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Protein
Submitted name:

Target of rapamycin complex subunit LST8

Gene

MLST8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Target of rapamycin complex subunit LST8Imported
Gene namesi
Name:MLST8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000167965.17
HGNCiHGNC:24825 MLST8

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000167965

PTM / Processingi

Proteomic databases

MaxQBiH3BR25
PeptideAtlasiH3BR25
PRIDEiH3BR25

Expressioni

Gene expression databases

BgeeiENSG00000167965 Expressed in 203 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiH3BR25 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH3BR25
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 166WD_REPEATS_REGIONInterPro annotationAdd BLAST166
Repeati87 – 128WDPROSITE-ProRule annotationAdd BLAST42
Repeati137 – 166WDPROSITE-ProRule annotationAdd BLAST30

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0315 Eukaryota
ENOG410XPVD LUCA
GeneTreeiENSGT00390000014795

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR037588 MLST8
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19842 PTHR19842, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 2 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 3 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

H3BR25-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTSPGTVGS DPVILATAGY DHTVRFWQAH SGICTRTVQH QDSQVNALEV
60 70 80 90 100
TPDRSMIAAA VQPVSLGYQH IRMYDLNSNN PNPIISYDGV NKNIASVGFH
110 120 130 140 150
EDGRWMYTGG EDCTARIWDL RSRNLQCQRI FQVNAPINCV CLHPNQAELI
160
VGDQSGAIHI WDLKTD
Length:166
Mass (Da):18,421
Last modified:April 18, 2012 - v1
Checksum:iEF0BE62083B6A8A4
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9BVC4LST8_HUMAN
Target of rapamycin complex subunit...
MLST8 GBL, LST8
326Annotation score:
A0A0A0MR05A0A0A0MR05_HUMAN
Target of rapamycin complex subunit...
MLST8
327Annotation score:
H3BPT1H3BPT1_HUMAN
Target of rapamycin complex subunit...
MLST8
198Annotation score:
H3BN58H3BN58_HUMAN
Target of rapamycin complex subunit...
MLST8
202Annotation score:
H3BPU5H3BPU5_HUMAN
Target of rapamycin complex subunit...
MLST8
131Annotation score:
H3BSZ4H3BSZ4_HUMAN
Target of rapamycin complex subunit...
MLST8
275Annotation score:
H3BM50H3BM50_HUMAN
Target of rapamycin complex subunit...
MLST8
116Annotation score:
I3L2E7I3L2E7_HUMAN
Target of rapamycin complex subunit...
MLST8
71Annotation score:
H3BQ74H3BQ74_HUMAN
Target of rapamycin complex subunit...
MLST8
51Annotation score:
H3BR38H3BR38_HUMAN
Target of rapamycin complex subunit...
MLST8
72Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei166Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009065 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000562479; ENSP00000456046; ENSG00000167965
UCSCiuc059pjg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009065 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH3BR25
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH3BR25
PeptideAtlasiH3BR25
PRIDEiH3BR25

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000562479; ENSP00000456046; ENSG00000167965
UCSCiuc059pjg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000167965.17
HGNCiHGNC:24825 MLST8
OpenTargetsiENSG00000167965
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0315 Eukaryota
ENOG410XPVD LUCA
GeneTreeiENSGT00390000014795

Miscellaneous databases

ChiTaRSiMLST8 human

Gene expression databases

BgeeiENSG00000167965 Expressed in 203 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiH3BR25 baseline and differential

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR037588 MLST8
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19842 PTHR19842, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 2 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 3 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH3BR25_HUMAN
AccessioniPrimary (citable) accession number: H3BR25
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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