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Protein
Submitted name:

Heterogeneous nuclear ribonucleoprotein L-like

Gene

HNRNPLL

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Heterogeneous nuclear ribonucleoprotein L-likeImported
Gene namesi
Name:HNRNPLLImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000143889.15
HGNCiHGNC:25127 HNRNPLL

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143889

PTM / Processingi

Proteomic databases

MaxQBiH7BXH8
PeptideAtlasiH7BXH8
PRIDEiH7BXH8

Expressioni

Gene expression databases

BgeeiENSG00000143889 Expressed in 201 organ(s), highest expression level in intestine
ExpressionAtlasiH7BXH8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH7BXH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 85RRMInterPro annotationAdd BLAST75

Phylogenomic databases

eggNOGiKOG1456 Eukaryota
ENOG410XQHN LUCA
GeneTreeiENSGT00550000074508

Family and domain databases

CDDicd12781 RRM1_hnRPLL, 1 hit
cd12786 RRM2_hnRPLL, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR006536 HnRNP-L/PTB
IPR034985 hnRPLL_RRM1
IPR034986 hnRPLL_RRM2
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
TIGRFAMsiTIGR01649 hnRNP-L_PTB, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H7BXH8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGSHHKVSVS PVVHVRGLCE SVVEADLVEA LEKFGTICYV MMMPFKRQAL
60 70 80 90 100
VEFENIDSAK ECVTFAADEP VYIAGQQAFF NYSTSKRITR PGNTDDPSGG
110 120 130 140 150
NKVLLLSIQN PLYPITVDVL YTVCNPVGKV QRIVIFKRNG IQAMVEFESV
160 170 180 190 200
LCAQKAKAAL NGADIYAGCC TLKIEYARPT RLNVIRNDND SWDYTKPYLG
210
RRGCCWLMLK LLERSPL
Length:217
Mass (Da):24,228
Last modified:April 18, 2012 - v1
Checksum:iED070725CF1D7EF9
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8WVV9HNRLL_HUMAN
Heterogeneous nuclear ribonucleopro...
HNRNPLL HNRPLL, SRRF, BLOCK24
542Annotation score:
C9IYN3C9IYN3_HUMAN
Heterogeneous nuclear ribonucleopro...
HNRNPLL HNRPLL, hCG_15881
537Annotation score:
D6W592D6W592_HUMAN
Heterogeneous nuclear ribonucleopro...
HNRNPLL HNRPLL, hCG_15881
542Annotation score:
B7WPG3B7WPG3_HUMAN
Heterogeneous nuclear ribonucleopro...
HNRNPLL
508Annotation score:
C9JJZ7C9JJZ7_HUMAN
Heterogeneous nuclear ribonucleopro...
HNRNPLL
149Annotation score:
H7C464H7C464_HUMAN
Heterogeneous nuclear ribonucleopro...
HNRNPLL
133Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011247 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000272249; ENSP00000272249; ENSG00000143889
UCSCiuc061iil.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011247 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH7BXH8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH7BXH8
PeptideAtlasiH7BXH8
PRIDEiH7BXH8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000272249; ENSP00000272249; ENSG00000143889
UCSCiuc061iil.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000143889.15
HGNCiHGNC:25127 HNRNPLL
OpenTargetsiENSG00000143889
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1456 Eukaryota
ENOG410XQHN LUCA
GeneTreeiENSGT00550000074508

Miscellaneous databases

ChiTaRSiHNRNPLL human

Gene expression databases

BgeeiENSG00000143889 Expressed in 201 organ(s), highest expression level in intestine
ExpressionAtlasiH7BXH8 baseline and differential

Family and domain databases

CDDicd12781 RRM1_hnRPLL, 1 hit
cd12786 RRM2_hnRPLL, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR006536 HnRNP-L/PTB
IPR034985 hnRPLL_RRM1
IPR034986 hnRPLL_RRM2
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
TIGRFAMsiTIGR01649 hnRNP-L_PTB, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH7BXH8_HUMAN
AccessioniPrimary (citable) accession number: H7BXH8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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