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Protein

Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

Gene

C1GALT1

Organism
Latimeria chalumnae (West Indian ocean coelacanth)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.UniRule annotation

Catalytic activityi

UDP-alpha-D-galactose + N-acetyl-alpha-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1UniRule annotation (EC:2.4.1.122UniRule annotation)
Gene namesi
Name:C1GALT1Imported
OrganismiLatimeria chalumnae (West Indian ocean coelacanth)Imported
Taxonomic identifieri7897 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiCoelacanthiformesCoelacanthidaeLatimeria
Proteomesi
  • UP000008672 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 28HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi7897.ENSLACP00000009133

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.UniRule annotation

Keywords - Domaini

Signal-anchorUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2246 Eukaryota
ENOG410YRJG LUCA
GeneTreeiENSGT00530000063264
InParanoidiH3AHL2
KOiK00731
OMAiERWHADK
OrthoDBiEOG091G0BLV
TreeFamiTF317293

Family and domain databases

InterProiView protein in InterPro
IPR026842 C1GALT1
IPR003378 Fringe-like
PANTHERiPTHR23033:SF13 PTHR23033:SF13, 1 hit
PfamiView protein in Pfam
PF02434 Fringe, 1 hit

Sequencei

Sequence statusi: Complete.

H3AHL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSRSAVNS FTFFCGLASG FCFCYLVFNT VFVKELRPKP HLVYNDPHGG
60 70 80 90 100
HHAEDSDDLV LLGQMNFNAD AWQHKDEDRS VAEDLSKKVR ILCWVMTGPQ
110 120 130 140 150
NLQTKAKHVK ATWAQHCNKV LFMSSTDDKD FPAIGLDTKE GRDQLYWKTI
160 170 180 190 200
KAFQYVQEHH LNDADWFMKA DDDTFVVVDN LRWILSKYSP DKPIYFGRRF
210 220 230 240 250
KPYVKQGYMS GGAGYILSKE ALNRFVEAFR LQKCSHTSSV EDLALGKCME
260 270 280 290 300
NINVEAGDSR DTIGRETFHP FVPEHLLIRN YLPQTFWYWK YNFYPAVEGP
310 320 330 340 350
GCCSDFAVSF HYVDSTTMYV LEYLVHHLRP YGYRYRYKPD QTVAKGDGQH
360
DKNDENNEVK N
Length:361
Mass (Da):41,853
Last modified:April 18, 2012 - v1
Checksum:i1F673CD03FE7610E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AFYH01102755 Genomic DNA No translation available.
AFYH01102756 Genomic DNA No translation available.
RefSeqiXP_005999515.1, XM_005999453.2

Genome annotation databases

EnsembliENSLACT00000009202; ENSLACP00000009133; ENSLACG00000008062
GeneIDi102345499
KEGGilcm:102345499

Similar proteinsi

Entry informationi

Entry nameiH3AHL2_LATCH
AccessioniPrimary (citable) accession number: H3AHL2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2012
Last sequence update: April 18, 2012
Last modified: March 28, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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