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Protein
Submitted name:

Bromodomain-containing protein 8

Gene

BRD8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Bromodomain-containing protein 8Imported
Gene namesi
Name:BRD8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000112983.17
HGNCiHGNC:19874 BRD8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000112983

PTM / Processingi

Proteomic databases

MaxQBiH7C026
PeptideAtlasiH7C026
PRIDEiH7C026

Expressioni

Gene expression databases

BgeeiENSG00000112983 Expressed in 233 organ(s), highest expression level in testis
ExpressionAtlasiH7C026 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7C026
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini226 – 296BromoInterPro annotationAdd BLAST71

Keywords - Domaini

BromodomainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IF07 Eukaryota
ENOG410Y97J LUCA
GeneTreeiENSGT00530000064262

Family and domain databases

CDDicd05507 Bromo_brd8_like, 1 hit
Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR037966 Brd8_Bromo_dom
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
PROSITEiView protein in PROSITE
PS50014 BROMODOMAIN_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 14 potential isoforms that are computationally mapped.Show allAlign All

H7C026-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DLDVGNWRET EDPEAEELEE SSPEREPSEL LVGDGGSEES QEAARKASHQ
60 70 80 90 100
NLLHFLSEVA YLMEPLCISS NESSEGCCPP SGTRQEGREI KASEGERELC
110 120 130 140 150
RETEELSAKG DPLVAEKPLG ENGKPEVASA PSVICTVQGL LTESEEGEAQ
160 170 180 190 200
QESKGEDQGE VYVSEMEDQP PSGECDDAFN IKETPLVDTL FSHATSSKLT
210 220 230 240 250
DLSQDDPVQD HLLFKKTLLP VWKMIASHRF SSPFLKPVSE RQAPGYKDVV
260 270 280 290 300
KRPMDLTSLK RNLSKGRIRT MAQFLRDLML MFQNAVMYND SDHHVYHMAV
310 320 330
EMRQEVLEQI QVLYADTCSL WNLDFRTPMR IKVISR
Length:336
Mass (Da):37,735
Last modified:April 18, 2012 - v1
Checksum:iA9994D3D2AD930DD
GO

Computationally mapped potential isoform sequencesi

There are 14 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9H0E9BRD8_HUMAN
Bromodomain-containing protein 8
BRD8 SMAP, SMAP2
1,235Annotation score:
B5MCW3B5MCW3_HUMAN
Bromodomain-containing protein 8
BRD8
878Annotation score:
H7C128H7C128_HUMAN
Bromodomain-containing protein 8
BRD8
857Annotation score:
H7C127H7C127_HUMAN
Bromodomain-containing protein 8
BRD8
892Annotation score:
H7C179H7C179_HUMAN
Bromodomain-containing protein 8
BRD8
861Annotation score:
H0YA84H0YA84_HUMAN
Bromodomain-containing protein 8
BRD8
195Annotation score:
H7C2P4H7C2P4_HUMAN
Bromodomain-containing protein 8
BRD8
187Annotation score:
F8WBH2F8WBH2_HUMAN
Bromodomain-containing protein 8
BRD8
79Annotation score:
D6RID0D6RID0_HUMAN
Bromodomain-containing protein 8
BRD8
48Annotation score:
F8WDX5F8WDX5_HUMAN
Bromodomain-containing protein 8
BRD8
39Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106752 Genomic DNA No translation available.
AC109442 Genomic DNA No translation available.
AC113382 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000427976; ENSP00000392646; ENSG00000112983
UCSCiuc063hja.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106752 Genomic DNA No translation available.
AC109442 Genomic DNA No translation available.
AC113382 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7C026
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7C026
PeptideAtlasiH7C026
PRIDEiH7C026

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000427976; ENSP00000392646; ENSG00000112983
UCSCiuc063hja.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000112983.17
HGNCiHGNC:19874 BRD8
OpenTargetsiENSG00000112983
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IF07 Eukaryota
ENOG410Y97J LUCA
GeneTreeiENSGT00530000064262

Miscellaneous databases

ChiTaRSiBRD8 human

Gene expression databases

BgeeiENSG00000112983 Expressed in 233 organ(s), highest expression level in testis
ExpressionAtlasiH7C026 baseline and differential

Family and domain databases

CDDicd05507 Bromo_brd8_like, 1 hit
Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR037966 Brd8_Bromo_dom
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
PROSITEiView protein in PROSITE
PS50014 BROMODOMAIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7C026_HUMAN
AccessioniPrimary (citable) accession number: H7C026
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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