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Entry version 33 (31 Jul 2019)
Sequence version 1 (18 Apr 2012)
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Protein
Submitted name:

Castor zinc finger 1

Gene
N/A
Organism
Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Castor zinc finger 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri99883 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTetraodon
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007303 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini566 – 595C2H2-typeInterPro annotationAdd BLAST30
Domaini1478 – 1502C2H2-typeInterPro annotationAdd BLAST25

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni26 – 166DisorderedSequence analysisAdd BLAST141
Regioni283 – 304DisorderedSequence analysisAdd BLAST22
Regioni938 – 973DisorderedSequence analysisAdd BLAST36
Regioni1092 – 1112DisorderedSequence analysisAdd BLAST21
Regioni1383 – 1413DisorderedSequence analysisAdd BLAST31
Regioni1610 – 1631DisorderedSequence analysisAdd BLAST22
Regioni1667 – 1739DisorderedSequence analysisAdd BLAST73

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi26 – 45PolarSequence analysisAdd BLAST20
Compositional biasi65 – 81PolyampholyteSequence analysisAdd BLAST17
Compositional biasi139 – 154PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1610 – 1624PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1714 – 1739PolyampholyteSequence analysisAdd BLAST26

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4377 Eukaryota
ENOG410XRBA LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008187

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H3DCI7

Identification of Orthologs from Complete Genome Data

More...
OMAi
FLHKVHF

TreeFam database of animal gene trees

More...
TreeFami
TF324787

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040373 CASZ1
IPR013087 Znf_C2H2_type

The PANTHER Classification System

More...
PANTHERi
PTHR12451 PTHR12451, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 7 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H3DCI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
KSKMAAKRKG GLKLNAICAK LSRQVVFDSS SQNAEGDQSV ADNSERGSSH
60 70 80 90 100
YDDSETNFPE SLTQSLEEDQ RRREAIEKWV NGEYSDEPPA PDDEQESEFK
110 120 130 140 150
ASTDEDVPPE GVYMVQPKGC SDDEEEEARS VTVSQDGSFH DNKDTDDKTS
160 170 180 190 200
KDDGYIGTRQ SAGEASALRD YAANTMNEFL GMFGYDDQQV RDELTKKISF
210 220 230 240 250
EKLKAATSDP SSLSSEETSR RARFSKYEEY IRKLKAGEAL PWPMHASPPK
260 270 280 290 300
PEDLNSKLTQ DTSATMIQTS GCLPGAEAQI YPSSLEHKSP GGPQLGASQS
310 320 330 340 350
PNSSHIQNMV SRASKYDFYI QKLKMGESLQ QQNGNSYKRT SKYDLENVKF
360 370 380 390 400
LHLFKPGEGN PDMGGAIAFK TGKVGRPSKY DIRTIQKLMP GNSEASMMPN
410 420 430 440 450
VLATAPGNPG APGVPAVAGS GASITPGLTM DQTGNISFNT SDYLKSSFSK
460 470 480 490 500
TDSITTGTVS SVKNGLPPDK PAPDDINLYQ KYIARFSGSQ HCGHVHCAYQ
510 520 530 540 550
YREHYHCMDP DCNYQRFTSK QDVIRHYNMH KKRDNSLQHG FMRFSPLDDC
560 570 580 590 600
SVYYHGCHLN GKSTHYHCMQ VGCSKVYTST SDVMTHENFH KKNAQLINDG
610 620 630 640 650
FQRFRATEDC GTVGCQFYGQ KTTHFHCRRP GCTFTFKNKC DIEKHKSYHI
660 670 680 690 700
KDDAYAKDGF KKFYKYEECK YEGCVYSKAT NHFHCIRSGC FTFTSTSQMT
710 720 730 740 750
SHKRKHERRH IRSSGVMGFS STFLAKDEPE ESSNDDLVDF STISSKNSSL
760 770 780 790 800
SASPTTQQST TVPHLLATPT TAVSCSSSTS VHTPKPAPTL SIAGQRMSSL
810 820 830 840 850
LSQALPSNVP VALALSNSAL ATSNPFFPMM PRLPLQPPPP AATLISAVSS
860 870 880 890 900
GAHSMPTDSL TQGCSTAGAD GIIASTPTSF PTSSIMEKIS ASKGLISPMM
910 920 930 940 950
ARLAAAALKP SSSAEIGNGQ PASASQFNLV QVKQEPADCN PVAPQDSAQE
960 970 980 990 1000
HSLDLSKKDH SNESNGHPVP GNTSLLSSLM NKMTQVNPAL YSTMNLKTEL
1010 1020 1030 1040 1050
EAGQGANACE GAQYLGRVLK KPALEKPTEI WRTYLRRFDT DDFCEAQCDF
1060 1070 1080 1090 1100
LQKVHFHCLV EDCGALFSTV DGAIKHANFH LRATLKVKSD TQFGETKESG
1110 1120 1130 1140 1150
EGAPLQPAAP VSAANNPSMD VAHLTASGGY SSPPPSLLAW KQLTGSIPQM
1160 1170 1180 1190 1200
PASMPNSTLA TTSLENAKPQ VKPGFLQFQE NDPCLATDCK YSNKFHFHCL
1210 1220 1230 1240 1250
FGNCKYVCKT SGKAESHCLD HINPNNSLVN IRDQFSYYSL QCLCPNQHCE
1260 1270 1280 1290 1300
FRMRGHYHCL RPGCYFVTNI TTKLPWHVKK HEKAERRAAN GFRYFTKREE
1310 1320 1330 1340 1350
CGRLGCKYNQ VNSHFHCIRE GCHFSFLLKH QMTSHARKHM RRMLGKNFDR
1360 1370 1380 1390 1400
VPSQSGVNSN FSSAFMDETD DYMDYMGGGG SPLGLSSESS NQDRSCTSTP
1410 1420 1430 1440 1450
VGNDGSPAGN TISIPTATGS KKRFWIIEDM SPFGKRRKTA SSRKMLDEGM
1460 1470 1480 1490 1500
MLDGFRRYDL YENCKDSSCQ FSLKVTHYHC TRENCGYKFC GRTHMYKHAQ
1510 1520 1530 1540 1550
HHDRVDNLVL DDFKRFKSTL SCNFPDCQFS GNSTHFHCLR CGFRCTDSTK
1560 1570 1580 1590 1600
VTAHRKHHGK QDVISAAGFC QFSSSVDCEV LDCKYKLKCS HFHCTFPECK
1610 1620 1630 1640 1650
HTVVGMSQMD SHKRKHEKQE RGSITADYSH PYPPSSLSLD SSLNLSTDTS
1660 1670 1680 1690 1700
SSLFFLKNAA GLGLSDSLDL SKKMPQDAGR PRHNPAPPLA LHAAQDDNTG
1710 1720 1730
TSGEAEDDLS PEDEAHATDS NDDSTAEADG EKDNGDGFD
Length:1,739
Mass (Da):191,811
Last modified:April 18, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC29E86A2578863D5
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSTNIT00000018455; ENSTNIP00000018230; ENSTNIG00000015174

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTNIT00000018455; ENSTNIP00000018230; ENSTNIG00000015174

Phylogenomic databases

eggNOGiKOG4377 Eukaryota
ENOG410XRBA LUCA
GeneTreeiENSGT00390000008187
InParanoidiH3DCI7
OMAiFLHKVHF
TreeFamiTF324787

Family and domain databases

InterProiView protein in InterPro
IPR040373 CASZ1
IPR013087 Znf_C2H2_type
PANTHERiPTHR12451 PTHR12451, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 11 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 7 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH3DCI7_TETNG
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H3DCI7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: July 31, 2019
This is version 33 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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