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Entry version 57 (07 Oct 2020)
Sequence version 1 (18 Apr 2012)
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Protein
Submitted name:

CUB and sushi domain-containing protein 1

Gene

CSMD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
CUB and sushi domain-containing protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CSMD1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000183117.18

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14026, CSMD1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2891 – 2912HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000183117

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi34 ↔ 61PROSITE-ProRule annotation
Disulfide bondi380 ↔ 407PROSITE-ProRule annotation
Disulfide bondi758 ↔ 785PROSITE-ProRule annotation
Disulfide bondi2066 ↔ 2093PROSITE-ProRule annotation
Disulfide bondi2124 ↔ 2151PROSITE-ProRule annotation
Disulfide bondi2182 ↔ 2209PROSITE-ProRule annotation
Disulfide bondi2245 ↔ 2272PROSITE-ProRule annotation
Disulfide bondi2303 ↔ 2330PROSITE-ProRule annotation
Disulfide bondi2364 ↔ 2391PROSITE-ProRule annotation
Disulfide bondi2423 ↔ 2450PROSITE-ProRule annotation
Disulfide bondi2541 ↔ 2568PROSITE-ProRule annotation
Disulfide bondi2599 ↔ 2626PROSITE-ProRule annotation
Disulfide bondi2661 ↔ 2688PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
H7BXU2

PRoteomics IDEntifications database

More...
PRIDEi
H7BXU2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
43397

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000183117, Expressed in primary visual cortex and 156 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
H7BXU2, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6 – 63SushiInterPro annotationAdd BLAST58
Domaini65 – 173CUBInterPro annotationAdd BLAST109
Domaini176 – 237SushiInterPro annotationAdd BLAST62
Domaini239 – 347CUBInterPro annotationAdd BLAST109
Domaini352 – 409SushiInterPro annotationAdd BLAST58
Domaini411 – 521CUBInterPro annotationAdd BLAST111
Domaini524 – 583SushiInterPro annotationAdd BLAST60
Domaini585 – 693CUBInterPro annotationAdd BLAST109
Domaini696 – 756SushiInterPro annotationAdd BLAST61
Domaini758 – 867CUBInterPro annotationAdd BLAST110
Domaini870 – 930SushiInterPro annotationAdd BLAST61
Domaini932 – 1040CUBInterPro annotationAdd BLAST109
Domaini1043 – 1104SushiInterPro annotationAdd BLAST62
Domaini1106 – 1214CUBInterPro annotationAdd BLAST109
Domaini1220 – 1281SushiInterPro annotationAdd BLAST62
Domaini1283 – 1391CUBInterPro annotationAdd BLAST109
Domaini1394 – 1453SushiInterPro annotationAdd BLAST60
Domaini1455 – 1563CUBInterPro annotationAdd BLAST109
Domaini1566 – 1625SushiInterPro annotationAdd BLAST60
Domaini1627 – 1738CUBInterPro annotationAdd BLAST112
Domaini1737 – 1798SushiInterPro annotationAdd BLAST62
Domaini1848 – 1910SushiInterPro annotationAdd BLAST63
Domaini1911 – 1972SushiInterPro annotationAdd BLAST62
Domaini1973 – 2037SushiInterPro annotationAdd BLAST65
Domaini2038 – 2095SushiInterPro annotationAdd BLAST58
Domaini2096 – 2153SushiInterPro annotationAdd BLAST58
Domaini2154 – 2211SushiInterPro annotationAdd BLAST58
Domaini2212 – 2274SushiInterPro annotationAdd BLAST63
Domaini2275 – 2332SushiInterPro annotationAdd BLAST58
Domaini2336 – 2393SushiInterPro annotationAdd BLAST58
Domaini2394 – 2452SushiInterPro annotationAdd BLAST59
Domaini2453 – 2512SushiInterPro annotationAdd BLAST60
Domaini2513 – 2570SushiInterPro annotationAdd BLAST58
Domaini2571 – 2628SushiInterPro annotationAdd BLAST58
Domaini2632 – 2690SushiInterPro annotationAdd BLAST59
Domaini2691 – 2750SushiInterPro annotationAdd BLAST60

Keywords - Domaini

SushiPROSITE-ProRule annotationARBA annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155701

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00033, CCP, 26 hits
cd00041, CUB, 10 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.290, 11 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00431, CUB, 10 hits
PF00084, Sushi, 26 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00032, CCP, 26 hits
SM00042, CUB, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49854, SSF49854, 11 hits
SSF57535, SSF57535, 26 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01180, CUB, 10 hits
PS50923, SUSHI, 26 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H7BXU2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XEIEKGGCGD PGIPAYGKRT GSSFLHGDTL TFECPAAFEL VGERVITCQQ
60 70 80 90 100
NNQWSGNKPS CVFSCFFNFT ASSGIILSPN YPEEYGNNMN CVWLIISEPG
110 120 130 140 150
SRIHLIFNDF DVEPQFDFLA VKDDGISDIT VLGTFSGNEV PSQLASSGHI
160 170 180 190 200
VRLEFQSDHS TTGRGFNITY TTFGQNECHD PGIPINGRRF GDRFLLGSSV
210 220 230 240 250
SFHCDDGFVK TQGSESITCI LQDGNVVWSS TVPRCEAPCG GHLTASSGVI
260 270 280 290 300
LPPGWPGYYK DSLHCEWIIE AKPGHSIKIT FDRFQTEVNY DTLEVRDGPA
310 320 330 340 350
SSSPLIGEYH GTQAPQFLIS TGNFMYLLFT TDNSRSSIGF LIHYESVTLE
360 370 380 390 400
SDSCLDPGIP VNGHRHGGDF GIRSTVTFSC DPGYTLSDDE PLVCERNHQW
410 420 430 440 450
NHALPSCDAL CGGYIQGKSG TVLSPGFPDF YPNSLNCTWT IEVSHGKGVQ
460 470 480 490 500
MIFHTFHLES SHDYLLITED GSFSEPVARL TGSVLPHTIK AGLFGNFTAQ
510 520 530 540 550
LRFISDFSIS YEGFNITFSE YDLEPCDDPG VPAFSRRIGF HFGVGDSLTF
560 570 580 590 600
SCFLGYRLEG ATKLTCLGGG RRVWSAPLPR CVAECGASVK GNEGTLLSPN
610 620 630 640 650
FPSNYDNNHE CIYKIETEAG KGIHLRTRSF QLFEGDTLKV YDGKDSSSRP
660 670 680 690 700
LGTFTKNELL GLILNSTSNH LWLEFNTNGS DTDQGFQLTY TSFDLVKCED
710 720 730 740 750
PGIPNYGYRI RDEGHFTDTV VLYSCNPGYA MHGSNTLTCL SGDRRVWDKP
760 770 780 790 800
LPSCIAECGG QIHAATSGRI LSPGYPAPYD NNLHCTWIIE ADPGKTISLH
810 820 830 840 850
FIVFDTEMAH DILKVWDGPV DSDILLKEWS GSALPEDIHS TFNSLTLQFD
860 870 880 890 900
SDFFISKSGF SIQFSTSIAA TCNDPGMPQN GTRYGDSREA GDTVTFQCDP
910 920 930 940 950
GYQLQGQAKI TCVQLNNRFF WQPDPPTCIA ACGGNLTGPA GVILSPNYPQ
960 970 980 990 1000
PYPPGKECDW RVKVNPDFVI ALIFKSFNME PSYDFLHIYE GEDSNSPLIG
1010 1020 1030 1040 1050
SYQGSQAPER IESSGNSLFL AFRSDASVGL SGFAIEFKEK PREACFDPGN
1060 1070 1080 1090 1100
IMNGTRVGTD FKLGSTITYQ CDSGYKILDP SSITCVIGAD GKPSWDQVLP
1110 1120 1130 1140 1150
SCNAPCGGQY TGSEGVVLSP NYPHNYTAGQ ICLYSITVPK EFVVFGQFAY
1160 1170 1180 1190 1200
FQTALNDLAE LFDGTHAQAR LLSSLSGSHS GETLPLATSN QILLRFSAKS
1210 1220 1230 1240 1250
GASARGFHFV YQAVPRTSDT QCSSVPEPRY GRRIGSEFSA GSIVRFECNP
1260 1270 1280 1290 1300
GYLLQGSTAL HCQSVPNALA QWNDTIPSCV VPCSGNFTQR RGTILSPGYP
1310 1320 1330 1340 1350
EPYGNNLNCI WKIIVTEGSG IQIQVISFAT EQNWDSLEIH DGGDVTAPRL
1360 1370 1380 1390 1400
GSFSGTTVPA LLNSTSNQLY LHFQSDISVA AAGFHLEYKT VGLAACQEPA
1410 1420 1430 1440 1450
LPSNSIKIGD RYMVNDVLSF QCEPGYTLQG RSHISCMPGT VRRWNYPSPL
1460 1470 1480 1490 1500
CIATCGGTLS TLGGVILSPG FPGSYPNNLD CTWRISLPIG YGAHIQFLNF
1510 1520 1530 1540 1550
STEANHDFLE IQNGPYHTSP MIGQFSGTDL PAALLSTTHE TLIHFYSDHS
1560 1570 1580 1590 1600
QNRQGFKLAY QAYELQNCPD PPPFQNGYMI NSDYSVGQSV SFECYPGYIL
1610 1620 1630 1640 1650
IGHPVLTCQH GINRNWNYPF PRCDAPCGYN VTSQNGTIYS PGFPDEYPIL
1660 1670 1680 1690 1700
KDCIWLITVP PGHGVYINFT LLQTEAVNDY IAVWDGPDQN SPQLGVFSGN
1710 1720 1730 1740 1750
TALETAYSST NQVLLKFHSD FSNGGFFVLN FHAFQLKKCQ PPPAVPQAEM
1760 1770 1780 1790 1800
LTEDDDFEIG DFVKYQCHPG YTLVGTDILT CKLSSQLQFE GSLPTCEGSS
1810 1820 1830 1840 1850
GQSPLLVVLS GNHTEQSNFT SRSNQLYLRW STDHATSKKG FKIRYAAPYC
1860 1870 1880 1890 1900
SLTHPLKNGG ILNRTAGAVG SKVHYFCKPG YRMVGHSNAT CRRNPLGMYQ
1910 1920 1930 1940 1950
WDSLTPLCQA VSCGIPESPG NGSFTGNEFT LDSKVVYECH EGFKLESSQQ
1960 1970 1980 1990 2000
ATAVCQEDGL WSNKGKPPTC KPVACPSIEA QLSEHVIWRL VSGSLNEYGA
2010 2020 2030 2040 2050
QVLLSCSPGY YLEGWRLLRC QANGTWNIGD ERPSCRVISC GSLSFPPNGN
2060 2070 2080 2090 2100
KIGTLTVYGA TAIFTCNTGY TLVGSHVREC LANGLWSGSE TRCLAGHCGS
2110 2120 2130 2140 2150
PDPIVNGHIS GDGFSYRDTV VYQCNPGFRL VGTSVRICLQ DHKWSGQTPV
2160 2170 2180 2190 2200
CVPITCGHPG NPAHGFTNGS EFNLNDVVNF TCNTGYLLQG VSRAQCRSNG
2210 2220 2230 2240 2250
QWSSPLPTCR VVNCSDPGFV ENAIRHGQQN FPESFEYGMS ILYHCKKGFY
2260 2270 2280 2290 2300
LLGSSALTCM ANGLWDRSLP KCLAISCGHP GVPANAVLTG ELFTYGAVVH
2310 2320 2330 2340 2350
YSCRGSESLI GNDTRVCQED SHWSGALPHC TGNNPGFCGD PGTPAHGSRL
2360 2370 2380 2390 2400
GDDFKTKSLL RFSCEMGHQL RGSPERTCLL NGSWSGLQPV CEAVSCGNPG
2410 2420 2430 2440 2450
TPTNGMIVSS DGILFSSSVI YACWEGYKTS GLMTRHCTAN GTWTGTAPDC
2460 2470 2480 2490 2500
TIISCGDPGT LANGIQFGTD FTFNKTVSYQ CNPGYVMEAV TSATIRCTKD
2510 2520 2530 2540 2550
GRWNPSKPVC KAVLCPQPPP VQNGTVEGSD FRWGSSISYS CMDGYQLSHS
2560 2570 2580 2590 2600
AILSCEGRGV WKGEIPQCLP VFCGDPGIPA EGRLSGKSFT YKSEVFFQCK
2610 2620 2630 2640 2650
SPFILVGSSR RVCQADGTWS GIQPTCIDPA HNTCPDPGTP HFGIQNSSRG
2660 2670 2680 2690 2700
YEVGSTVFFR CRKGYHIQGS TTRTCLANLT WSGIQTECIP HACRQPETPA
2710 2720 2730 2740 2750
HADVRAIDLP TFGYTLVYTC HPGFFLAGGS EHRTCKADMK WTGKSPVCKI
2760 2770 2780 2790 2800
PSDVFFVNSL WKGYYEYLGK RQPATLTVDW FNATSSKVNA TFSEASPVEL
2810 2820 2830 2840 2850
KLTGIYKKEE AHLLLKAFQI KGQADIFVSK FENDNWGLDG YVSSGLERGG
2860 2870 2880 2890 2900
FTFQGDIHGK DFGKFKLERQ DPLNPDQDSS SHYHGTSSGS VAAAILVPFF
2910 2920 2930 2940 2950
ALILSGFAFY LYKHRTRPKV QYNGYAGHEN SNGQASFENP MYDTNLKPTE
2960
AKAVRFDTTL NTVCTVV
Length:2,967
Mass (Da):323,574
Last modified:April 18, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBC2011645BC56D52
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96PZ7CSMD1_HUMAN
CUB and sushi domain-containing pro...
CSMD1 KIAA1890, UNQ5952/PRO19863
3,564Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W9C3F8W9C3_HUMAN
CUB and sushi domain-containing pro...
CSMD1
3,388Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIG2E5RIG2_HUMAN
CUB and sushi domain-containing pro...
CSMD1
3,565Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5GZ18F5GZ18_HUMAN
CUB and sushi domain-containing pro...
CSMD1
3,426Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC021523 Genomic DNA No translation available.
AC023296 Genomic DNA No translation available.
AC026991 Genomic DNA No translation available.
AC087692 Genomic DNA No translation available.
AC135324 Genomic DNA No translation available.
KF458665 Genomic DNA No translation available.
KF458666 Genomic DNA No translation available.
KF458667 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000335551; ENSP00000334828; ENSG00000183117

UCSC genome browser

More...
UCSCi
uc011kwj.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021523 Genomic DNA No translation available.
AC023296 Genomic DNA No translation available.
AC026991 Genomic DNA No translation available.
AC087692 Genomic DNA No translation available.
AC135324 Genomic DNA No translation available.
KF458665 Genomic DNA No translation available.
KF458666 Genomic DNA No translation available.
KF458667 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

Proteomic databases

PeptideAtlasiH7BXU2
PRIDEiH7BXU2
ProteomicsDBi43397

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
52810, 77 antibodies

Genome annotation databases

EnsembliENST00000335551; ENSP00000334828; ENSG00000183117
UCSCiuc011kwj.3, human

Organism-specific databases

EuPathDBiHostDB:ENSG00000183117.18
HGNCiHGNC:14026, CSMD1
OpenTargetsiENSG00000183117

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

GeneTreeiENSGT00940000155701

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
CSMD1, human

Gene expression databases

BgeeiENSG00000183117, Expressed in primary visual cortex and 156 other tissues
ExpressionAtlasiH7BXU2, baseline and differential

Family and domain databases

CDDicd00033, CCP, 26 hits
cd00041, CUB, 10 hits
Gene3Di2.60.120.290, 11 hits
InterProiView protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00431, CUB, 10 hits
PF00084, Sushi, 26 hits
SMARTiView protein in SMART
SM00032, CCP, 26 hits
SM00042, CUB, 10 hits
SUPFAMiSSF49854, SSF49854, 11 hits
SSF57535, SSF57535, 26 hits
PROSITEiView protein in PROSITE
PS01180, CUB, 10 hits
PS50923, SUSHI, 26 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH7BXU2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H7BXU2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: October 7, 2020
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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