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Protein
Submitted name:

CCR4-NOT transcription complex subunit 1

Gene

CNOT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
CCR4-NOT transcription complex subunit 1Imported
Gene namesi
Name:CNOT1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000125107.16
HGNCiHGNC:7877 CNOT1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000125107

PTM / Processingi

Proteomic databases

MaxQBiH3BNB1
PeptideAtlasiH3BNB1
PRIDEiH3BNB1

Expressioni

Gene expression databases

BgeeiENSG00000125107 Expressed in 232 organ(s), highest expression level in testis
ExpressionAtlasiH3BNB1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH3BNB1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 183DUF3819InterPro annotationAdd BLAST90

Phylogenomic databases

GeneTreeiENSGT00390000014869

Family and domain databases

InterProiView protein in InterPro
IPR024557 CCR4-Not_Not1su_DUF3819
PfamiView protein in Pfam
PF12842 DUF3819, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

H3BNB1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XAELHQEHDL KDKDRLKNLD EQLSAPKKDV KQPEELPPIT TTTTSTTPAT
60 70 80 90 100
NTTCTATVPP QPQYSYHDIN VYSLAGLAPH ITLNPTIPLF QAHPQLKQCV
110 120 130 140 150
RQAIERAVQE LVHPVVDRSI KIAMTTCEQI VRKDFALDSE ESRMRIAAHH
160 170 180
MMRNLTAGMA MITCREPLLM SISTNLKNSF ASALR
Length:185
Mass (Da):20,731
Last modified:April 18, 2012 - v1
Checksum:iB985853734B93FA3
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A5YKK6CNOT1_HUMAN
CCR4-NOT transcription complex subu...
CNOT1 CDC39, KIAA1007, NOT1, AD-005
2,376Annotation score:
H3BR89H3BR89_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
193Annotation score:
H3BMH0H3BMH0_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
277Annotation score:
H3BTH2H3BTH2_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
68Annotation score:
H3BMZ2H3BMZ2_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
439Annotation score:
H3BVC9H3BVC9_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
241Annotation score:
H3BT18H3BT18_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
62Annotation score:
H3BPF1H3BPF1_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
25Annotation score:
H3BU44H3BU44_HUMAN
CCR4-NOT transcription complex subu...
CNOT1
96Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei185Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009118 Genomic DNA No translation available.
AC010287 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000567133; ENSP00000454763; ENSG00000125107
UCSCiuc059vdg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009118 Genomic DNA No translation available.
AC010287 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH3BNB1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH3BNB1
PeptideAtlasiH3BNB1
PRIDEiH3BNB1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000567133; ENSP00000454763; ENSG00000125107
UCSCiuc059vdg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000125107.16
HGNCiHGNC:7877 CNOT1
OpenTargetsiENSG00000125107
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000014869

Miscellaneous databases

ChiTaRSiCNOT1 human

Gene expression databases

BgeeiENSG00000125107 Expressed in 232 organ(s), highest expression level in testis
ExpressionAtlasiH3BNB1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR024557 CCR4-Not_Not1su_DUF3819
PfamiView protein in Pfam
PF12842 DUF3819, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH3BNB1_HUMAN
AccessioniPrimary (citable) accession number: H3BNB1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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