UniProtKB - H3BMN2 (H3BMN2_HUMAN)
Protein
Secretory carrier-associated membrane protein
Gene
SCAMP2
Organism
Homo sapiens (Human)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
GO - Biological processi
- protein transport Source: InterPro
Keywordsi
Biological process | TransportUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Secretory carrier-associated membrane proteinUniRule annotationShort name: Secretory carrier membrane proteinUniRule annotation |
Gene namesi | Name:SCAMP2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:10564, SCAMP2 |
VEuPathDBi | HostDB:ENSG00000140497.16 |
Subcellular locationi
Other locations
- Membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 24 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 36 – 56 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 68 – 89 | HelicalUniRule annotationAdd BLAST | 22 |
Keywords - Cellular componenti
MembranePTM / Processingi
Proteomic databases
PeptideAtlasi | H3BMN2 |
PRIDEi | H3BMN2 |
ProteomicsDBi | 40955 |
PTM databases
SwissPalmi | H3BMN2 |
Expressioni
Gene expression databases
Bgeei | ENSG00000140497, Expressed in esophagus mucosa and 240 other tissues |
ExpressionAtlasi | H3BMN2, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the SCAMP family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000156476 |
HOGENOMi | CLU_2471307_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR007273, SCAMP |
PANTHERi | PTHR10687, PTHR10687, 1 hit |
Pfami | View protein in Pfam PF04144, SCAMP, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
H3BMN2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLYYLWMLHS VTLFLNLLAC LAWFSGNSSK GVDFGLSILW FLIFTPCAFL
60 70 80 90
CWYRPIYKAF RSDNSFSFFV FFFVFFCQIG IYIIQLVGIP GLG
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO15127 | SCAM2_HUMAN | Secretory carrier-associated membra... | SCAMP2 | 329 | Annotation score: | ||
H3BUB6 | H3BUB6_HUMAN | Secretory carrier-associated membra... | SCAMP2 | 254 | Annotation score: | ||
H3BN93 | H3BN93_HUMAN | Secretory carrier-associated membra... | SCAMP2 | 236 | Annotation score: | ||
H3BV04 | H3BV04_HUMAN | Secretory carrier-associated membra... | SCAMP2 | 194 | Annotation score: | ||
H3BPL9 | H3BPL9_HUMAN | Secretory carrier-associated membra... | SCAMP2 | 278 | Annotation score: | ||
H3BQW2 | H3BQW2_HUMAN | Secretory carrier-associated membra... | SCAMP2 | 57 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 93 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC091230 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000565345; ENSP00000454464; ENSG00000140497 |
UCSCi | uc059lmr.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC091230 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
PTM databases
SwissPalmi | H3BMN2 |
Proteomic databases
PeptideAtlasi | H3BMN2 |
PRIDEi | H3BMN2 |
ProteomicsDBi | 40955 |
Protocols and materials databases
Antibodypediai | 14704, 276 antibodies |
Genome annotation databases
Ensembli | ENST00000565345; ENSP00000454464; ENSG00000140497 |
UCSCi | uc059lmr.1, human |
Organism-specific databases
HGNCi | HGNC:10564, SCAMP2 |
OpenTargetsi | ENSG00000140497 |
VEuPathDBi | HostDB:ENSG00000140497.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156476 |
HOGENOMi | CLU_2471307_0_0_1 |
Miscellaneous databases
ChiTaRSi | SCAMP2, human |
Gene expression databases
Bgeei | ENSG00000140497, Expressed in esophagus mucosa and 240 other tissues |
ExpressionAtlasi | H3BMN2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR007273, SCAMP |
PANTHERi | PTHR10687, PTHR10687, 1 hit |
Pfami | View protein in Pfam PF04144, SCAMP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BMN2_HUMAN | |
Accessioni | H3BMN2Primary (citable) accession number: H3BMN2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | April 7, 2021 | |
This is version 42 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |