UniProtKB - H3BMF0 (H3BMF0_HUMAN)

BLAST

>tr|H3BMF0|H3BMF0_HUMAN Mitogen-activated protein kinase kinase kinase 12 (Fragment) OS=Homo sapiens OX=9606 GN=MAP3K12 PE=4 SV=1
MACLHETRTPSPSFGGFVSTLSEAS

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History
Entry version 32 (12 Sep 2018)
Sequence version 1 (18 Apr 2012)
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Protein

Submitted name:

Mitogen-activated protein kinase kinase kinase 12

Gene

MAP3K12

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Protein predictedⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Mitogen-activated protein kinase kinase kinase 12Imported
Gene namesⁱ	Name:MAP3K12Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 12

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000139625.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:6851 MAP3K12

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000139625

OpenTargetsⁱ

ENSG00000139625

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000139625 Expressed in 212 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasⁱ	H3BMF0 baseline and differential

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG4721 Eukaryota ENOG410YKX2 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140790

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

H3BMF0-1 [UniParc]FASTA Add to basket

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        10         20 
MACLHETRTP SPSFGGFVST LSEAS

Length:25

Mass (Da):2,613

Last modified:April 18, 2012 - v1

Checksum:ⁱ34DFFB5EFD637DBE

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q12852	M3K12_HUMAN	Mitogen-activated protein kinase ki... Mitogen-activated protein kinase kinase kinase 12, EC 2.7.11.25 (Dual leucine zipper bearing kinase, DLK) (Leucine-zipper protein kinase, ZPK) (MAPK-upstream kinase, MUK) (Mixed lineage kinase)	MAP3K12 ZPK	859	Annotation score:
F8VUG4	F8VUG4_HUMAN	Mitogen-activated protein kinase ki... Mitogen-activated protein kinase kinase kinase 12	MAP3K12	393	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	25	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC023509 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC023509 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000548565; ENSP00000454355; ENSG00000139625
UCSC genome browser More...UCSCⁱ	uc058orh.1 human

Protein	Similar proteins		Species	Score	Length	Source
H3BMF0	Mitogen-activated protein kinase kinase kinase 12		Enhydra lutris kenyoni		1011	UniRef100_A0A2Y9L1I2
Mitogen-activated protein kinase kinase kinase 12 (Fragment)		MOUSE		22
Uncharacterized protein (Fragment)		COLVI		52
Mitogen-activated protein kinase kinase kinase 12, isoform CRA_c (Fragment)		NEOVI		148
Mitogen-activated protein kinase kinase kinase 12		Enhydra lutris kenyoni		996
+2

Protein	Similar proteins		Species	Score	Length	Source
H3BMF0	Mitogen-activated protein kinase kinase kinase 12		Enhydra lutris kenyoni		1011	UniRef90_A0A2Y9L1I2
Mitogen-activated protein kinase kinase kinase 12 (Fragment)		MOUSE		22
Uncharacterized protein (Fragment)		COLVI		52
Mitogen-activated protein kinase kinase kinase 12, isoform CRA_c (Fragment)		NEOVI		148
Mitogen-activated protein kinase kinase kinase 12		Enhydra lutris kenyoni		996
+3

Protein	Similar proteins		Species	Score	Length	Source
H3BMF0	Mitogen-activated protein kinase kinase kinase 12		MOUSE		888	UniRef50_Q60700
Mitogen-activated protein kinase kinase kinase 12		RAT		888
Mitogen-activated protein kinase kinase kinase 12	)	HUMAN		859
Mitogen-activated protein kinase kinase kinase 12		FUKDA		938
Mitogen-activated protein kinase kinase kinase 12		DELLE		929
+339

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC023509 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC023509 Genomic DNA No translation available.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000548565; ENSP00000454355; ENSG00000139625
UCSCⁱ	uc058orh.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000139625.12
HGNCⁱ	HGNC:6851 MAP3K12
OpenTargetsⁱ	ENSG00000139625
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG4721 Eukaryota ENOG410YKX2 LUCA
GeneTreeⁱ	ENSGT00900000140790

Miscellaneous databases

ChiTaRSⁱ	MAP3K12 human

ChiTaRSⁱ

MAP3K12 human

Gene expression databases

Bgeeⁱ	ENSG00000139625 Expressed in 212 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasⁱ	H3BMF0 baseline and differential

Family and domain databases

ProtoNetⁱ	Search...

ProtoNetⁱ

Search...

Entry informationⁱ

Entry nameⁱ	H3BMF0_HUMAN
Accessionⁱ	H3BMF0Primary (citable) accession number: H3BMF0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 18, 2012
	Last sequence update:	April 18, 2012
	Last modified:	September 12, 2018
	This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - H3BMF0 (H3BMF0_HUMAN)

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Mitogen-activated protein kinase kinase kinase 12

MAP3K12

Select a section on the left to see content.

Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Phylogenomic databases

Sequence (1+)ⁱ

Computationally mapped potential isoform sequencesⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

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Supporting data

UniProtKB - H3BMF0 (H3BMF0_HUMAN)

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Mitogen-activated protein kinase kinase kinase 12

MAP3K12

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

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Organism-specific databases

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Gene expression databases

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Phylogenomic databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Names & Taxonomyⁱ

Pathology & Biotechⁱ

Expressionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ