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Entry version 41 (07 Apr 2021)
Sequence version 1 (18 Apr 2012)
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Protein

Calmodulin

Gene
N/A
Organism
Phytophthora ramorum (Sudden oak death agent)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi305 – 316PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi341 – 352PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CalmodulinARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhytophthora ramorum (Sudden oak death agent)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri164328 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarStramenopilesOomycotaPeronosporalesPeronosporaceaePhytophthora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005238 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
164328.Phyra80594

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini292 – 327EF-handInterPro annotationAdd BLAST36
Domaini328 – 363EF-handInterPro annotationAdd BLAST36
Domaini1358 – 1386WWInterPro annotationAdd BLAST29
Domaini1548 – 1575WWInterPro annotationAdd BLAST28

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 42DisorderedSequence analysisAdd BLAST42
Regioni91 – 128DisorderedSequence analysisAdd BLAST38
Regioni1520 – 1550DisorderedSequence analysisAdd BLAST31

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili891 – 911Sequence analysisAdd BLAST21
Coiled coili1028 – 1055Sequence analysisAdd BLAST28
Coiled coili1060 – 1098Sequence analysisAdd BLAST39
Coiled coili1120 – 1140Sequence analysisAdd BLAST21
Coiled coili1166 – 1186Sequence analysisAdd BLAST21
Coiled coili1212 – 1232Sequence analysisAdd BLAST21
Coiled coili1244 – 1268Sequence analysisAdd BLAST25
Coiled coili1303 – 1352Sequence analysisAdd BLAST50

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi91 – 110PolarSequence analysisAdd BLAST20
Compositional biasi1520 – 1543PolarSequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0027, Eukaryota
KOG0160, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_245070_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H3GTU7

Identification of Orthologs from Complete Genome Data

More...
OMAi
EYWDENA

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00051, EFh, 1 hit
cd00201, WW, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR000048, IQ_motif_EF-hand-BS
IPR001202, WW_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13499, EF-hand_7, 1 hit
PF00612, IQ, 8 hits
PF00397, WW, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00054, EFh, 2 hits
SM00015, IQ, 16 hits
SM00456, WW, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473, SSF47473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018, EF_HAND_1, 2 hits
PS50222, EF_HAND_2, 2 hits
PS50096, IQ, 13 hits
PS50020, WW_DOMAIN_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H3GTU7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNNNHEDDR RFSRLLSSPT PLPPAAPAKT QALLRRRRRV PPRDVQQHEP
60 70 80 90 100
WLFQSTNVRP LPVMPLASPS LSLSTSDTSF FYLDLNSLKS LLPPSDTRSR
110 120 130 140 150
PRSSEDAYGS TVRFRNARGP SSRGRQAPPA RLEALNLSTT QAMDKKHRHT
160 170 180 190 200
KRRRQVGLVS KHKLRRKALR LDSAKVRPSS QEMLDADAAA VYLSPSKHGS
210 220 230 240 250
SKARKNVTLQ HVGEHRPGMR RRPAMHYAFD YDSDGQGRTE RPVTPLEDLD
260 270 280 290 300
EEQRQKTIIA THLNLTLEEY ERLDAAFGNG SQPSGASEDD HSMTERYREE
310 320 330 340 350
FHAFDVDNSG SISPDELRQL LLASGEEMDD AELASVIQQA DTDHDGEINF
360 370 380 390 400
DEFIDLMRAR KRLLQVANQM GVNGNGPPTV SSTISPGLAR NVGASGQMLP
410 420 430 440 450
PLKLAARQAK RHLQPQSRSL AGTRATPSCL RPGSKVDIGD LRRELALSEY
460 470 480 490 500
GMQELNSKVR EGLQWVQQHC PVRSLKAQVF CHRWGMEKVH QLFVRLQSQQ
510 520 530 540 550
ISRAFRKWSA FLMFERNKIK ANLFLKCKAS QKMTAIMTKW RRKVTRRKFV
560 570 580 590 600
RWKTECVLDA RNELHSAAIE IQRIVRGDLA RLRRLRIQEE VAVIHLQALV
610 620 630 640 650
RGRMARTVAS RKRRAKLEHE AASLLQRCYR GYTGKRLSRA LFKAQRETLA
660 670 680 690 700
ACRIQRTFRT FQRRELLRVI QLTKLENDSA VVIQCNVRRY LARKERKRRA
710 720 730 740 750
RCQLRERSAA VLQRCTRGYL ARCRVLTLRQ QIHAALIIQC FSRVCRSRRR
760 770 780 790 800
VHMLRTEKQS KERHAFERKA ATRIQARWRC TSTRKRYLLD KQRRAETLKL
810 820 830 840 850
ERFRRLTSAV VIQSLFRGYL ARRRAQRARY ERLKWMNFTL LNSSALKIQA
860 870 880 890 900
FWRGFHGRLA SHLRLQAQKA QQHQENEAAK RIQVIARGKL AREERRKLDQ
910 920 930 940 950
ERAKLASQQR TRVKAALRIQ KVFRGKQARK MVREFQHKHR EEARLALERL
960 970 980 990 1000
VHQTKTRAAT KIQSCARRFL ARCQYLHCKH EMELRTQQEE LRITKNHAAV
1010 1020 1030 1040 1050
VIQCAMRRAG AKRILLQRRR EFEKRISMMA SEKAHDEIER LRQEQEEELL
1060 1070 1080 1090 1100
KLKLQLMFQA STANEEAAKL RDELAQQREE EEERRREEAQ ELARLRLETL
1110 1120 1130 1140 1150
MQQHEIDTRI EQDHRKKLEA QQLREKLAME KQAQHEKEAA MRTQENEELA
1160 1170 1180 1190 1200
ALKMATMLST KPTSKQEEQD TEARTLQQEV AHLKQAALAI HKDQARLKIQ
1210 1220 1230 1240 1250
AVCLKHIARK RLAKLQQQLA AMDDIHDEEQ RVRLKAEHQK ALALARLKAM
1260 1270 1280 1290 1300
MDDEARAREQ EIKELEVEML ERAGKEKERI ALRNASARKI QSQARGYLAR
1310 1320 1330 1340 1350
QRVKAIQRKI DKEREDRAKA MQETIEAAEA EVAEALIEAG ETEANAAEAS
1360 1370 1380 1390 1400
EELNADEWVE YWDENAQASY FYNIRTQEAS WTRPVSTPSA KAMEIVMTAT
1410 1420 1430 1440 1450
GLTDEREQEP GAGYIDYAVA EQVDANGYPV PASTAESYAD EYGYYDQYGQ
1460 1470 1480 1490 1500
YHYYEQSNAA YYGTQAFGQG YPQVMGVQPN YAAAAAANYA YQAAAAMAFN
1510 1520 1530 1540 1550
QAMMYGAPMM GYGNPATAQP VQQYPQPSEA VATASTSESE SSGDAVPPDP
1560 1570
WEKFFDQYTG AAYYYNNITG EQYWA
Length:1,575
Mass (Da):181,723
Last modified:April 18, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD53E8D0FD3B96446
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DS566047 Genomic DNA No translation available.

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
Phyra80594; Phyra80594; Phyra80594

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS566047 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi164328.Phyra80594

Genome annotation databases

EnsemblProtistsiPhyra80594; Phyra80594; Phyra80594

Phylogenomic databases

eggNOGiKOG0027, Eukaryota
KOG0160, Eukaryota
HOGENOMiCLU_245070_0_0_1
InParanoidiH3GTU7
OMAiEYWDENA

Family and domain databases

CDDicd00051, EFh, 1 hit
cd00201, WW, 2 hits
InterProiView protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR000048, IQ_motif_EF-hand-BS
IPR001202, WW_dom
PfamiView protein in Pfam
PF13499, EF-hand_7, 1 hit
PF00612, IQ, 8 hits
PF00397, WW, 1 hit
SMARTiView protein in SMART
SM00054, EFh, 2 hits
SM00015, IQ, 16 hits
SM00456, WW, 2 hits
SUPFAMiSSF47473, SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018, EF_HAND_1, 2 hits
PS50222, EF_HAND_2, 2 hits
PS50096, IQ, 13 hits
PS50020, WW_DOMAIN_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH3GTU7_PHYRM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H3GTU7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: April 7, 2021
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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