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Protein
Submitted name:

Solute carrier family 22 member 5

Gene

SLC22A5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 22 member 5Imported
Gene namesi
Name:SLC22A5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000197375.12
HGNCiHGNC:10969 SLC22A5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei65 – 83HelicalSequence analysisAdd BLAST19
Transmembranei95 – 112HelicalSequence analysisAdd BLAST18
Transmembranei118 – 140HelicalSequence analysisAdd BLAST23
Transmembranei152 – 176HelicalSequence analysisAdd BLAST25
Transmembranei182 – 200HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197375

PTM / Processingi

Proteomic databases

PeptideAtlasiH7BZC0
PRIDEiH7BZC0

Expressioni

Gene expression databases

BgeeiENSG00000197375 Expressed in 189 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasiH7BZC0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7BZC0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 240MFSInterPro annotationAdd BLAST240

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118852

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H7BZC0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DVDLGQLEQE SCLDGWEFSQ DVYLSTIVTE QDSGAYNAMK NRMGKKPALC
60 70 80 90 100
LPAQWNLVCE DDWKAPLTIS LFFVGVLLGS FISGQLSDRF GRKNVLFVTM
110 120 130 140 150
GMQTGFSFLQ IFSKNFEMFV VLFVLVGMGQ ISNYVAAFVL GTEILGKSVR
160 170 180 190 200
IIFSTLGVCI FYAFGYMVLP LFAYFIRDWR MLLVALTMPG VLCVALWWFI
210 220 230 240
PESPRWLISQ GRFEEAEVII RKAAKANGIV VPSTIFDPSE
Length:240
Mass (Da):26,988
Last modified:April 18, 2012 - v1
Checksum:iE684356687DD9CF1
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O76082S22A5_HUMAN
Solute carrier family 22 member 5
SLC22A5 OCTN2
557Annotation score:
H7C1R8H7C1R8_HUMAN
Solute carrier family 22 member 5
SLC22A5
136Annotation score:
F8WCC9F8WCC9_HUMAN
Solute carrier family 22 member 5
SLC22A5
141Annotation score:
H7BZF0H7BZF0_HUMAN
Solute carrier family 22 member 5
SLC22A5
37Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei240Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC118464 Genomic DNA No translation available.
KF457996 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000415928; ENSP00000388838; ENSG00000197375
UCSCiuc063guj.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC118464 Genomic DNA No translation available.
KF457996 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7BZC0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH7BZC0
PRIDEiH7BZC0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000415928; ENSP00000388838; ENSG00000197375
UCSCiuc063guj.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000197375.12
HGNCiHGNC:10969 SLC22A5
OpenTargetsiENSG00000197375
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118852

Miscellaneous databases

ChiTaRSiSLC22A5 human

Gene expression databases

BgeeiENSG00000197375 Expressed in 189 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasiH7BZC0 baseline and differential

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7BZC0_HUMAN
AccessioniPrimary (citable) accession number: H7BZC0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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