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Protein

Alpha-synuclein

Gene

SNCA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-synucleinUniRule annotation
Gene namesi
Name:SNCAImported
ORF Names:hCG_1777783Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000145335.15

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSG00000145335 Expressed in 237 organ(s), highest expression level in bone marrow
ExpressionAtlasiH6UYS0 baseline and differential

Structurei

3D structure databases

SMRiH6UYS0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the synuclein family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR001058 Synuclein
IPR002460 Synuclein_alpha
PANTHERiPTHR13820 PTHR13820, 1 hit
PTHR13820:SF5 PTHR13820:SF5, 1 hit
PfamiView protein in Pfam
PF01387 Synuclein, 1 hit
PRINTSiPR01212 ASYNUCLEIN
PR01211 SYNUCLEIN

Sequencei

Sequence statusi: Complete.

H6UYS0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV VAEKTKEQVT
60 70 80 90 100
NVGGAVVTGV TAVAQKTVEG AGSIAAATGF VKKDQLGKNE EGAPQEGILE
110 120
DMPVDPDNEA YEMPSEEGYQ DYEPEA
Length:126
Mass (Da):13,109
Last modified:April 18, 2012 - v1
Checksum:i0F87D9A60E831E02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN709859 mRNA Translation: AFA25669.1
JN709862 mRNA Translation: AFA25672.1
JN709865 mRNA Translation: AFA25675.1
JN709868 mRNA Translation: AFA25678.1
CH471057 Genomic DNA Translation: EAX06035.1
UniGeneiHs.21374

Similar proteinsi

Entry informationi

Entry nameiH6UYS0_HUMAN
AccessioniPrimary (citable) accession number: H6UYS0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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