UniProtKB - H3BMQ5 (H3BMQ5_HUMAN)
Protein
RNA helicase
Gene
DDX19B
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- nucleic acid binding Source: InterPro
- RNA helicase activity Source: UniProtKB-EC
Keywordsi
Molecular function | HydrolaseARBA annotation |
Ligand | ATP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:DDX19BImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000157349.16 |
HGNCi | HGNC:2742, DDX19B |
PTM / Processingi
Proteomic databases
EPDi | H3BMQ5 |
MaxQBi | H3BMQ5 |
PeptideAtlasi | H3BMQ5 |
PRIDEi | H3BMQ5 |
ProteomicsDBi | 40975 |
Expressioni
Gene expression databases
Bgeei | ENSG00000157349, Expressed in testis and 148 other tissues |
ExpressionAtlasi | H3BMQ5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 79 – 107 | Q_MOTIFInterPro annotationAdd BLAST | 29 | |
Domaini | 112 – 233 | Helicase ATP-bindingInterPro annotationAdd BLAST | 122 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 79 – 107 | Q motifPROSITE-ProRule annotationAdd BLAST | 29 |
Phylogenomic databases
eggNOGi | KOG0332, Eukaryota |
GeneTreei | ENSGT00940000154417 |
Family and domain databases
InterProi | View protein in InterPro IPR011545, DEAD/DEAH_box_helicase_dom IPR014001, Helicase_ATP-bd IPR027417, P-loop_NTPase IPR014014, RNA_helicase_DEAD_Q_motif |
Pfami | View protein in Pfam PF00270, DEAD, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS51192, HELICASE_ATP_BIND_1, 1 hit PS51195, Q_MOTIF, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
H3BMQ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQLREKLSNL HLKEEKIKPD TNGAVVKTNA NAEKTDEEEK EDRAAQSLLN
60 70 80 90 100
KLIRSNLVDN TNQVEVLQRD PNSPLYSVKS FEELRLKPQL LQGVYAMGFN
110 120 130 140 150
RPSKIQENAL PLMLAEPPQN LIAQSQSGTG KTAAFVLAML SQVEPANKYP
160 170 180 190 200
QCLCLSPTYE LALQTGKVIE QMGKFYPELK LAYAVRGNKL ERGQKISEQI
210 220 230
VIGTPGTVLD WCSKLKFIDP KKIKVFVLDE ADV
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UMR2 | DD19B_HUMAN | ATP-dependent RNA helicase DDX19B | DDX19B DBP5, DDX19, TDBP | 479 | Annotation score: | ||
H3BQK0 | H3BQK0_HUMAN | RNA helicase | DDX19B hCG_1998531 | 484 | Annotation score: | ||
H3BN59 | H3BN59_HUMAN | RNA helicase | 261 | Annotation score: | |||
F6QDS0 | F6QDS0_HUMAN | RNA helicase | hCG_2043426 | 479 | Annotation score: | ||
H3BPV3 | H3BPV3_HUMAN | ATP-dependent RNA helicase DDX19B | DDX19B | 30 | Annotation score: | ||
H3BUH0 | H3BUH0_HUMAN | ATP-dependent RNA helicase DDX19B | DDX19B | 48 | Annotation score: | ||
H3BTX1 | H3BTX1_HUMAN | ATP-dependent RNA helicase DDX19B | DDX19B | 41 | Annotation score: | ||
H3BMV7 | H3BMV7_HUMAN | ATP-dependent RNA helicase DDX19B | DDX19B | 32 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 233 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012184 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000566216; ENSP00000454495; ENSG00000157349 |
UCSCi | uc059wop.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012184 Genomic DNA No translation available. |
3D structure databases
SMRi | H3BMQ5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000454699 |
Proteomic databases
EPDi | H3BMQ5 |
MaxQBi | H3BMQ5 |
PeptideAtlasi | H3BMQ5 |
PRIDEi | H3BMQ5 |
ProteomicsDBi | 40975 |
Protocols and materials databases
Antibodypediai | 16335, 306 antibodies |
Genome annotation databases
Ensembli | ENST00000566216; ENSP00000454495; ENSG00000157349 |
UCSCi | uc059wop.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000157349.16 |
HGNCi | HGNC:2742, DDX19B |
OpenTargetsi | ENSG00000157349 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0332, Eukaryota |
GeneTreei | ENSGT00940000154417 |
Miscellaneous databases
ChiTaRSi | DDX19B, human |
Gene expression databases
Bgeei | ENSG00000157349, Expressed in testis and 148 other tissues |
ExpressionAtlasi | H3BMQ5, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011545, DEAD/DEAH_box_helicase_dom IPR014001, Helicase_ATP-bd IPR027417, P-loop_NTPase IPR014014, RNA_helicase_DEAD_Q_motif |
Pfami | View protein in Pfam PF00270, DEAD, 1 hit |
SMARTi | View protein in SMART SM00487, DEXDc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS51192, HELICASE_ATP_BIND_1, 1 hit PS51195, Q_MOTIF, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BMQ5_HUMAN | |
Accessioni | H3BMQ5Primary (citable) accession number: H3BMQ5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | October 7, 2020 | |
This is version 50 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |