UniProtKB - H3BMQ5 (H3BMQ5_HUMAN)

BLAST

>tr|H3BMQ5|H3BMQ5_HUMAN ATP-dependent RNA helicase DDX19B (Fragment) OS=Homo sapiens OX=9606 GN=DDX19B PE=1 SV=1
MQLREKLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDN
TNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQN
LIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELK
LAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADV

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History
Entry version 40 (12 Sep 2018)
Sequence version 1 (18 Apr 2012)
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Protein

Submitted name:

ATP-dependent RNA helicase DDX19B

Gene

DDX19B

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: InterPro
nucleic acid binding Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ATP-dependent RNA helicase DDX19BImported
Gene namesⁱ	Name:DDX19BImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 16

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000157349.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:2742 DDX19B

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000157349

OpenTargetsⁱ

ENSG00000157349

PTM / Processingⁱ

Proteomic databases

EPDⁱ	H3BMQ5
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	H3BMQ5
PeptideAtlas More...PeptideAtlasⁱ	H3BMQ5
PRIDEⁱ	H3BMQ5

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000157349 Expressed in 131 organ(s), highest expression level in testis
ExpressionAtlasⁱ	H3BMQ5 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	H3BMQ5
SMRⁱ	H3BMQ5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	79 – 107	Q_MOTIFInterPro annotationAdd BLAST		29
Domainⁱ	112 – 233	Helicase ATP-bindingInterPro annotationAdd BLAST		122

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	79 – 107	Q motifPROSITE-ProRule annotationAdd BLAST		29

Phylogenomic databases

eggNOGⁱ	KOG0332 Eukaryota ENOG410XRGX LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063236

Family and domain databases

InterProⁱ	View protein in InterPro IPR011545 DEAD/DEAH_box_helicase_dom IPR014001 Helicase_ATP-bd IPR027417 P-loop_NTPase IPR014014 RNA_helicase_DEAD_Q_motif
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00270 DEAD, 1 hit
SMARTⁱ	View protein in SMART SM00487 DEXDc, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
PROSITEⁱ	View protein in PROSITE PS51192 HELICASE_ATP_BIND_1, 1 hit PS51195 Q_MOTIF, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show all Align All

H3BMQ5-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MQLREKLSNL HLKEEKIKPD TNGAVVKTNA NAEKTDEEEK EDRAAQSLLN 
        60         70         80         90        100
KLIRSNLVDN TNQVEVLQRD PNSPLYSVKS FEELRLKPQL LQGVYAMGFN 
       110        120        130        140        150
RPSKIQENAL PLMLAEPPQN LIAQSQSGTG KTAAFVLAML SQVEPANKYP 
       160        170        180        190        200
QCLCLSPTYE LALQTGKVIE QMGKFYPELK LAYAVRGNKL ERGQKISEQI 
       210        220        230 
VIGTPGTVLD WCSKLKFIDP KKIKVFVLDE ADV

Length:233

Mass (Da):26,083

Last modified:April 18, 2012 - v1

Checksum:ⁱ0084B9111ADBD53B

Computationally mapped potential isoform sequencesⁱ

There are 8 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q9UMR2	DD19B_HUMAN	ATP-dependent RNA helicase DDX19B ATP-dependent RNA helicase DDX19B, EC 3.6.4.13 (DEAD box RNA helicase DEAD5) (DEAD box protein 19B)	DDX19B DBP5, DDX19, TDBP	479	Annotation score:
H3BQK0	H3BQK0_HUMAN	ATP-dependent RNA helicase DDX19B ATP-dependent RNA helicase DDX19B (HCG1998531, isoform CRA_g)	DDX19B hCG_1998531	484	Annotation score:
F6QDS0	F6QDS0_HUMAN	HCG2043426, isoform CRA_b HCG2043426, isoform CRA_b	hCG_2043426	479	Annotation score:
H3BN59	H3BN59_HUMAN	Uncharacterized protein Uncharacterized protein		261	Annotation score:
H3BTX1	H3BTX1_HUMAN	ATP-dependent RNA helicase DDX19B ATP-dependent RNA helicase DDX19B	DDX19B	41	Annotation score:
H3BMV7	H3BMV7_HUMAN	ATP-dependent RNA helicase DDX19B ATP-dependent RNA helicase DDX19B	DDX19B	32	Annotation score:
H3BPV3	H3BPV3_HUMAN	ATP-dependent RNA helicase DDX19B ATP-dependent RNA helicase DDX19B	DDX19B	30	Annotation score:
H3BUH0	H3BUH0_HUMAN	ATP-dependent RNA helicase DDX19B ATP-dependent RNA helicase DDX19B	DDX19B	48	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	233	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC012184 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC012184 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000566216; ENSP00000454495; ENSG00000157349
UCSC genome browser More...UCSCⁱ	uc059wop.1 human

Protein	Similar proteins		Species	Score	Length	Source
H3BMQ5	Uncharacterized protein (Fragment)		Micrurus lemniscatus lemniscatus		235	UniRef90_H3BMQ5
DDX19B isoform 11 (Fragment)		PONAB		233
UPI0007380A1B		VICPA		278
UPI000C87C766		PTEVA		265

Protein	Similar proteins		Species	Score	Length	Source
H3BMQ5	Uncharacterized protein (Fragment)		Micrurus lemniscatus lemniscatus		235	UniRef50_H3BMQ5
DDX19B isoform 11 (Fragment)		PONAB		233
DEAD-box helicase Dbp80-like		AGRPL		347
UPI0007380A1B		VICPA		278
UPI000C87C766		PTEVA		265

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC012184 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC012184 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	H3BMQ5
SMRⁱ	H3BMQ5
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	H3BMQ5
MaxQBⁱ	H3BMQ5
PeptideAtlasⁱ	H3BMQ5
PRIDEⁱ	H3BMQ5

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000566216; ENSP00000454495; ENSG00000157349
UCSCⁱ	uc059wop.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000157349.16
HGNCⁱ	HGNC:2742 DDX19B
OpenTargetsⁱ	ENSG00000157349
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0332 Eukaryota ENOG410XRGX LUCA
GeneTreeⁱ	ENSGT00530000063236

Miscellaneous databases

ChiTaRSⁱ	DDX19B human

ChiTaRSⁱ

DDX19B human

Gene expression databases

Bgeeⁱ	ENSG00000157349 Expressed in 131 organ(s), highest expression level in testis
ExpressionAtlasⁱ	H3BMQ5 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR011545 DEAD/DEAH_box_helicase_dom IPR014001 Helicase_ATP-bd IPR027417 P-loop_NTPase IPR014014 RNA_helicase_DEAD_Q_motif
Pfamⁱ	View protein in Pfam PF00270 DEAD, 1 hit
SMARTⁱ	View protein in SMART SM00487 DEXDc, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
PROSITEⁱ	View protein in PROSITE PS51192 HELICASE_ATP_BIND_1, 1 hit PS51195 Q_MOTIF, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	H3BMQ5_HUMAN
Accessionⁱ	H3BMQ5Primary (citable) accession number: H3BMQ5
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 18, 2012
	Last sequence update:	April 18, 2012
	Last modified:	September 12, 2018
	This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

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UniRef

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Annotation systems

Supporting data

UniProtKB - H3BMQ5 (H3BMQ5_HUMAN)

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ATP-dependent RNA helicase DDX19B

DDX19B

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Motif

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ