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Protein
Submitted name:

Eukaryotic translation initiation factor 3 subunit C

Gene

EIF3C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 3 subunit CImported
Gene namesi
Name:EIF3CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000184110.14
HGNCiHGNC:3279 EIF3C

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184110

PTM / Processingi

Proteomic databases

PeptideAtlasiH3BTY8
PRIDEiH3BTY8

Expressioni

Gene expression databases

BgeeiENSG00000184110 Expressed in 167 organ(s), highest expression level in right testis
ExpressionAtlasiH3BTY8 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 79eIF-3c_NInterPro annotationAdd BLAST79

Phylogenomic databases

eggNOGiKOG1076 Eukaryota
ENOG410XRU3 LUCA
GeneTreeiENSGT00390000017900

Family and domain databases

InterProiView protein in InterPro
IPR027516 EIF3C
IPR008905 EIF3C_N_dom
PANTHERiPTHR13937 PTHR13937, 1 hit
PfamiView protein in Pfam
PF05470 eIF-3c_N, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

H3BTY8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKIRDVTKCL EEFELLGKAY GKAKSIVDKE GVPRFYIRIL ADLEDYLNEL
60 70
WEDKEGKKKM NKNNAKALST LRQKIRKYN
Length:79
Mass (Da):9,338
Last modified:October 5, 2016 - v8
Checksum:iD60987D278DA5E27
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99613EIF3C_HUMAN
Eukaryotic translation initiation f...
EIF3C EIF3S8
913Annotation score:
H3BPE4H3BPE4_HUMAN
Eukaryotic translation initiation f...
EIF3C
148Annotation score:
H3BPE3H3BPE3_HUMAN
Eukaryotic translation initiation f...
EIF3C
132Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei79Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145285 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000563139; ENSP00000457389; ENSG00000184110
UCSCiuc059som.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145285 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH3BTY8
PRIDEiH3BTY8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000563139; ENSP00000457389; ENSG00000184110
UCSCiuc059som.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000184110.14
HGNCiHGNC:3279 EIF3C
OpenTargetsiENSG00000184110
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1076 Eukaryota
ENOG410XRU3 LUCA
GeneTreeiENSGT00390000017900

Miscellaneous databases

ChiTaRSiEIF3C human

Gene expression databases

BgeeiENSG00000184110 Expressed in 167 organ(s), highest expression level in right testis
ExpressionAtlasiH3BTY8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027516 EIF3C
IPR008905 EIF3C_N_dom
PANTHERiPTHR13937 PTHR13937, 1 hit
PfamiView protein in Pfam
PF05470 eIF-3c_N, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH3BTY8_HUMAN
AccessioniPrimary (citable) accession number: H3BTY8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: October 5, 2016
Last modified: October 10, 2018
This is version 40 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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