UniProtKB - H6UYS0 (H6UYS0_HUMAN)
Protein
Alpha-synuclein
Gene
SNCA
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Alpha-synucleinUniRule annotationARBA annotation |
Gene namesi | Name:SNCAImported ORF Names:hCG_1777783Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000145335.15 |
Subcellular locationi
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
Keywords - Cellular componenti
Cell junction, MembraneARBA annotation, NucleusARBA annotation, SecretedARBA annotation, SynapseARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000145335, Expressed in bone marrow and 250 other tissues |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 86 – 126 | DisorderedSequence analysisAdd BLAST | 41 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 102 – 126 | AcidicSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Family and domain databases
InterProi | View protein in InterPro IPR001058, Synuclein IPR002460, Synuclein_alpha |
PANTHERi | PTHR13820, PTHR13820, 1 hit PTHR13820:SF5, PTHR13820:SF5, 1 hit |
Pfami | View protein in Pfam PF01387, Synuclein, 1 hit |
PRINTSi | PR01212, ASYNUCLEIN PR01211, SYNUCLEIN |
i Sequence
Sequence statusi: Complete.
H6UYS0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV VAEKTKEQVT
60 70 80 90 100
NVGGAVVTGV TAVAQKTVEG AGSIAAATGF VKKDQLGKNE EGAPQEGILE
110 120
DMPVDPDNEA YEMPSEEGYQ DYEPEA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JN709859 mRNA Translation: AFA25669.1 JN709862 mRNA Translation: AFA25672.1 JN709865 mRNA Translation: AFA25675.1 JN709868 mRNA Translation: AFA25678.1 CH471057 Genomic DNA Translation: EAX06035.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JN709859 mRNA Translation: AFA25669.1 JN709862 mRNA Translation: AFA25672.1 JN709865 mRNA Translation: AFA25675.1 JN709868 mRNA Translation: AFA25678.1 CH471057 Genomic DNA Translation: EAX06035.1 |
3D structure databases
SMRi | H6UYS0 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 14688, 2979 antibodies |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000145335.15 |
Miscellaneous databases
ChiTaRSi | SNCA, human |
Gene expression databases
Bgeei | ENSG00000145335, Expressed in bone marrow and 250 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR001058, Synuclein IPR002460, Synuclein_alpha |
PANTHERi | PTHR13820, PTHR13820, 1 hit PTHR13820:SF5, PTHR13820:SF5, 1 hit |
Pfami | View protein in Pfam PF01387, Synuclein, 1 hit |
PRINTSi | PR01212, ASYNUCLEIN PR01211, SYNUCLEIN |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H6UYS0_HUMAN | |
Accessioni | H6UYS0Primary (citable) accession number: H6UYS0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | December 2, 2020 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |