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Protein

Gamma-tubulin complex component

Gene

TUBGCP4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-tubulin complex componentUniRule annotation
Gene namesi
Name:TUBGCP4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000137822.12
HGNCiHGNC:16691 TUBGCP4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000137822

PTM / Processingi

Proteomic databases

EPDiH3BS59
MaxQBiH3BS59
PeptideAtlasiH3BS59
PRIDEiH3BS59

Expressioni

Gene expression databases

BgeeiENSG00000137822 Expressed in 205 organ(s), highest expression level in frontal cortex
ExpressionAtlasiH3BS59 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the TUBGCP family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2065 Eukaryota
ENOG410XPES LUCA
GeneTreeiENSGT00850000132278

Family and domain databases

InterProiView protein in InterPro
IPR007259 GCP
PANTHERiPTHR19302 PTHR19302, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H3BS59-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
FLSNLLAQSF ILLKPVFHCL NEILDLCHSF CSLVSQNLGP LDERGAAQLS
60 70 80 90 100
ILVKGFSRQS SLLFKILSSV RNHQINSDLA QLLLRLDYNK YYTQAGGTLG

RKKPC
Length:105
Mass (Da):11,753
Last modified:April 18, 2012 - v1
Checksum:i32857E22FE74AB8F
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UGJ1GCP4_HUMAN
Gamma-tubulin complex component 4
TUBGCP4 76P, GCP4
667Annotation score:
H3BPU4H3BPU4_HUMAN
Gamma-tubulin complex component
TUBGCP4
397Annotation score:
H3BQY4H3BQY4_HUMAN
Gamma-tubulin complex component
TUBGCP4
103Annotation score:
H3BN56H3BN56_HUMAN
Gamma-tubulin complex component
TUBGCP4
82Annotation score:
H3BNL9H3BNL9_HUMAN
Gamma-tubulin complex component
TUBGCP4
171Annotation score:
H3BQ12H3BQ12_HUMAN
Gamma-tubulin complex component 4
TUBGCP4
66Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018924 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000565548; ENSP00000456550; ENSG00000137822
UCSCiuc059ijk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018924 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH3BS59
MaxQBiH3BS59
PeptideAtlasiH3BS59
PRIDEiH3BS59

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000565548; ENSP00000456550; ENSG00000137822
UCSCiuc059ijk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000137822.12
HGNCiHGNC:16691 TUBGCP4
OpenTargetsiENSG00000137822
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2065 Eukaryota
ENOG410XPES LUCA
GeneTreeiENSGT00850000132278

Miscellaneous databases

ChiTaRSiTUBGCP4 human

Gene expression databases

BgeeiENSG00000137822 Expressed in 205 organ(s), highest expression level in frontal cortex
ExpressionAtlasiH3BS59 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007259 GCP
PANTHERiPTHR19302 PTHR19302, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH3BS59_HUMAN
AccessioniPrimary (citable) accession number: H3BS59
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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