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Protein
Submitted name:

Neurexin-1-beta

Gene

NRXN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Neurexin-1-betaImported
Gene namesi
Name:NRXN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000179915.21
HGNCiHGNC:8008 NRXN1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei68 – 88HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179915

PTM / Processingi

Proteomic databases

PeptideAtlasiH7BYC7
PRIDEiH7BYC7

Expressioni

Gene expression databases

BgeeiENSG00000179915 Expressed in 176 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH7BYC7 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 1054.1mInterPro annotationAdd BLAST19

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3514 Eukaryota
ENOG410XNU6 LUCA
GeneTreeiENSGT00760000118991

Family and domain databases

InterProiView protein in InterPro
IPR037440 Neurexin
IPR003585 Neurexin-like
IPR027789 Syndecan/Neurexin_dom
PANTHERiPTHR44287 PTHR44287, 2 hits
PfamiView protein in Pfam
PF01034 Syndecan, 1 hit
SMARTiView protein in SMART
SM00294 4.1m, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 27 potential isoforms that are computationally mapped.iShow all

H7BYC7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDMRWHCENL QTTDDILVAS AECPSDDEDI DPCEPSSGGL ANPTRAGGRE
60 70 80 90 100
PYPGSAEVIR ESSSTTGMVV GIVAAAALCI LILLYAMYKY RNRDEGSYHV
110 120 130 140
DESRNYISNS AQSNGAVVKE KQPSSAKSSN KNKKNKDKEY YV
Length:142
Mass (Da):15,530
Last modified:May 27, 2015 - v2
Checksum:i70FAE8135BEB82BE
GO

Computationally mapped potential isoform sequencesi

There are 27 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9ULB1NRX1A_HUMAN
Neurexin-1
NRXN1 KIAA0578
1,477Annotation score:
E7ERL8E7ERL8_HUMAN
Neurexin-1-beta
NRXN1
1,507Annotation score:
A0A0D9SEP4A0A0D9SEP4_HUMAN
Neurexin-1-beta
NRXN1
1,496Annotation score:
A0A1D5RMU6A0A1D5RMU6_HUMAN
Neurexin-1-beta
NRXN1
1,499Annotation score:
A0A0R4J2G7A0A0R4J2G7_HUMAN
Neurexin-1-beta
NRXN1
1,495Annotation score:
F8WB18F8WB18_HUMAN
Neurexin-1-beta
NRXN1
851Annotation score:
F5GYC7F5GYC7_HUMAN
Neurexin-1-beta
NRXN1
836Annotation score:
A0A0D9SF36A0A0D9SF36_HUMAN
Neurexin-1-beta
NRXN1
213Annotation score:
A0A0D9SFF4A0A0D9SFF4_HUMAN
Neurexin-1-beta
NRXN1
459Annotation score:
A0A0D9SEM5A0A0D9SEM5_HUMAN
Neurexin-1-beta
NRXN1
469Annotation score:
There are more potential isoformsShow all

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007462 Genomic DNA No translation available.
AC007560 Genomic DNA No translation available.
AC007680 Genomic DNA No translation available.
AC007682 Genomic DNA No translation available.
AC009234 Genomic DNA No translation available.
AC010721 Genomic DNA No translation available.
AC068715 Genomic DNA No translation available.
AC068725 Genomic DNA No translation available.
AC069550 Genomic DNA No translation available.
AC078994 Genomic DNA No translation available.
RefSeqiNP_001307085.1, NM_001320156.3
UniGeneiHs.637685

Genome annotation databases

EnsembliENST00000378262; ENSP00000367510; ENSG00000179915
GeneIDi9378
UCSCiuc010yon.3 human

Similar proteinsi

Entry informationi

Entry nameiH7BYC7_HUMAN
AccessioniPrimary (citable) accession number: H7BYC7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: May 27, 2015
Last modified: September 12, 2018
This is version 43 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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