UniProtKB - H3BTQ1 (H3BTQ1_HUMAN)

BLAST

>tr|H3BTQ1|H3BTQ1_HUMAN Trinucleotide repeat-containing gene 6A protein (Fragment) OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=1
XQDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFGV
GNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVAMLNQLSQLNQLSQISQLQRLL
AQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQ
PAMKSFLDNVMPHTTPELQKGPS

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History
Entry version 29 (12 Sep 2018)
Sequence version 1 (18 Apr 2012)
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Protein

Submitted name:

Trinucleotide repeat-containing gene 6A protein

Gene

TNRC6A

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Biological processⁱ

miRNA mediated inhibition of translation Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Trinucleotide repeat-containing gene 6A proteinImported
Gene namesⁱ	Name:TNRC6AImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 16

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000090905.17
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11969 TNRC6A

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000090905

OpenTargetsⁱ

ENSG00000090905

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	H3BTQ1
PeptideAtlas More...PeptideAtlasⁱ	H3BTQ1
PRIDEⁱ	H3BTQ1

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000090905 Expressed in 205 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasⁱ	H3BTQ1 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	H3BTQ1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00410000025966

GeneTreeⁱ

ENSGT00410000025966

Family and domain databases

InterProⁱ	View protein in InterPro IPR033501 TNRC6A
PANTHERⁱ	PTHR13020:SF28 PTHR13020:SF28, 2 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show all Align All

H3BTQ1-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
XQDGIVADES QNMQFMSSQS MKLPPSNSAL PNQALGSIAG LGMQNLNSVR 
        60         70         80         90        100
QNGNPSMFGV GNTAAQPRGM QQPPAQPLSS SQPNLRAQVP PPLLSPQVAM 
       110        120        130        140        150
LNQLSQLNQL SQISQLQRLL AQQQRAQSQR SVPSGNRPQQ DQQGRPLSVQ 
       160        170        180        190        200
QQMMQQSRQL DPNLLVKQQT PPSQQQPLHQ PAMKSFLDNV MPHTTPELQK 

GPS

Length:203

Mass (Da):22,159

Last modified:April 18, 2012 - v1

Checksum:ⁱ3228B4C5F4FDA3BE

Computationally mapped potential isoform sequencesⁱ

There are 5 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q8NDV7	TNR6A_HUMAN	Trinucleotide repeat-containing gen... Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen, Protein GW1) (Glycine-tryptophan protein of 182 kDa)	TNRC6A CAGH26, KIAA1460, TNRC6	1,962	Annotation score:
H7C269	H7C269_HUMAN	Trinucleotide repeat-containing gen... Trinucleotide repeat-containing gene 6A protein	TNRC6A	906	Annotation score:
H3BRT3	H3BRT3_HUMAN	Trinucleotide repeat-containing gen... Trinucleotide repeat-containing gene 6A protein	TNRC6A	160	Annotation score:
I3L218	I3L218_HUMAN	Trinucleotide repeat-containing gen... Trinucleotide repeat-containing gene 6A protein	TNRC6A	96	Annotation score:
I3L3S5	I3L3S5_HUMAN	Trinucleotide repeat-containing gen... Trinucleotide repeat-containing gene 6A protein	TNRC6A	40	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1
Non-terminal residueⁱ	203	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC002565 Genomic DNA No translation available. AC008731 Genomic DNA No translation available. AC010321 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC002565 Genomic DNA No translation available.
AC008731 Genomic DNA No translation available.
AC010321 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000568750; ENSP00000457273; ENSG00000090905
UCSC genome browser More...UCSCⁱ	uc059sfs.1 human

Protein	Similar proteins		Species	Score	Length	Source
H3BTQ1	TNRC6A isoform 13 (Fragment)		PONAB		202	UniRef100_H3BTQ1
TNRC6A isoform 12 (Fragment)		PANTR		202

Protein	Similar proteins		Species	Score	Length	Source
H3BTQ1	TNRC6A isoform 13 (Fragment)		PONAB		202	UniRef90_H3BTQ1
TNRC6A isoform 12 (Fragment)		PANTR		202

Protein	Similar proteins		Species	Score	Length	Source
H3BTQ1	TNRC6A isoform 13 (Fragment)		PONAB		202	UniRef50_H3BTQ1
TNRC6A isoform 12 (Fragment)		PANTR		202

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC002565 Genomic DNA No translation available. AC008731 Genomic DNA No translation available. AC010321 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC002565 Genomic DNA No translation available.
AC008731 Genomic DNA No translation available.
AC010321 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	H3BTQ1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQBⁱ	H3BTQ1
PeptideAtlasⁱ	H3BTQ1
PRIDEⁱ	H3BTQ1

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000568750; ENSP00000457273; ENSG00000090905
UCSCⁱ	uc059sfs.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000090905.17
HGNCⁱ	HGNC:11969 TNRC6A
OpenTargetsⁱ	ENSG00000090905
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

GeneTreeⁱ	ENSGT00410000025966

GeneTreeⁱ

ENSGT00410000025966

Miscellaneous databases

ChiTaRSⁱ	TNRC6A human

ChiTaRSⁱ

TNRC6A human

Gene expression databases

Bgeeⁱ	ENSG00000090905 Expressed in 205 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasⁱ	H3BTQ1 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR033501 TNRC6A
PANTHERⁱ	PTHR13020:SF28 PTHR13020:SF28, 2 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H3BTQ1_HUMAN
Accessionⁱ	H3BTQ1Primary (citable) accession number: H3BTQ1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 18, 2012
	Last sequence update:	April 18, 2012
	Last modified:	September 12, 2018
	This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - H3BTQ1 (H3BTQ1_HUMAN)

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Trinucleotide repeat-containing gene 6A protein

TNRC6A

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ