UniProtKB - H3AE42 (H3AE42_LATCH)
Protein
NR LBD domain-containing protein
Gene
NR0B1
Organism
Latimeria chalumnae (Coelacanth)
Status
Functioni
GO - Biological processi
- negative regulation of male gonad development Source: Ensembl
- water homeostasis Source: Ensembl
Keywordsi
Molecular function | ReceptorARBA annotation, RepressorARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: NR LBD domain-containing proteinInterPro annotation |
Gene namesi | Name:NR0B1Imported |
Organismi | Latimeria chalumnae (Coelacanth)Imported |
Taxonomic identifieri | 7897 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Coelacanthiformes › Coelacanthidae › Latimeria |
Proteomesi |
|
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 14 – 260 | NR LBDInterPro annotationAdd BLAST | 247 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 191 – 211 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG3575, Eukaryota |
GeneTreei | ENSGT00390000015719 |
HOGENOMi | CLU_093194_0_0_1 |
InParanoidi | H3AE42 |
OMAi | RCLHYIQ |
OrthoDBi | 955476at2759 |
TreeFami | TF332386 |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit |
InterProi | View protein in InterPro IPR035500, NHR-like_dom_sf IPR033544, NR0B1/2 IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001723, Nuclear_hrmn_rcpt |
PANTHERi | PTHR24081, PTHR24081, 2 hits |
Pfami | View protein in Pfam PF00104, Hormone_recep, 1 hit |
PRINTSi | PR00398, STRDHORMONER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit |
i Sequence
Sequence statusi: Complete.
H3AE42-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAFLDKCHCA GEKRQSSILY SILKNDNQSE LQKRQQQSAA RRQNCSCGSE
60 70 80 90 100
RRVALRCPQF ACKAASAVLV KTLKFVKNVP SFQELPLADQ LLVLRGCWAP
110 120 130 140 150
LLVLGLAQDR VDFEVTEAPE PSMLQRILTS SPEKNDEQQH QAAPSAADIH
160 170 180 190 200
CIKTFLEKCW SLDICTKEYA YLKGCVLFNP DLPGLQNAHY IQGLQKEAQQ
210 220 230 240 250
ALNEYIKMIH RGDPTRFTKL ITGLSVLRSI SASVVSELFF RPIIGTVSMD
260
DMLLEMLYAK L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AFYH01192072 Genomic DNA No translation available. |
RefSeqi | XP_006008193.1, XM_006008131.2 |
Genome annotation databases
Ensembli | ENSLACT00000007979; ENSLACP00000007913; ENSLACG00000007003 |
GeneIDi | 102361034 |
KEGGi | lcm:102361034 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AFYH01192072 Genomic DNA No translation available. |
RefSeqi | XP_006008193.1, XM_006008131.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7897.ENSLACP00000007913 |
Genome annotation databases
Ensembli | ENSLACT00000007979; ENSLACP00000007913; ENSLACG00000007003 |
GeneIDi | 102361034 |
KEGGi | lcm:102361034 |
Organism-specific databases
CTDi | 190 |
Phylogenomic databases
eggNOGi | KOG3575, Eukaryota |
GeneTreei | ENSGT00390000015719 |
HOGENOMi | CLU_093194_0_0_1 |
InParanoidi | H3AE42 |
OMAi | RCLHYIQ |
OrthoDBi | 955476at2759 |
TreeFami | TF332386 |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit |
InterProi | View protein in InterPro IPR035500, NHR-like_dom_sf IPR033544, NR0B1/2 IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001723, Nuclear_hrmn_rcpt |
PANTHERi | PTHR24081, PTHR24081, 2 hits |
Pfami | View protein in Pfam PF00104, Hormone_recep, 1 hit |
PRINTSi | PR00398, STRDHORMONER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H3AE42_LATCH | |
Accessioni | H3AE42Primary (citable) accession number: H3AE42 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 18, 2012 |
Last sequence update: | April 18, 2012 | |
Last modified: | December 2, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |