UniProtKB - H7BY79 (H7BY79_HUMAN)
Protein
Submitted name:
Cadherin-like protein 26
Gene
CDH26
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- calcium ion binding Source: UniProtKB-UniRule
GO - Biological processi
- homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Keywordsi
Ligand | CalciumPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Cadherin-like protein 26Imported |
Gene namesi | Name:CDH26Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:15902, CDH26 |
VEuPathDBi | HostDB:ENSG00000124215.16 |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: UniProtKB-KW
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 203 – 228 | HelicalSequence analysisAdd BLAST | 26 |
Keywords - Cellular componenti
MembranePTM / Processingi
Keywords - PTMi
GlycoproteinARBA annotationProteomic databases
PeptideAtlasi | H7BY79 |
PRIDEi | H7BY79 |
ProteomicsDBi | 43533 |
Expressioni
Gene expression databases
Bgeei | ENSG00000124215, Expressed in bronchial epithelial cell and 140 other tissues |
ExpressionAtlasi | H7BY79, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 92 | CadherinInterPro annotationAdd BLAST | 90 |
Keywords - Domaini
RepeatARBA annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000161589 |
HOGENOMi | CLU_619027_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR039808, Cadherin IPR002126, Cadherin-like_dom IPR015919, Cadherin-like_sf IPR020894, Cadherin_CS |
PANTHERi | PTHR24027, PTHR24027, 1 hit |
Pfami | View protein in Pfam PF00028, Cadherin, 1 hit |
PRINTSi | PR00205, CADHERIN |
SMARTi | View protein in SMART SM00112, CA, 1 hit |
SUPFAMi | SSF49313, SSF49313, 2 hits |
PROSITEi | View protein in PROSITE PS00232, CADHERIN_1, 1 hit PS50268, CADHERIN_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
H7BY79-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XRPGTLLGTF NAMDPDSQIR YELVHDPANW VSVDKNSGVV ITVEPIDRES
60 70 80 90 100
PHVNNSFYVI IIHAVDDGFP PQTATGTLML FLSDINDNVP TLRPRSRYME
110 120 130 140 150
VCESAVHEPL HIEAEDPDLE PFSDPFTFEL DNTWGNAEDT WKLGRNWGQS
160 170 180 190 200
VELLTLRSLP RGNYLVPLFI GDKQGLSQKQ TVHVRICPCA SGLTCVELAD
210 220 230 240 250
AEVGLHVGAL FPVCAAFVAL AVALLFLLRC YFVLEPKRHG CSVSNDEGHQ
260 270 280 290 300
TLVMYNAESK GTSAQTWSDV EGQRPALLIC TAAAGPTQGV KAYPDATMHR
310 320 330 340 350
QLLAPVEGRM AETLNQSKER NRFSLSRGCI IPQGRATAGR GLPQDIYKEM
360 370 380 390 400
MPRRLTQTGK RKHGALARTP SFKKVVYDHK EDEENKAGRK QRSHLFKVMQ
410 420 430 440
LRNEQGGVRV QSAHSPSPLN KKACFPGDYR GESAGGHNCR AVSG
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8IXH8 | CAD26_HUMAN | Cadherin-like protein 26 | CDH26 | 832 | Annotation score: | ||
Q9NTY2 | Q9NTY2_HUMAN | Cadherin-like protein 26 | CDH26 | 80 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL109928 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000370991; ENSP00000360030; ENSG00000124215 |
UCSCi | uc061yfc.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL109928 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | H7BY79 |
PRIDEi | H7BY79 |
ProteomicsDBi | 43533 |
Protocols and materials databases
Antibodypediai | 2400, 148 antibodies |
Genome annotation databases
Ensembli | ENST00000370991; ENSP00000360030; ENSG00000124215 |
UCSCi | uc061yfc.1, human |
Organism-specific databases
HGNCi | HGNC:15902, CDH26 |
OpenTargetsi | ENSG00000124215 |
VEuPathDBi | HostDB:ENSG00000124215.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161589 |
HOGENOMi | CLU_619027_0_0_1 |
Gene expression databases
Bgeei | ENSG00000124215, Expressed in bronchial epithelial cell and 140 other tissues |
ExpressionAtlasi | H7BY79, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR039808, Cadherin IPR002126, Cadherin-like_dom IPR015919, Cadherin-like_sf IPR020894, Cadherin_CS |
PANTHERi | PTHR24027, PTHR24027, 1 hit |
Pfami | View protein in Pfam PF00028, Cadherin, 1 hit |
PRINTSi | PR00205, CADHERIN |
SMARTi | View protein in SMART SM00112, CA, 1 hit |
SUPFAMi | SSF49313, SSF49313, 2 hits |
PROSITEi | View protein in PROSITE PS00232, CADHERIN_1, 1 hit PS50268, CADHERIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H7BY79_HUMAN | |
Accessioni | H7BY79Primary (citable) accession number: H7BY79 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | April 7, 2021 | |
This is version 45 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |