and domain databases
CDDi | cd00201, WW, 1 hit |
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR036249, Thioredoxin-like_sf IPR001202, WW_dom IPR036020, WW_dom_sf |
SMARTi | View protein in SMART SM00456, WW, 1 hit |
SUPFAMi | SSF51045, SSF51045, 1 hit |
PROSITEi | View protein in PROSITE PS50020, WW_DOMAIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H7C053_HUMAN | |
Accessioni | H7C053Primary (citable) accession number: H7C053 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | February 10, 2021 | |
This is version 54 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |