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Protein
Submitted name:

Mitochondrial chaperone BCS1

Gene

BCS1L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial chaperone BCS1Imported
Gene namesi
Name:BCS1LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000074582.12
HGNCiHGNC:1020 BCS1L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000074582

PTM / Processingi

Proteomic databases

MaxQBiH7BZF6
PeptideAtlasiH7BZF6
PRIDEiH7BZF6

Expressioni

Gene expression databases

BgeeiENSG00000074582 Expressed in 215 organ(s), highest expression level in body of pancreas
ExpressionAtlasiH7BZF6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7BZF6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 120AAAInterPro annotationAdd BLAST117

Phylogenomic databases

eggNOGiKOG0743 Eukaryota
COG0465 LUCA
GeneTreeiENSGT00390000005415

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR027243 BCS1
IPR027417 P-loop_NTPase
PANTHERiPTHR23070:SF17 PTHR23070:SF17, 1 hit
PfamiView protein in Pfam
PF00004 AAA, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

H7BZF6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XIPYRRGYLL YGPPGCGKSS FITALAGELE HSICLLSLTD SSLSDDRLNH
60 70 80 90 100
LLSVAPQQSL VLLEDVDAAF LSRDLAVENP VKYQGLGRLT FSGLLNALDG
110 120
VASTEARIVF MTTNHVDRHL P
Length:121
Mass (Da):13,136
Last modified:April 18, 2012 - v1
Checksum:iDA1D4DA857F3320F
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y276BCS1_HUMAN
Mitochondrial chaperone BCS1
BCS1L BCS1
419Annotation score:
H7C492H7C492_HUMAN
Mitochondrial chaperone BCS1
BCS1L
201Annotation score:
C9JAS4C9JAS4_HUMAN
Mitochondrial chaperone BCS1
BCS1L
110Annotation score:
C9J8G3C9J8G3_HUMAN
Mitochondrial chaperone BCS1
BCS1L
206Annotation score:
C9J4Q9C9J4Q9_HUMAN
Mitochondrial chaperone BCS1
BCS1L
76Annotation score:
A0A2R8Y7T3A0A2R8Y7T3_HUMAN
Mitochondrial chaperone BCS1
BCS1L
153Annotation score:
C9J1S9C9J1S9_HUMAN
Mitochondrial chaperone BCS1
BCS1L
150Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009974 Genomic DNA No translation available.
AC079810 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000436603; ENSP00000389402; ENSG00000074582
UCSCiuc061sno.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009974 Genomic DNA No translation available.
AC079810 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7BZF6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7BZF6
PeptideAtlasiH7BZF6
PRIDEiH7BZF6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000436603; ENSP00000389402; ENSG00000074582
UCSCiuc061sno.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000074582.12
HGNCiHGNC:1020 BCS1L
OpenTargetsiENSG00000074582
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0743 Eukaryota
COG0465 LUCA
GeneTreeiENSGT00390000005415

Gene expression databases

BgeeiENSG00000074582 Expressed in 215 organ(s), highest expression level in body of pancreas
ExpressionAtlasiH7BZF6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR027243 BCS1
IPR027417 P-loop_NTPase
PANTHERiPTHR23070:SF17 PTHR23070:SF17, 1 hit
PfamiView protein in Pfam
PF00004 AAA, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7BZF6_HUMAN
AccessioniPrimary (citable) accession number: H7BZF6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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