UniProtKB - H3BSE9 (H3BSE9_HUMAN)
Protein
Submitted name:
Polycystin-1
Gene
PKD1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Polycystin-1Imported |
Gene namesi | Name:PKD1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9008, PKD1 |
VEuPathDBi | HostDB:ENSG00000008710.17 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000008710, Expressed in right hemisphere of cerebellum and 237 other tissues |
ExpressionAtlasi | H3BSE9, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 55 | PKDInterPro annotationAdd BLAST | 55 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 210 – 246 | DisorderedSequence analysisAdd BLAST | 37 |
Keywords - Domaini
TransmembraneARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158702 |
HOGENOMi | CLU_1135706_0_0_1 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR016187, CTDL_fold IPR013783, Ig-like_fold IPR000601, PKD_dom IPR035986, PKD_dom_sf |
Pfami | View protein in Pfam PF00801, PKD, 1 hit |
SUPFAMi | SSF49299, SSF49299, 1 hit SSF56436, SSF56436, 1 hit |
PROSITEi | View protein in PROSITE PS50093, PKD, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
H3BSE9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XDFGDGSAEV DAAGPAASHR YVLPGRYHVT AVLALGAGSA LLGTDVQVEA
60 70 80 90 100
APAALELVCP SSVQSDESLD LSIQNRGGSG LEAAYSIVAL GEEPARAVHP
110 120 130 140 150
LCPSDTEIFP GNGHCYRLVV EKAAWLQAQE QCQAWAGAAL AMVDSPAVQR
160 170 180 190 200
FLVSRVTRHT GPGAGWERVL RPQPGGRRPD AAQFPLGLCG FDTEGGWRVC
210 220 230 240
AELWAPREQH GHHSTGAAGG WRGVHLQPDR VEGRPQGGGH QPDGAD
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP98161 | PKD1_HUMAN | Polycystin-1 | PKD1 | 4,303 | Annotation score: | ||
H3BV77 | H3BV77_HUMAN | Polycystin-1 | PKD1 | 607 | Annotation score: | ||
H3BTE0 | H3BTE0_HUMAN | Polycystin-1 | PKD1 | 1,122 | Annotation score: | ||
H3BTG3 | H3BTG3_HUMAN | Polycystin-1 | PKD1 | 200 | Annotation score: | ||
H3BSE8 | H3BSE8_HUMAN | Polycystin-1 | PKD1 | 155 | Annotation score: | ||
H3BQF4 | H3BQF4_HUMAN | Polycystin-1 | PKD1 | 91 | Annotation score: | ||
I3L4N0 | I3L4N0_HUMAN | Polycystin-1 | PKD1 | 45 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 246 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009065 Genomic DNA No translation available. AC093513 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000488185; ENSP00000456672; ENSG00000008710 |
UCSCi | uc059phw.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009065 Genomic DNA No translation available. AC093513 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | H3BSE9 |
PRIDEi | H3BSE9 |
ProteomicsDBi | 42339 |
Protocols and materials databases
Antibodypediai | 23502, 194 antibodies |
Genome annotation databases
Ensembli | ENST00000488185; ENSP00000456672; ENSG00000008710 |
UCSCi | uc059phw.1, human |
Organism-specific databases
HGNCi | HGNC:9008, PKD1 |
OpenTargetsi | ENSG00000008710 |
VEuPathDBi | HostDB:ENSG00000008710.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158702 |
HOGENOMi | CLU_1135706_0_0_1 |
Miscellaneous databases
ChiTaRSi | PKD1, human |
Gene expression databases
Bgeei | ENSG00000008710, Expressed in right hemisphere of cerebellum and 237 other tissues |
ExpressionAtlasi | H3BSE9, baseline and differential |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR016187, CTDL_fold IPR013783, Ig-like_fold IPR000601, PKD_dom IPR035986, PKD_dom_sf |
Pfami | View protein in Pfam PF00801, PKD, 1 hit |
SUPFAMi | SSF49299, SSF49299, 1 hit SSF56436, SSF56436, 1 hit |
PROSITEi | View protein in PROSITE PS50093, PKD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BSE9_HUMAN | |
Accessioni | H3BSE9Primary (citable) accession number: H3BSE9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | February 10, 2021 | |
This is version 47 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |