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Protein

Caveolin

Gene

CAV1

Organism
Latimeria chalumnae (West Indian ocean coelacanth)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
CaveolinUniRule annotation
Gene namesi
Name:CAV1Imported
OrganismiLatimeria chalumnae (West Indian ocean coelacanth)Imported
Taxonomic identifieri7897 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiCoelacanthiformesCoelacanthidaeLatimeria
Proteomesi
  • UP000008672 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei72 – 99HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Golgi apparatusUniRule annotationSAAS annotation, Membrane

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7897.ENSLACP00000014173

Family & Domainsi

Sequence similaritiesi

Belongs to the caveolin family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IV7A Eukaryota
ENOG4111HJR LUCA
GeneTreeiENSGT00390000014924
InParanoidiH3AX02
OMAiIYVHTFC
OrthoDBiEOG091G0M1R
TreeFamiTF315736

Family and domain databases

InterProiView protein in InterPro
IPR015504 CAV-1
IPR001612 Caveolin
IPR018361 Caveolin_CS
PANTHERiPTHR10844 PTHR10844, 1 hit
PTHR10844:SF18 PTHR10844:SF18, 1 hit
PfamiView protein in Pfam
PF01146 Caveolin, 1 hit
PROSITEiView protein in PROSITE
PS01210 CAVEOLIN, 1 hit

Sequencei

Sequence statusi: Complete.

H3AX02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADDSYNEKV MRDVHTKEID LVNRDPKHLN DDVVKVDFED VIAEPEGTYS
60 70 80 90 100
FDGIWKASFT TFTVSKYWCY RLLSAIFGIP MALIWGIYFA ILSFLHIWAV
110 120 130 140
VPCIKSYLIE IQCISRVYSI FIHTFCDPLF EAMGKMFSSI RATLHKEV
Length:148
Mass (Da):17,190
Last modified:April 18, 2012 - v1
Checksum:i6C438073F4179551
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AFYH01075721 Genomic DNA No translation available.
AFYH01075722 Genomic DNA No translation available.
AFYH01075723 Genomic DNA No translation available.
AFYH01075724 Genomic DNA No translation available.
RefSeqiXP_005996740.1, XM_005996678.2

Genome annotation databases

EnsembliENSLACT00000014272; ENSLACP00000014173; ENSLACG00000012477
GeneIDi102365573

Similar proteinsi

Entry informationi

Entry nameiH3AX02_LATCH
AccessioniPrimary (citable) accession number: H3AX02
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: March 28, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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