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Entry version 38 (02 Dec 2020)
Sequence version 1 (18 Apr 2012)
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Protein
Submitted name:

Zinc finger, BED-type containing 4

Gene
N/A
Organism
Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Zinc finger, BED-type containing 4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri99883 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTetraodon
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007303 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 94BED-typeInterPro annotationAdd BLAST58
Domaini204 – 261BED-typeInterPro annotationAdd BLAST58
Domaini377 – 433BED-typeInterPro annotationAdd BLAST57
Domaini477 – 534BED-typeInterPro annotationAdd BLAST58

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni118 – 166DisorderedSequence analysisAdd BLAST49
Regioni182 – 206DisorderedSequence analysisAdd BLAST25
Regioni455 – 476DisorderedSequence analysisAdd BLAST22
Regioni960 – 983DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi118 – 149PolarSequence analysisAdd BLAST32
Compositional biasi150 – 164PolyampholyteSequence analysisAdd BLAST15

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161365

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006260_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H3CMT1

Identification of Orthologs from Complete Genome Data

More...
OMAi
VCRYCSC

TreeFam database of animal gene trees

More...
TreeFami
TF322818

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008906, HATC_C_dom
IPR012337, RNaseH-like_sf
IPR003656, Znf_BED
IPR036236, Znf_C2H2_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05699, Dimer_Tnp_hAT, 1 hit
PF02892, zf-BED, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098, SSF53098, 1 hit
SSF57667, SSF57667, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50808, ZF_BED, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H3CMT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DDYSNLLSGY TSTLYDVAMD AVTQSLLSSM RSNANPRKKS PAWNHFCISP
60 70 80 90 100
RDSTKAICLY CMKEFSRGKN EKDLSTSCLM RHVRRAHPTV LLQDGADISP
110 120 130 140 150
SHLMSSFASS LIPPIPNSPK NGDLTNSLLS TASKSTSPST SSAENSDLSS
160 170 180 190 200
KDAPKAEPNQ DPHHKTDALG TILVSSHSSE SYAEDLLDGA SERPPGTPKS
210 220 230 240 250
SSSRRRSAVW KHFYLSPVDS SKAVCIHCMN EFSRGKNGKD LGTSCLIRHM
260 270 280 290 300
WRAHKDVVIE ENGHGNHIPP PYTNPPSLLS RTKMHEPLDI KKESPILPSS
310 320 330 340 350
PETLTDEFPQ NIEESMNIKV EPDELMHLSG QESSLSLSFK TPGEDTPVAS
360 370 380 390 400
SPCDLPEGPG LQQDHLVFQQ NKKIMKRVKS EVWHHFIVSP VDQLKALCRY
410 420 430 440 450
CPCVISRGKR GDFGTSCLMR HLMRRHPDVL KNQKSTDEKD SSPLPYNNLA
460 470 480 490 500
AADAVSAKET ENAASEKKPQ TPPVFSKKTS KLWNHFSISP ADPTKVVCLH
510 520 530 540 550
CSRTISRGKK TTNLGTSCLF RHLQRFHGHA LESNNAISGD VPSAEIHVKQ
560 570 580 590 600
ELMETSVYGT EQTCERFDDH HPVAKKITRL LAEMLALDLQ PSAMVENAGL
610 620 630 640 650
SRLLEYLQPQ YSLPPSSYFT STAIPDMYER VKDAVLTHLK EAEGGVVHFT
660 670 680 690 700
TSIWVSSQTR EYLTLSAHWA TYESSLRPQG QDFHCSALLS VSQIDCDHDM
710 720 730 740 750
QDIPKQLEYL WDSWITSSGL KKGFTVSDNA AIRHTLEDHG HVTMHCFGHT
760 770 780 790 800
LDLIISEAIK SQRMVQNLLS IARKICERVH RSAKAKEKLA ELQRAHQLPE
810 820 830 840 850
NQLIQDVPSK WRTSFSMLER LVEQKSAIDE LSIECNFREI ISCDQWEVML
860 870 880 890 900
SVCTALKPFE VAYREMSNRT ATLGQVIPLI HILNRKIDLL FDETVGIDNM
910 920 930 940 950
LRSLKEAMVS RLSATLQDPR YTWATMLDPR YKTSLFTEED AEQCKQDLIQ
960 970 980 990 1000
EIDLSSSTSL AAKSPLPNGC GESPPSSHSN KDNLWSLMDD LRQKIQDEEK
1010 1020 1030 1040 1050
PKSPELAVLE YLEEDILDQS CDPLDYWNLK KFLWPDLAKV AARYLGCPPS
1060 1070 1080 1090
IVPAETLFST ASVNCSLNQP RPVLDNVEGL LFLKVNLPLI YFQY
Length:1,094
Mass (Da):122,558
Last modified:April 18, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5E0FF711155C8F96
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSTNIT00000009737; ENSTNIP00000009562; ENSTNIG00000006775

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSTNIT00000009737; ENSTNIP00000009562; ENSTNIG00000006775

Phylogenomic databases

GeneTreeiENSGT00940000161365
HOGENOMiCLU_006260_0_0_1
InParanoidiH3CMT1
OMAiVCRYCSC
TreeFamiTF322818

Family and domain databases

InterProiView protein in InterPro
IPR008906, HATC_C_dom
IPR012337, RNaseH-like_sf
IPR003656, Znf_BED
IPR036236, Znf_C2H2_sf
PfamiView protein in Pfam
PF05699, Dimer_Tnp_hAT, 1 hit
PF02892, zf-BED, 4 hits
SUPFAMiSSF53098, SSF53098, 1 hit
SSF57667, SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50808, ZF_BED, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH3CMT1_TETNG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H3CMT1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: December 2, 2020
This is version 38 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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