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Entry version 31 (05 Jun 2019)
Sequence version 1 (18 Apr 2012)
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Protein
Submitted name:

RRN3 homolog, RNA polymerase I transcription factor

Gene

RRN3

Organism
Latimeria chalumnae (Coelacanth)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RRN3 homolog, RNA polymerase I transcription factorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RRN3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLatimeria chalumnae (Coelacanth)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7897 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiCoelacanthiformesCoelacanthidaeLatimeria
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008672 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7897.ENSLACP00000015467

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG2434 Eukaryota
ENOG410XRJJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001488

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H3B0P6

Identification of Orthologs from Complete Genome Data

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OMAi
PLKVCSP

TreeFam database of animal gene trees

More...
TreeFami
TF312979

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR007991 RNA_pol_I_trans_ini_fac_RRN3

The PANTHER Classification System

More...
PANTHERi
PTHR12790 PTHR12790, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF05327 RRN3, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H3B0P6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRGDDMFLS SPPRKAVRFG GSVTDVLMKY KEGDSTDYEL LKHQLFDPDI
60 70 80 90 100
KDDQIINWLQ EFRNAVNYLT KDFEQLVTIV LKLPWLDRSQ DVREEYLAFL
110 120 130 140 150
GNLVSAQTVY LRACLSMVIS KFVPQRVIIR EGGVDISDSE DEDESLPRRF
160 170 180 190 200
ETCHRALQII ARYVPSTPRF LHPILVEKFP FYNKSANALT GYLEMRLFWI
210 220 230 240 250
QKFFSWLNEY DLTGFYCKCV LLLQVSAPRS DIEDAEEAAE QHEATGPVEE
260 270 280 290 300
GLFDMDEDEE DKNTVSGAAG NDSMAHPVAE RLDIIMSVVF AYIKDICYTN
310 320 330 340 350
GAFDLNKTKD LYRDLIAVFD KLILPTHASC HVQYLIFYIC SFKLGLAEAF
360 370 380 390 400
LEHLWKKLQN PNNPAVIRQA AAGYMGSFLA RAKFIPVVTL KACLDLLIPW
410 420 430 440 450
LHQYIDHQGA GTKAFCDVAL HGPFYSTCQA VFYTLVFRHR QLLDGNLKKG
460 470 480 490 500
LAYLQNLNFE RIVMCQLNPL KVCLPSVVNL FAAITRKYQL VFCYTIIERN
510 520 530 540 550
NRQQLPVVRS SIGGDLVQTC TNPLDSFFPF DPYCLKRSKR VIDPLYQVWE
560 570 580 590 600
DLSIQDLPDS QQPIKEAIDE DEEDDFLKGE TPQNDGVIGM TPGSYDSSIW
610
SPSSVGSPPL ILYLKICPL
Length:619
Mass (Da):70,641
Last modified:April 18, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i751748D53180587B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AFYH01123054 Genomic DNA No translation available.
AFYH01123055 Genomic DNA No translation available.
AFYH01123056 Genomic DNA No translation available.
AFYH01123057 Genomic DNA No translation available.
AFYH01123058 Genomic DNA No translation available.
AFYH01123059 Genomic DNA No translation available.
AFYH01123060 Genomic DNA No translation available.
AFYH01123061 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSLACT00000015574; ENSLACP00000015467; ENSLACG00000013619

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AFYH01123054 Genomic DNA No translation available.
AFYH01123055 Genomic DNA No translation available.
AFYH01123056 Genomic DNA No translation available.
AFYH01123057 Genomic DNA No translation available.
AFYH01123058 Genomic DNA No translation available.
AFYH01123059 Genomic DNA No translation available.
AFYH01123060 Genomic DNA No translation available.
AFYH01123061 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7897.ENSLACP00000015467

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSLACT00000015574; ENSLACP00000015467; ENSLACG00000013619

Phylogenomic databases

eggNOGiKOG2434 Eukaryota
ENOG410XRJJ LUCA
GeneTreeiENSGT00390000001488
InParanoidiH3B0P6
OMAiPLKVCSP
TreeFamiTF312979

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR007991 RNA_pol_I_trans_ini_fac_RRN3
PANTHERiPTHR12790 PTHR12790, 1 hit
PfamiView protein in Pfam
PF05327 RRN3, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH3B0P6_LATCH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H3B0P6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: June 5, 2019
This is version 31 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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