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Protein
Submitted name:

Serpin B10

Gene

SERPINB10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Serpin B10Imported
Gene namesi
Name:SERPINB10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000242550.5
HGNCiHGNC:8942 SERPINB10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000242550

PTM / Processingi

Proteomic databases

MaxQBiH7BYS2
PeptideAtlasiH7BYS2
PRIDEiH7BYS2

Expressioni

Gene expression databases

BgeeiENSG00000242550 Expressed in 41 organ(s), highest expression level in bone marrow
ExpressionAtlasiH7BYS2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7BYS2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 261SERPINInterPro annotationAdd BLAST261

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118789

Family and domain databases

InterProiView protein in InterPro
IPR015556 PAI-2
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 2 hits
PTHR11461:SF61 PTHR11461:SF61, 2 hits
PfamiView protein in Pfam
PF00079 Serpin, 2 hits
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

H7BYS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XSVNKLFGEK SASFREEYIR LCQKYYSSEP QAVDFLECAE EARKKINSWV
60 70 80 90 100
KTQTKGKIPN LLPEGSVDGD TRMVLVNAVY FKGKWKTPFE KKLNGLYPFR
110 120 130 140 150
VNSAQRTPVQ MMYLREKLNI GYIEDLKAQI LELPYAGDVS MFLLLPDEIA
160 170 180 190 200
DVSTGLELLE SEITYDKLNK WTSKDKMAED EVELKVSQLF SHNLLLQEQI
210 220 230 240 250
ANSAPVGENK VSSMDSLATS INQFALELSK KLAESAQGKN IFFSSWSIST
260 270 280
SLTIVYLGAK GTTAAQMAQV LQFNRDQGVK
Length:280
Mass (Da):31,535
Last modified:April 18, 2012 - v1
Checksum:i46A8CEB2185AF960
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P48595SPB10_HUMAN
Serpin B10
SERPINB10 PI10
397Annotation score:
H7C004H7C004_HUMAN
Serpin B10
SERPINB10
253Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei280Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009802 Genomic DNA No translation available.
AC072051 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000397996; ENSP00000381082; ENSG00000242550
UCSCiuc060pwl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009802 Genomic DNA No translation available.
AC072051 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7BYS2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7BYS2
PeptideAtlasiH7BYS2
PRIDEiH7BYS2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000397996; ENSP00000381082; ENSG00000242550
UCSCiuc060pwl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000242550.5
HGNCiHGNC:8942 SERPINB10
OpenTargetsiENSG00000242550
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118789

Gene expression databases

BgeeiENSG00000242550 Expressed in 41 organ(s), highest expression level in bone marrow
ExpressionAtlasiH7BYS2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR015556 PAI-2
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 2 hits
PTHR11461:SF61 PTHR11461:SF61, 2 hits
PfamiView protein in Pfam
PF00079 Serpin, 2 hits
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH7BYS2_HUMAN
AccessioniPrimary (citable) accession number: H7BYS2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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