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Protein
Submitted name:

Myosin regulatory light chain 2, skeletal muscle isoform

Gene

MYLPF

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi38 – 49PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin regulatory light chain 2, skeletal muscle isoformImported
Gene namesi
Name:MYLPFImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000180209.11
HGNCiHGNC:29824 MYLPF

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000180209

PTM / Processingi

Proteomic databases

PeptideAtlasiH3BN54
PRIDEiH3BN54

Expressioni

Gene expression databases

BgeeiENSG00000180209 Expressed in 121 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiH3BN54 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH3BN54
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 60EF-handInterPro annotationAdd BLAST36
Domaini95 – 130EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG0031 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00760000119196

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13405 EF-hand_6, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 2 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

H3BN54-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPKRAKRRT VEGGSSSVFS MFDQTQIQEF KEAFTVIDQN RDGIIDKEDL
60 70 80 90 100
RDTFAAMGRL NVKNEELDAM MKEASGPINF TVFLTMFGEK LKGADPEDVI
110 120 130
TGAFKVLDPE GKGTIKKKFL EELLTTQCDR FSQEE
Length:135
Mass (Da):15,222
Last modified:April 18, 2012 - v1
Checksum:i3092FD8AAEA0EA28
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96A32MLRS_HUMAN
Myosin regulatory light chain 2, sk...
MYLPF
169Annotation score:
H3BPK4H3BPK4_HUMAN
Myosin regulatory light chain 2, sk...
MYLPF
199Annotation score:
H3BML9H3BML9_HUMAN
Myosin regulatory light chain 2, sk...
MYLPF
118Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei135Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106782 Genomic DNA No translation available.
AC127457 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000568749; ENSP00000454694; ENSG00000180209
UCSCiuc059tdn.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106782 Genomic DNA No translation available.
AC127457 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH3BN54
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH3BN54
PRIDEiH3BN54

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000568749; ENSP00000454694; ENSG00000180209
UCSCiuc059tdn.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000180209.11
HGNCiHGNC:29824 MYLPF
OpenTargetsiENSG00000180209
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0031 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00760000119196

Miscellaneous databases

ChiTaRSiMYLPF human

Gene expression databases

BgeeiENSG00000180209 Expressed in 121 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiH3BN54 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13405 EF-hand_6, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 2 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH3BN54_HUMAN
AccessioniPrimary (citable) accession number: H3BN54
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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