UniProtKB - H3BL23 (H3BL23_MOUSE)
Protein
Submitted name:
Ubiquitin-conjugating enzyme E2 E2
Gene
Ube2e2
Organism
Mus musculus (Mouse)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 106 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- transferase activity Source: UniProtKB-KW
Keywordsi
Molecular function | TransferaseARBA annotation |
Biological process | Ubl conjugation pathwayUniRule annotationARBA annotation |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Ubiquitin-conjugating enzyme E2 E2Imported |
Gene namesi | Name:Ube2e2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2384997, Ube2e2 |
PTM / Processingi
Proteomic databases
jPOSTi | H3BL23 |
MaxQBi | H3BL23 |
PeptideAtlasi | H3BL23 |
PTM databases
SwissPalmi | H3BL23 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000058317, Expressed in pineal body and 280 other tissues |
ExpressionAtlasi | H3BL23, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 146 | UBC coreInterPro annotationAdd BLAST | 104 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 50 | DisorderedSequence analysisAdd BLAST | 50 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 31 | PolyampholyteSequence analysisAdd BLAST | 31 |
Sequence similaritiesi
Belongs to the ubiquitin-conjugating enzyme family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000155985 |
HOGENOMi | CLU_030988_14_4_1 |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
H3BL23-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GSSDGDQRES VQQEPDREQV QPKKKEGKIS SKTAAKLSTS AKSAGPKGDN
60 70 80 90 100
IYEWRSTILG PPGSVYEGGV FFLDITFSPD YPFKPPKVTF RTRIYHCNIN
110 120 130 140
SQGVICLDIL KDNWSPALTI SKVLLSICSL LTDCNPADPL VGSIAT
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ91W82 | UB2E2_MOUSE | Ubiquitin-conjugating enzyme E2 E2 | Ube2e2 | 201 | Annotation score: | ||
D3YXD1 | D3YXD1_MOUSE | Ubiquitin-conjugating enzyme E2 E2 | Ube2e2 | 181 | Annotation score: | ||
H3BL69 | H3BL69_MOUSE | Ubiquitin-conjugating enzyme E2 E2 | Ube2e2 | 167 | Annotation score: | ||
D3YW10 | D3YW10_MOUSE | Ubiquitin-conjugating enzyme E2 E2 | Ube2e2 | 108 | Annotation score: | ||
H3BJB5 | H3BJB5_MOUSE | Ubiquitin-conjugating enzyme E2 E2 | Ube2e2 | 92 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 146 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC118006 Genomic DNA No translation available. AC121296 Genomic DNA No translation available. AC132459 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000176843; ENSMUSP00000135622; ENSMUSG00000058317 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC118006 Genomic DNA No translation available. AC121296 Genomic DNA No translation available. AC132459 Genomic DNA No translation available. |
3D structure databases
SMRi | H3BL23 |
ModBasei | Search... |
PTM databases
SwissPalmi | H3BL23 |
Proteomic databases
jPOSTi | H3BL23 |
MaxQBi | H3BL23 |
PeptideAtlasi | H3BL23 |
Protocols and materials databases
Antibodypediai | 11339, 168 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000176843; ENSMUSP00000135622; ENSMUSG00000058317 |
Organism-specific databases
MGIi | MGI:2384997, Ube2e2 |
Phylogenomic databases
GeneTreei | ENSGT00940000155985 |
HOGENOMi | CLU_030988_14_4_1 |
Miscellaneous databases
ChiTaRSi | Ube2e2, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000058317, Expressed in pineal body and 280 other tissues |
ExpressionAtlasi | H3BL23, baseline and differential |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3BL23_MOUSE | |
Accessioni | H3BL23Primary (citable) accession number: H3BL23 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | October 7, 2020 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |