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UniProtKB - H7BZ55 (CRCC2_HUMAN)
Protein
Ciliary rootlet coiled-coil protein 2
Gene
CROCC2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Ciliary rootlet coiled-coil protein 2Curated |
Gene namesi | Name:CROCC2Imported |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:51677, CROCC2 |
neXtProti | NX_H7BZ55 |
VEuPathDBi | HostDB:ENSG00000226321 |
Pathology & Biotechi
Miscellaneous databases
Pharosi | H7BZ55, Tdark |
Genetic variation databases
BioMutai | CROCC2 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000422613 | 1 – 1653 | Ciliary rootlet coiled-coil protein 2Add BLAST | 1653 |
Proteomic databases
jPOSTi | H7BZ55 |
MassIVEi | H7BZ55 |
PaxDbi | H7BZ55 |
PeptideAtlasi | H7BZ55 |
PRIDEi | H7BZ55 |
PTM databases
PhosphoSitePlusi | H7BZ55 |
Expressioni
Gene expression databases
Bgeei | ENSG00000226321, Expressed in right uterine tube and 78 other tissues |
Organism-specific databases
HPAi | ENSG00000226321, Tissue enhanced (choroid plexus, fallopian tube) |
Interactioni
Protein-protein interaction databases
IntActi | H7BZ55, 2 interactors |
STRINGi | 9606.ENSP00000397968 |
Miscellaneous databases
RNActi | H7BZ55, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 57 | DisorderedSequence analysisAdd BLAST | 57 | |
Regioni | 367 – 396 | DisorderedSequence analysisAdd BLAST | 30 | |
Regioni | 1302 – 1356 | DisorderedSequence analysisAdd BLAST | 55 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 86 – 145 | Sequence analysisAdd BLAST | 60 | |
Coiled coili | 310 – 351 | Sequence analysisAdd BLAST | 42 | |
Coiled coili | 423 – 1215 | Sequence analysisAdd BLAST | 793 | |
Coiled coili | 1361 – 1570 | Sequence analysisAdd BLAST | 210 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 21 | Polar residuesSequence analysisAdd BLAST | 21 | |
Compositional biasi | 1307 – 1338 | Polar residuesSequence analysisAdd BLAST | 32 |
Sequence similaritiesi
Belongs to the rootletin family.Curated
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | ENOG502QQV3, Eukaryota |
HOGENOMi | CLU_000920_1_0_1 |
InParanoidi | H7BZ55 |
i Sequence
Sequence statusi: Complete.
H7BZ55-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSASSEPGN GDASQQPLLG LDTVIQRLED TILSPTASRE DRALTVRGEG
60 70 80 90 100
RQASPTPVPT RIREIVAGSL SEEPPQAGVQ EPTATVARVQ EENELLQEEL
110 120 130 140 150
TRLGDLLAQA SAERDELASR CRVVSEQLQA RLETTEAQLR RSELEHSVDL
160 170 180 190 200
EEALGRLEAA EERSTGLCQV NALLREQLEH MKKANDALGR ELAGMTGSVQ
210 220 230 240 250
RLQGELELRR WAQRQTRSGG LGQPRDLLLL WRQAVVLGTD LAELRVATER
260 270 280 290 300
GLADLQADTA RTARRLHTAC LNLDSNLRLS ASSTASTLGQ QLRDKAGEML
310 320 330 340 350
QLQGRWDAEK VALQARLSEQ TLLVEKLTEQ NEQKAKTIAA LRTDLQNLVA
360 370 380 390 400
QEDARCLELA GSSITELGEP RRPLRSPQRA TSPHQGASPP HICSPATLDP
410 420 430 440 450
ALQAMRAAIE RRWRREQELC LQLKSSQALV ASLQEQLSES RRELWAAQKL
460 470 480 490 500
QQERAREQAR EREALRGQLE AQRLEVQQCR ASCKLLGREK AALEMVVEEL
510 520 530 540 550
KGKADAADAE KQGLEAEAAE LQRSLLLQAE RREELALRRE RSCRALETSQ
560 570 580 590 600
GRLQQLEEKV SGLREELASV REALSTAQLQ RDVVESEREG LRSALARAEC
610 620 630 640 650
SNADLELLVR RLKSEGVEQR DSLAAMAALM EGLAQDKSAL NHLALQLEQE
660 670 680 690 700
RDQLREQRKT LEQERARAGE QLAQAEQQLA LERAERRGLQ QACGRLEQRQ
710 720 730 740 750
EQLEGQAALL GREKAQLQEQ VGQVTCQKQA LEEQLAQSLQ DQEAQMGTLQ
760 770 780 790 800
QALQGKDALS EERAQLLAKQ EALERQGRLA AEEAADLRVE RDSLESSLLE
810 820 830 840 850
AQQLATKLQE QLEEEARSAG LARQALQVEM EQLQSDWEVQ EMKLRQDTVR
860 870 880 890 900
LQRQVAQQER EAQRALESQA LAHREALAQL QREKETLSLT LAEEKEVARC
910 920 930 940 950
QLEQEKELVT KSAAEREALK GEIQSLKQER DESLLQLEHK MQQALSLKET
960 970 980 990 1000
ERSLLSEELS RARRTLERVQ QEAQSQQEQA QATISATTEE LKALQAQFED
1010 1020 1030 1040 1050
AITAHQRETT ALRESLQDLA AERGDVEREA ERLRAQLTVA QEGLAALRQE
1060 1070 1080 1090 1100
LQGVEESREG LHREAQEARR ALSDEAREKD VLLLFNSELR ATICRAEQEK
1110 1120 1130 1140 1150
ASFKRSKEEK EQKLLILEEA QAALQQEASA LRAHLWELEQ AGGDARQELR
1160 1170 1180 1190 1200
ELHRQVRTLK AENQRRSGEA HELQAQCSQE VLELRRQAAK AEAKHEGARK
1210 1220 1230 1240 1250
EVLGLQRKLA EVEAAGEAHG QRLQEHLRES RGAEQTLRAE LHSVTRKLQE
1260 1270 1280 1290 1300
ASGVADALQA RLDQACHRIH SLEQELAQAE GARQDAEAQL GRLCSTLRRG
1310 1320 1330 1340 1350
LGLQRQSPWA SPEQPGSPTK GSDSSQALPG QQGTSPPARP HSPLRWPSPT
1360 1370 1380 1390 1400
PGGRSSELMD VATVQDILRD FVQKLREAQR ERDDSRIQMA TLSSRLSEAE
1410 1420 1430 1440 1450
CRCARAQSRV GQLQKALAEA EEGQRRVEGA LSSARAARAL QKEALRRLEL
1460 1470 1480 1490 1500
EHLASVRAAG QEKRRLQEQL ETLRQALEES RRHSQGLAKQ GKLLEEQLTN
1510 1520 1530 1540 1550
LEHRCQKAEV SLEPLRQMEQ ETLKREEDVA RLGAEKEQLD QSLNSLHQEV
1560 1570 1580 1590 1600
DGALRQNQQL QAQMTEMEQA HTQRLQDLTA QHQRDLATEA ERLHGARPQA
1610 1620 1630 1640 1650
TQALESQEWT HQQQVKVLEE QVASLKEQLD QEVQWRQQAH LGQAFQTGHA
QRD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC104809 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000443866; ENSP00000397968; ENSG00000226321 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC104809 Genomic DNA No translation available. |
3D structure databases
SMRi | H7BZ55 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | H7BZ55, 2 interactors |
STRINGi | 9606.ENSP00000397968 |
PTM databases
PhosphoSitePlusi | H7BZ55 |
Genetic variation databases
BioMutai | CROCC2 |
Proteomic databases
jPOSTi | H7BZ55 |
MassIVEi | H7BZ55 |
PaxDbi | H7BZ55 |
PeptideAtlasi | H7BZ55 |
PRIDEi | H7BZ55 |
Protocols and materials databases
Antibodypediai | 62332, 3 antibodies from 3 providers |
Genome annotation databases
Ensembli | ENST00000443866; ENSP00000397968; ENSG00000226321 |
Organism-specific databases
GeneCardsi | CROCC2 |
HGNCi | HGNC:51677, CROCC2 |
HPAi | ENSG00000226321, Tissue enhanced (choroid plexus, fallopian tube) |
neXtProti | NX_H7BZ55 |
VEuPathDBi | HostDB:ENSG00000226321 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QQV3, Eukaryota |
HOGENOMi | CLU_000920_1_0_1 |
InParanoidi | H7BZ55 |
Enzyme and pathway databases
PathwayCommonsi | H7BZ55 |
SignaLinki | H7BZ55 |
Miscellaneous databases
ChiTaRSi | CROCC2, human |
Pharosi | H7BZ55, Tdark |
RNActi | H7BZ55, protein |
Gene expression databases
Bgeei | ENSG00000226321, Expressed in right uterine tube and 78 other tissues |
Family and domain databases
MobiDBi | Search... |
Entry informationi
Entry namei | CRCC2_HUMAN | |
Accessioni | H7BZ55Primary (citable) accession number: H7BZ55 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 26, 2013 |
Last sequence update: | November 13, 2019 | |
Last modified: | February 23, 2022 | |
This is version 62 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 2
Human chromosome 2: entries, gene names and cross-references to MIM - SIMILARITY comments
Index of protein domains and families