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Protein
Submitted name:

Neuronal migration protein doublecortin

Gene

DCX

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Neuronal migration protein doublecortinImported
Gene namesi
Name:DCXImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000077279.16
HGNCiHGNC:2714 DCX

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000077279

PTM / Processingi

Proteomic databases

EPDiH3BLV5
PRIDEiH3BLV5

Expressioni

Gene expression databases

BgeeiENSG00000077279
ExpressionAtlasiH3BLV5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH3BLV5
SMRiH3BLV5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 139DoublecortinInterPro annotationAdd BLAST87
Domaini180 – 263DoublecortinInterPro annotationAdd BLAST84

Phylogenomic databases

eggNOGiKOG3757 Eukaryota
ENOG410ZE6Q LUCA

Family and domain databases

CDDicd01617 DCX, 2 hits
Gene3Di3.10.20.230, 2 hits
InterProiView protein in InterPro
IPR017302 Doublecortin_chordata
IPR003533 Doublecortin_dom
IPR036572 Doublecortin_dom_sf
PfamiView protein in Pfam
PF03607 DCX, 2 hits
PIRSFiPIRSF037870 Doublin, 1 hit
SMARTiView protein in SMART
SM00537 DCX, 2 hits
SUPFAMiSSF89837 SSF89837, 2 hits
PROSITEiView protein in PROSITE
PS50309 DC, 2 hits

Sequencei

Sequence statusi: Complete.

H3BLV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELDFGHFDE RDKTSRNMRG SRMNGLPSPT HSAHCSFYRT RTLQALSNEK
60 70 80 90 100
KAKKVRFYRN GDRYFKGIVY AVSSDRFRSF DALLADLTRS LSDNINLPQG
110 120 130 140 150
VRYIYTIDGS RKIGSMDELE EGESYVCSSD NFFKKVEYTK NVNPNWSVNV
160 170 180 190 200
KTSANMKAPQ SLASSNSAQA RENKDFVRPK LVTIIRSGVK PRKAVRVLLN
210 220 230 240 250
KKTAHSFEQV LTDITEAIKL ETGVVKKLYT LDGKQVTCLH DFFGDDDVFI
260 270 280 290 300
ACGPEKFRYA QDDFSLDENE CRVMKGNPSA TAGPKASPTP QKTSAKSPGP
310 320 330 340 350
MRRSKSPADS ANGTSSSQLS TPKSKQSPIS TPTSPGSLRK HKDLYLPLSL
360
DDSDSLGDSM
Length:360
Mass (Da):40,044
Last modified:October 5, 2016 - v2
Checksum:i91D0D89433AF52A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031117 Genomic DNA No translation available.
AL450490 Genomic DNA No translation available.
RefSeqiNP_835364.1, NM_178151.2
NP_835366.1, NM_178153.2
UniGeneiHs.34780

Genome annotation databases

EnsembliENST00000358070; ENSP00000350776; ENSG00000077279
GeneIDi1641
UCSCiuc065asf.1 human

Similar proteinsi

Entry informationi

Entry nameiH3BLV5_HUMAN
AccessioniPrimary (citable) accession number: H3BLV5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 47 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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