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Protein
Submitted name:

NEDD8 ultimate buster 1

Gene

NUB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NEDD8 ultimate buster 1Imported
Submitted name:
NEDD8 ultimate buster-1, isoform CRA_dImported
Gene namesi
Name:NUB1Imported
Synonyms:NYREN18Imported
ORF Names:hCG_19587Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000013374.15
HGNCiHGNC:17623 NUB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000013374

PTM / Processingi

Proteomic databases

EPDiH3BM14
MaxQBiH3BM14
PRIDEiH3BM14

Expressioni

Gene expression databases

BgeeiENSG00000013374 Expressed in 199 organ(s), highest expression level in testis

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini398 – 438UBAInterPro annotationAdd BLAST41
Domaini499 – 539UBAInterPro annotationAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili66 – 86Sequence analysisAdd BLAST21
Coiled coili179 – 199Sequence analysisAdd BLAST21
Coiled coili435 – 460Sequence analysisAdd BLAST26

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2561 Eukaryota
ENOG410ZK3P LUCA
GeneTreeiENSGT00390000010557

Family and domain databases

InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR015940 UBA
IPR009060 UBA-like_sf
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF00627 UBA, 2 hits
SMARTiView protein in SMART
SM00165 UBA, 2 hits
SUPFAMiSSF46934 SSF46934, 2 hits
SSF48452 SSF48452, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50030 UBA, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.iShow all

H3BM14-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTNGGRCRI RALCWSRREW RGAGMAQKKY LQAKLTQFLR EDRIQLWKPP
60 70 80 90 100
YTDENKKVGL ALKDLAKQYS DRLECCENEV EKVIEEIRCK AIERGTGNDN
110 120 130 140 150
YRTTGIATIE VFLPPRLKKD RKNLLETRLH ITGRELRSKI AETFGLQENY
160 170 180 190 200
IKIVINKKQL QLGKTLEEQG VAHNVKAMVL ELKQSEEDAR KNFQLEEEEQ
210 220 230 240 250
NEAKLKEKQI QRTKRGLEIL AKRAAETVVD PEMTPYLDIA NQTGRSIRIP
260 270 280 290 300
PSERKALMLA MGYHEKGRAF LKRKEYGIAL PCLLDADKYF CECCRELLDT
310 320 330 340 350
VDNYAVLQLD IVWCYFRLEQ LECLDDAEKK LNLAQKCFKN CYGENHQRLV
360 370 380 390 400
HIKGNCGKEK VLFLRLYLLQ GIRNYHSGND VEAYEYLNKA RQLFKELYID
410 420 430 440 450
PSKVDNLLQL GFTAQEARLG LRACDGNVDH AATHITNRRE ELAQIRKEEK
460 470 480 490 500
EKKRRRLENI RFLKGMGYST HAAQQILLSN PQMWWLNDSN PETDNRQESP
510 520 530 540 550
SQENIDRLVY MGFDALVAEA ALRVFRGNVQ LAAQTLAHNG GSLPPELPLS
560 570 580 590 600
PEDSLSPPAT SPSDSAGTSS ASTDEDMETE AVNEILEDIP EHEEDYLDST
610 620
LEDEEIIIAE YLSYVENRKS ATKKN
Length:625
Mass (Da):71,922
Last modified:April 18, 2012 - v1
Checksum:i3FCE0F9C0C881300
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y5A7NUB1_HUMAN
NEDD8 ultimate buster 1
NUB1 NYREN18
615Annotation score:
H3BM74H3BM74_HUMAN
NEDD8 ultimate buster 1
NUB1
639Annotation score:
C9JRT6C9JRT6_HUMAN
NEDD8 ultimate buster 1
NUB1
254Annotation score:
C9J7X7C9J7X7_HUMAN
NEDD8 ultimate buster 1
NUB1
154Annotation score:
F8WDB6F8WDB6_HUMAN
NEDD8 ultimate buster 1
NUB1
267Annotation score:
H7C5E1H7C5E1_HUMAN
NEDD8 ultimate buster 1
NUB1
128Annotation score:
F8WDL9F8WDL9_HUMAN
NEDD8 ultimate buster 1
NUB1
149Annotation score:
H7C5N1H7C5N1_HUMAN
NEDD8 ultimate buster 1
NUB1
202Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005486 Genomic DNA No translation available.
KF458635 Genomic DNA No translation available.
KF458638 Genomic DNA No translation available.
CH471173 Genomic DNA Translation: EAW54003.1
RefSeqiNP_057202.3, NM_016118.4
UniGeneiHs.647082

Genome annotation databases

EnsembliENST00000413040; ENSP00000398644; ENSG00000013374
GeneIDi51667
KEGGihsa:51667
UCSCiuc003wjw.6 human

Similar proteinsi

Entry informationi

Entry nameiH3BM14_HUMAN
AccessioniPrimary (citable) accession number: H3BM14
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 12, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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