UniProtKB - H3BSE8 (H3BSE8_HUMAN)
Protein
Submitted name:
Polycystin-1
Gene
PKD1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Polycystin-1Imported |
Gene namesi | Name:PKD1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9008, PKD1 |
VEuPathDBi | HostDB:ENSG00000008710.17 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000008710, Expressed in right hemisphere of cerebellum and 237 other tissues |
ExpressionAtlasi | H3BSE8, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 11 – 71 | PKDInterPro annotationAdd BLAST | 61 | |
Domaini | 76 – 155 | REJInterPro annotationAdd BLAST | 80 |
Keywords - Domaini
TransmembraneARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158702 |
HOGENOMi | CLU_1708299_0_0_1 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR000601, PKD_dom IPR035986, PKD_dom_sf IPR014010, REJ_dom |
Pfami | View protein in Pfam PF00801, PKD, 1 hit |
SUPFAMi | SSF49299, SSF49299, 1 hit |
PROSITEi | View protein in PROSITE PS50093, PKD, 1 hit PS51111, REJ, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
H3BSE8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XAGVLVDSAV EVAFLWTFGD GEQALHQFQP PYNESFPVPD PSVAQVLVEH
60 70 80 90 100
NVMHTYAAPG EYLLTVLASN AFENLTQQVL IRSGRVPIVS LECVSCKAQA
110 120 130 140 150
VYEVSRSSYV YLEGRCLNCS SGSKRGRWAA RTFSNKTLVL DETTTSTGSA
GMRLV
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP98161 | PKD1_HUMAN | Polycystin-1 | PKD1 | 4,303 | Annotation score: | ||
H3BV77 | H3BV77_HUMAN | Polycystin-1 | PKD1 | 607 | Annotation score: | ||
H3BTE0 | H3BTE0_HUMAN | Polycystin-1 | PKD1 | 1,122 | Annotation score: | ||
H3BTG3 | H3BTG3_HUMAN | Polycystin-1 | PKD1 | 200 | Annotation score: | ||
H3BSE9 | H3BSE9_HUMAN | Polycystin-1 | PKD1 | 246 | Annotation score: | ||
H3BQF4 | H3BQF4_HUMAN | Polycystin-1 | PKD1 | 91 | Annotation score: | ||
I3L4N0 | I3L4N0_HUMAN | Polycystin-1 | PKD1 | 45 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 155 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009065 Genomic DNA No translation available. AC093513 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000483024; ENSP00000456670; ENSG00000008710 |
UCSCi | uc059phv.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009065 Genomic DNA No translation available. AC093513 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | H3BSE8 |
PRIDEi | H3BSE8 |
ProteomicsDBi | 42338 |
Protocols and materials databases
Antibodypediai | 23502, 194 antibodies |
Genome annotation databases
Ensembli | ENST00000483024; ENSP00000456670; ENSG00000008710 |
UCSCi | uc059phv.1, human |
Organism-specific databases
HGNCi | HGNC:9008, PKD1 |
OpenTargetsi | ENSG00000008710 |
VEuPathDBi | HostDB:ENSG00000008710.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158702 |
HOGENOMi | CLU_1708299_0_0_1 |
Miscellaneous databases
ChiTaRSi | PKD1, human |
Gene expression databases
Bgeei | ENSG00000008710, Expressed in right hemisphere of cerebellum and 237 other tissues |
ExpressionAtlasi | H3BSE8, baseline and differential |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR000601, PKD_dom IPR035986, PKD_dom_sf IPR014010, REJ_dom |
Pfami | View protein in Pfam PF00801, PKD, 1 hit |
SUPFAMi | SSF49299, SSF49299, 1 hit |
PROSITEi | View protein in PROSITE PS50093, PKD, 1 hit PS51111, REJ, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BSE8_HUMAN | |
Accessioni | H3BSE8Primary (citable) accession number: H3BSE8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | February 10, 2021 | |
This is version 44 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |