UniProtKB - H3BPI9 (H3BPI9_HUMAN)
Protein
Receptor protein serine/threonine kinase
Gene
AMHR2
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- EC:2.7.11.30ARBA annotation
- [receptor-protein]-L-threonine + ATP = [receptor-protein]-O-phospho-L-threonine + ADP + H+ARBA annotationEC:2.7.11.30ARBA annotation
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- transmembrane receptor protein serine/threonine kinase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinaseARBA annotation, Transferase |
Ligand | ATP-bindingARBA annotation, ManganeseARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Receptor protein serine/threonine kinaseARBA annotation (EC:2.7.11.30ARBA annotation) |
Gene namesi | Name:AMHR2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000135409.10 |
HGNCi | HGNC:465, AMHR2 |
Subcellular locationi
Other locations
- membrane Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSG00000135409, Expressed in left adrenal gland and 96 other tissues |
ExpressionAtlasi | H3BPI9, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 172 | Protein kinaseInterPro annotationAdd BLAST | 172 |
Sequence similaritiesi
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000160885 |
HOGENOMi | CLU_1558800_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR000333, TGFB_receptor |
PANTHERi | PTHR23255, PTHR23255, 1 hit |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
H3BPI9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALSLAQGLA FLHEERWQNG QYKPGIAHRD LSSQNVLIRE DGSCAIGDLG
60 70 80 90 100
LALVLPGLTQ PPAWTPTQPQ GPAAIMEAGT QRYMAPELLD KTLDLQDWGM
110 120 130 140 150
ALRRADIYSL ALLLWEILSR CPDLRPDSSP PPFQLAYEAE LGNTPTSDEL
160 170
WALAVQERRR PYIPSTWRCF AT
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ16671 | AMHR2_HUMAN | Anti-Muellerian hormone type-2 rece... | AMHR2 AMHR, MISR2 | 573 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 172 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068889 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000550839; ENSP00000455338; ENSG00000135409 |
UCSCi | uc058opt.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068889 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | H3BPI9 |
ProteomicsDBi | 41507 |
Protocols and materials databases
Antibodypediai | 27053, 315 antibodies |
Genome annotation databases
Ensembli | ENST00000550839; ENSP00000455338; ENSG00000135409 |
UCSCi | uc058opt.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000135409.10 |
HGNCi | HGNC:465, AMHR2 |
OpenTargetsi | ENSG00000135409 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000160885 |
HOGENOMi | CLU_1558800_0_0_1 |
Gene expression databases
Bgeei | ENSG00000135409, Expressed in left adrenal gland and 96 other tissues |
ExpressionAtlasi | H3BPI9, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR000333, TGFB_receptor |
PANTHERi | PTHR23255, PTHR23255, 1 hit |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BPI9_HUMAN | |
Accessioni | H3BPI9Primary (citable) accession number: H3BPI9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | December 2, 2020 | |
This is version 59 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |