UniProtKB - H3BU30 (H3BU30_HUMAN)
Protein
Submitted name:
Nuclear factor of-activated T-cells, cytoplasmic 3
Gene
NFATC3
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
- DNA-binding transcription factor activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Nuclear factor of-activated T-cells, cytoplasmic 3Imported |
Gene namesi | Name:NFATC3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000072736.18 |
HGNCi | HGNC:7777, NFATC3 |
PTM / Processingi
Proteomic databases
MaxQBi | H3BU30 |
PeptideAtlasi | H3BU30 |
PRIDEi | H3BU30 |
ProteomicsDBi | 42811 |
Expressioni
Gene expression databases
Bgeei | ENSG00000072736, Expressed in leukocyte and 227 other tissues |
ExpressionAtlasi | H3BU30, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 33 – 85 | RHDInterPro annotationAdd BLAST | 53 |
Phylogenomic databases
GeneTreei | ENSGT00940000156131 |
HOGENOMi | CLU_1598261_0_0_1 |
Family and domain databases
Gene3Di | 2.60.40.340, 1 hit |
InterProi | View protein in InterPro IPR008366, NFAT IPR008967, p53-like_TF_DNA-bd IPR011539, RHD_DNA_bind_dom IPR037059, RHD_DNA_bind_dom_sf |
PANTHERi | PTHR12533, PTHR12533, 1 hit |
Pfami | View protein in Pfam PF00554, RHD_DNA_bind, 1 hit |
SUPFAMi | SSF49417, SSF49417, 1 hit |
PROSITEi | View protein in PROSITE PS50254, REL_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
H3BU30-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
LKKDSCGDQF LSVPSPFTWS KPKPGHTPIF RTSSLPPLDW PLPAHFGQCE
60 70 80 90 100
LKIEVQPKTH HRAHYETEGS RGAVKASTGG HPVVKESKIR SSFDVVFDAQ
110 120 130 140 150
LLLSMGKKKV YGKHSRYLTT LTWKLLSIIT TYNFLATSSH MALLTCRSTG
160
KSSPWLGSLS SSKLCIL
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ12968 | NFAC3_HUMAN | Nuclear factor of activated T-cells... | NFATC3 NFAT4 | 1,075 | Annotation score: | ||
H3BRS1 | H3BRS1_HUMAN | Nuclear factor of-activated T-cells... | NFATC3 | 1,060 | Annotation score: | ||
I3L3K7 | I3L3K7_HUMAN | Nuclear factor of-activated T-cells... | NFATC3 | 1,047 | Annotation score: | ||
H3BR83 | H3BR83_HUMAN | Nuclear factor of-activated T-cells... | NFATC3 | 1,053 | Annotation score: | ||
F8VPH9 | F8VPH9_HUMAN | Nuclear factor of-activated T-cells... | NFATC3 | 38 | Annotation score: | ||
H3BRM3 | H3BRM3_HUMAN | Nuclear factor of-activated T-cells... | NFATC3 | 41 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC020978 Genomic DNA No translation available. AC130462 Genomic DNA No translation available. KF456209 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000565750; ENSP00000457441; ENSG00000072736 |
UCSCi | uc059wdk.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC020978 Genomic DNA No translation available. AC130462 Genomic DNA No translation available. KF456209 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | H3BU30 |
PeptideAtlasi | H3BU30 |
PRIDEi | H3BU30 |
ProteomicsDBi | 42811 |
Protocols and materials databases
Antibodypediai | 3861, 294 antibodies |
Genome annotation databases
Ensembli | ENST00000565750; ENSP00000457441; ENSG00000072736 |
UCSCi | uc059wdk.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000072736.18 |
HGNCi | HGNC:7777, NFATC3 |
OpenTargetsi | ENSG00000072736 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156131 |
HOGENOMi | CLU_1598261_0_0_1 |
Miscellaneous databases
ChiTaRSi | NFATC3, human |
Gene expression databases
Bgeei | ENSG00000072736, Expressed in leukocyte and 227 other tissues |
ExpressionAtlasi | H3BU30, baseline and differential |
Family and domain databases
Gene3Di | 2.60.40.340, 1 hit |
InterProi | View protein in InterPro IPR008366, NFAT IPR008967, p53-like_TF_DNA-bd IPR011539, RHD_DNA_bind_dom IPR037059, RHD_DNA_bind_dom_sf |
PANTHERi | PTHR12533, PTHR12533, 1 hit |
Pfami | View protein in Pfam PF00554, RHD_DNA_bind, 1 hit |
SUPFAMi | SSF49417, SSF49417, 1 hit |
PROSITEi | View protein in PROSITE PS50254, REL_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BU30_HUMAN | |
Accessioni | H3BU30Primary (citable) accession number: H3BU30 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | July 11, 2012 | |
Last modified: | August 12, 2020 | |
This is version 50 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |