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Protein
Submitted name:

ATP-dependent RNA helicase DDX19B

Gene

DDX19B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent RNA helicase DDX19BImported
Gene namesi
Name:DDX19BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000157349.16
HGNCiHGNC:2742 DDX19B

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000157349

PTM / Processingi

Proteomic databases

EPDiH3BMQ5
MaxQBiH3BMQ5
PeptideAtlasiH3BMQ5
PRIDEiH3BMQ5

Expressioni

Gene expression databases

BgeeiENSG00000157349 Expressed in 131 organ(s), highest expression level in testis
ExpressionAtlasiH3BMQ5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH3BMQ5
SMRiH3BMQ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 107Q_MOTIFInterPro annotationAdd BLAST29
Domaini112 – 233Helicase ATP-bindingInterPro annotationAdd BLAST122

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi79 – 107Q motifPROSITE-ProRule annotationAdd BLAST29

Phylogenomic databases

eggNOGiKOG0332 Eukaryota
ENOG410XRGX LUCA
GeneTreeiENSGT00530000063236

Family and domain databases

InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

H3BMQ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQLREKLSNL HLKEEKIKPD TNGAVVKTNA NAEKTDEEEK EDRAAQSLLN
60 70 80 90 100
KLIRSNLVDN TNQVEVLQRD PNSPLYSVKS FEELRLKPQL LQGVYAMGFN
110 120 130 140 150
RPSKIQENAL PLMLAEPPQN LIAQSQSGTG KTAAFVLAML SQVEPANKYP
160 170 180 190 200
QCLCLSPTYE LALQTGKVIE QMGKFYPELK LAYAVRGNKL ERGQKISEQI
210 220 230
VIGTPGTVLD WCSKLKFIDP KKIKVFVLDE ADV
Length:233
Mass (Da):26,083
Last modified:April 18, 2012 - v1
Checksum:i0084B9111ADBD53B
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UMR2DD19B_HUMAN
ATP-dependent RNA helicase DDX19B
DDX19B DBP5, DDX19, TDBP
479Annotation score:
H3BQK0H3BQK0_HUMAN
ATP-dependent RNA helicase DDX19B
DDX19B hCG_1998531
484Annotation score:
F6QDS0F6QDS0_HUMAN
HCG2043426, isoform CRA_b
hCG_2043426
479Annotation score:
H3BN59H3BN59_HUMAN
Uncharacterized protein
261Annotation score:
H3BTX1H3BTX1_HUMAN
ATP-dependent RNA helicase DDX19B
DDX19B
41Annotation score:
H3BMV7H3BMV7_HUMAN
ATP-dependent RNA helicase DDX19B
DDX19B
32Annotation score:
H3BPV3H3BPV3_HUMAN
ATP-dependent RNA helicase DDX19B
DDX19B
30Annotation score:
H3BUH0H3BUH0_HUMAN
ATP-dependent RNA helicase DDX19B
DDX19B
48Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei233Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012184 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000566216; ENSP00000454495; ENSG00000157349
UCSCiuc059wop.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012184 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH3BMQ5
SMRiH3BMQ5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH3BMQ5
MaxQBiH3BMQ5
PeptideAtlasiH3BMQ5
PRIDEiH3BMQ5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000566216; ENSP00000454495; ENSG00000157349
UCSCiuc059wop.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000157349.16
HGNCiHGNC:2742 DDX19B
OpenTargetsiENSG00000157349
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0332 Eukaryota
ENOG410XRGX LUCA
GeneTreeiENSGT00530000063236

Miscellaneous databases

ChiTaRSiDDX19B human

Gene expression databases

BgeeiENSG00000157349 Expressed in 131 organ(s), highest expression level in testis
ExpressionAtlasiH3BMQ5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51195 Q_MOTIF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH3BMQ5_HUMAN
AccessioniPrimary (citable) accession number: H3BMQ5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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