UniProtKB - H3BRT3 (H3BRT3_HUMAN)
Protein
Submitted name:
Trinucleotide repeat-containing gene 6A protein
Gene
TNRC6A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- nucleic acid binding Source: InterPro
GO - Biological processi
- miRNA mediated inhibition of translation Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Trinucleotide repeat-containing gene 6A proteinImported |
Gene namesi | Name:TNRC6AImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000090905.17 |
HGNCi | HGNC:11969, TNRC6A |
PTM / Processingi
Proteomic databases
MaxQBi | H3BRT3 |
PeptideAtlasi | H3BRT3 |
PRIDEi | H3BRT3 |
ProteomicsDBi | 42157 |
Expressioni
Gene expression databases
Bgeei | ENSG00000090905, Expressed in cerebellar vermis and 215 other tissues |
ExpressionAtlasi | H3BRT3, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 92 | TNRC6-PABC_bdgInterPro annotationAdd BLAST | 92 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 22 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 36 – 65 | DisorderedSequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 40 – 54 | Pro-richSequence analysisAdd BLAST | 15 |
Phylogenomic databases
GeneTreei | ENSGT00940000158180 |
HOGENOMi | CLU_1656141_0_0_1 |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR032226, TNRC6_PABC-bd IPR033501, TNRC6A |
PANTHERi | PTHR13020:SF28, PTHR13020:SF28, 1 hit |
Pfami | View protein in Pfam PF16608, TNRC6-PABC_bdg, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
H3BRT3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
STAQSTSARN SDSKLTWSPG SVTNTSLAHE LWKVPLPPKN ITAPSRPPPG
60 70 80 90 100
LTGQKPPLST WDNSPLRIGG GWGNSDARYT PGSSWGESSS GRITNWLVLK
110 120 130 140 150
NLTPQIDGST LRTLCMQHGP LITFHLNLPH GNALVRYSSK EEVVKAQKSL
160
HISDLFLLTL
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8NDV7 | TNR6A_HUMAN | Trinucleotide repeat-containing gen... | TNRC6A CAGH26, KIAA1460, TNRC6 | 1,962 | Annotation score: | ||
H7C269 | H7C269_HUMAN | Trinucleotide repeat-containing gen... | TNRC6A | 906 | Annotation score: | ||
H3BTQ1 | H3BTQ1_HUMAN | Trinucleotide repeat-containing gen... | TNRC6A | 203 | Annotation score: | ||
I3L218 | I3L218_HUMAN | Trinucleotide repeat-containing gen... | TNRC6A | 96 | Annotation score: | ||
I3L3S5 | I3L3S5_HUMAN | Trinucleotide repeat-containing gen... | TNRC6A | 40 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC002565 Genomic DNA No translation available. AC008731 Genomic DNA No translation available. AC010321 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000569098; ENSP00000456394; ENSG00000090905 |
UCSCi | uc059sfw.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC002565 Genomic DNA No translation available. AC008731 Genomic DNA No translation available. AC010321 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | H3BRT3 |
PeptideAtlasi | H3BRT3 |
PRIDEi | H3BRT3 |
ProteomicsDBi | 42157 |
Protocols and materials databases
Antibodypediai | 12719, 107 antibodies |
Genome annotation databases
Ensembli | ENST00000569098; ENSP00000456394; ENSG00000090905 |
UCSCi | uc059sfw.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000090905.17 |
HGNCi | HGNC:11969, TNRC6A |
OpenTargetsi | ENSG00000090905 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158180 |
HOGENOMi | CLU_1656141_0_0_1 |
Miscellaneous databases
ChiTaRSi | TNRC6A, human |
Gene expression databases
Bgeei | ENSG00000090905, Expressed in cerebellar vermis and 215 other tissues |
ExpressionAtlasi | H3BRT3, baseline and differential |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR032226, TNRC6_PABC-bd IPR033501, TNRC6A |
PANTHERi | PTHR13020:SF28, PTHR13020:SF28, 1 hit |
Pfami | View protein in Pfam PF16608, TNRC6-PABC_bdg, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BRT3_HUMAN | |
Accessioni | H3BRT3Primary (citable) accession number: H3BRT3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | December 2, 2020 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |