UniProtKB - H3BVG0 (H3BVG0_HUMAN)
Protein
Nuclear pore complex protein Nup93
Gene
NUP93
Organism
Homo sapiens (Human)
Status
Functioni
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.UniRule annotation
GO - Molecular functioni
- structural constituent of nuclear pore Source: InterPro
GO - Biological processi
- mRNA transport Source: UniProtKB-KW
- positive regulation of SMAD protein signal transduction Source: Ensembl
- protein transport Source: UniProtKB-KW
- SMAD protein signal transduction Source: Ensembl
Keywordsi
Biological process | mRNA transport, Protein transport, Translocation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Nuclear pore complex protein Nup93UniRule annotation |
Gene namesi | Name:NUP93Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:28958, NUP93 |
VEuPathDBi | HostDB:ENSG00000102900.12 |
Subcellular locationi
Nucleus
- Nucleus envelope ARBA annotation
- Nucleus membrane ARBA annotation; Peripheral membrane protein ARBA annotation
- nuclear pore complex UniRule annotation
Nucleus
- nuclear membrane Source: UniProtKB-SubCell
- nuclear pore Source: UniProtKB-SubCell
Keywords - Cellular componenti
MembraneUniRule annotation, Nuclear pore complexUniRule annotation, NucleusPTM / Processingi
Proteomic databases
EPDi | H3BVG0 |
MaxQBi | H3BVG0 |
PeptideAtlasi | H3BVG0 |
PRIDEi | H3BVG0 |
ProteomicsDBi | 43206 |
PTM databases
SwissPalmi | H3BVG0 |
Expressioni
Gene expression databases
Bgeei | ENSG00000102900, Expressed in left lobe of thyroid gland and 227 other tissues |
ExpressionAtlasi | H3BVG0, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00390000016353 |
OMAi | RHAHEQN |
Family and domain databases
InterProi | View protein in InterPro IPR007231, Nucleoporin_int_Nup93/Nic96 |
PANTHERi | PTHR11225, PTHR11225, 1 hit |
Pfami | View protein in Pfam PF04097, Nic96, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All
H3BVG0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDTEGFGELL QQAEQLAAET EGISELPHVE RNLQEIQQAG ERLRSRTLTR
60 70 80 90 100
TSQETADVKA SVLLGSRGLD ISHISQRLES LSAATTFEPL EPVKDTDIQG
110 120 130 140 150
FLKNEKDNAL LSAIEESRKR TFGMAEEYHR ESMLVEWEQV KQRILHTLLA
160 170 180 190 200
SGEDALDFTQ ESEPSYISDV GPPGRSSLDN IEMAYARQIY IYNEKIVNGH
210 220 230 240 250
LQPNLVDLCA SVAELDDKSI SDMWTMVKQM TDVLLTPATD ALKNRSSVEV
260 270 280 290 300
RMEFVRQALA YLEQSYKNYT LVTVFGNLHQ AQLGGVPGTY QLVRSFLNIK
310 320 330 340 350
LPAPLPGLQD GEVEGHPVWA LIYYCMRCGD LLAASQVVNR AQHQLGEFKT
360 370 380 390 400
WFQEYMNSKD RRLSPATENK LRLHYRRALR NNTDPYKRAV YCIIGRCDVT
410 420 430 440 450
DNQSEVADKT EDYLWLKLNQ VCFDDDGTSS PQDRLTLSQF QKQLLEDYGE
460 470 480 490 500
SHFTVNQQPF LYFQVLFLTA QFEAAVAFLF RMERLRCHAV HVALVLFELK
510 520 530 540 550
LLLKSSGQSA QLLSHEPGDP PCLRRLNFVR LLMLYTRKFE STDPREALQY
560 570 580 590 600
FYFLRDEKDS QGENMFLRCV SELVIESREF DMILGKLEND GSRKPGVIDK
610 620 630 640 650
FTSDTKPIIN KVASVAENKG LFEEAAKLYD LAKNADKVLE LMNKLLSPVV
660 670 680 690 700
PQISAPQSNK ERLKNMALSI AERYRAQGIS ANKFVDSTFY LLLDLITFFD
710 720 730 740 750
EYHSGHIDRA FDIIERLKLV PLNQESVEER VAAFRNFSDE IRHNLSEVLL
760 770 780 790 800
ATMNILFTQF KRLKGTSPSS SSRPQRVIED RDSGLALLPR LECNDTISAH
810 820 830 840 850
CNLYLLGSSH PPTSPSQVAG TTATPKSSPH SDYLCWNDTI PNVWGHQCEA
860 870 880
GADGGPHELS AMLCGSLGRH TVSTSGTWAH
Computationally mapped potential isoform sequencesi
There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8N1F7 | NUP93_HUMAN | Nuclear pore complex protein Nup93 | NUP93 KIAA0095 | 819 | Annotation score: | ||
H3BRD9 | H3BRD9_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 140 | Annotation score: | ||
H3BPA9 | H3BPA9_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 229 | Annotation score: | ||
H3BVE2 | H3BVE2_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 117 | Annotation score: | ||
H3BP95 | H3BP95_HUMAN | Nuclear pore complex protein Nup93 | NUP93 | 156 | Annotation score: | ||
H3BRI8 | H3BRI8_HUMAN | 93 kDa nucleoporin | NUP93 | 151 | Annotation score: | ||
H3BV15 | H3BV15_HUMAN | 93 kDa nucleoporin | NUP93 | 84 | Annotation score: | ||
H3BM93 | H3BM93_HUMAN | 93 kDa nucleoporin | NUP93 | 178 | Annotation score: | ||
H3BMX0 | H3BMX0_HUMAN | 93 kDa nucleoporin | NUP93 | 125 | Annotation score: | ||
H3BNN5 | H3BNN5_HUMAN | 93 kDa nucleoporin | NUP93 | 132 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012181 Genomic DNA No translation available. AC106779 Genomic DNA No translation available. AC127456 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000569842; ENSP00000458101; ENSG00000102900 |
UCSCi | uc059umz.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012181 Genomic DNA No translation available. AC106779 Genomic DNA No translation available. AC127456 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | H3BVG0, 1 interactor |
MINTi | H3BVG0 |
PTM databases
SwissPalmi | H3BVG0 |
Proteomic databases
EPDi | H3BVG0 |
MaxQBi | H3BVG0 |
PeptideAtlasi | H3BVG0 |
PRIDEi | H3BVG0 |
ProteomicsDBi | 43206 |
Protocols and materials databases
Antibodypediai | 14851, 121 antibodies |
Genome annotation databases
Ensembli | ENST00000569842; ENSP00000458101; ENSG00000102900 |
UCSCi | uc059umz.1, human |
Organism-specific databases
HGNCi | HGNC:28958, NUP93 |
OpenTargetsi | ENSG00000102900 |
VEuPathDBi | HostDB:ENSG00000102900.12 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000016353 |
OMAi | RHAHEQN |
Miscellaneous databases
ChiTaRSi | NUP93, human |
Gene expression databases
Bgeei | ENSG00000102900, Expressed in left lobe of thyroid gland and 227 other tissues |
ExpressionAtlasi | H3BVG0, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR007231, Nucleoporin_int_Nup93/Nic96 |
PANTHERi | PTHR11225, PTHR11225, 1 hit |
Pfami | View protein in Pfam PF04097, Nic96, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BVG0_HUMAN | |
Accessioni | H3BVG0Primary (citable) accession number: H3BVG0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | February 10, 2021 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |